Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 3149553 . A C CCDS31729.1:NM_003213.3:c.1214cAg>cCg_NP_003204.2:p.405Q>P Homo sapiens TEA domain transcription factor 4 (TEAD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ge3 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 GLN A:190 A:405 123.0 0.683 65.9 13.0 123.0 0.683 0.0 HOH
 2.814
 O
 O
6gec 1 Q15561 100.0 3e-166 X-RAY
 2018-09-19 GLN A:190 A:405 125.0 0.694 66.6 11.4 125.0 0.694 0.0 HOH
 2.618
 OE1
 O
6ge5 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLN A:190 A:405 123.0 0.683 66.2 13.7 123.0 0.683 0.0 HOH
 2.738
 O
 O
6geg 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLN A:190 A:405 126.0 0.7 66.6 13.8 126.0 0.7 0.0 HOH
 2.686
 NE2
 O
6gek 1 Q15561 99.54 1e-165 X-RAY
 2018-09-19 GLN A:190 A:405 105.0 0.583 61.5 20.3 105.0 0.583 0.0 HOH
 3.931
 O
 O
GLN C:190 B:405 106.0 0.589 74.6 5.2 NA NA NA
6hik 1 Q15561 99.54 2e-165 X-RAY
 2019-04-03 GLN A:190 A:405 126.0 0.7 66.5 11.9 126.0 0.7 0.0 HOH
 2.637
 O
 O
6ge4 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 GLN A:190 A:405 120.0 0.667 65.7 14.9 120.0 0.667 0.0 HOH
 2.651
 OE1
 O
6gee 1 Q15561 99.54 2e-165 X-RAY
 2018-09-19 GLN A:190 A:405 125.0 0.694 67.9 15.0 125.0 0.694 0.0 HOH
 2.565
 OE1
 O
5oaq 1 Q15561 100.0 5e-165 X-RAY
 2017-10-11 GLN A:191 A:405 126.0 0.7 64.8 11.4 126.0 0.7 0.0 HOH
 2.750
 NE2
 O
6q2x 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 GLN A:191 A:405 123.0 0.683 66.1 12.1 123.0 0.683 0.0 HOH
 2.650
 NE2
 O
6q36 1 Q15561 100.0 5e-165 X-RAY
 2019-07-03 GLN A:191 A:405 114.0 0.633 64.6 14.2 114.0 0.633 0.0 HOH
 3.384
 NE2
 O
GLN B:191 B:405 167.0 0.928 59.2 15.8 167.0 0.928 0.0 HOH
 3.833
 O
 O
6ge6 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 GLN A:190 A:405 125.0 0.694 65.1 15.4 125.0 0.694 0.0 HOH
 2.730
 O
 O
6gei 1 Q15561 99.09 1e-164 X-RAY
 2018-09-19 GLN A:190 A:405 128.0 0.711 65.4 13.4 128.0 0.711 0.0 HOH
 2.639
 O
 O
6sen 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 GLN A:191 A:405 129.0 0.717 64.6 13.0 129.0 0.717 0.0 HOH
 3.039
 NE2
 O
GLN B:191 B:405 134.0 0.744 69.5 12.7 NA NA NA
6seo 1 Q15561 99.54 5e-164 X-RAY
 2019-11-20 GLN A:191 A:405 142.0 0.789 60.4 16.3 142.0 0.789 0.0 HOH
 5.878
 O
 O
4ln0 1 Q62296 96.35 3e-161 X-RAY
 2014-02-26 GLN A:193 A:398 103.0 0.572 60.5 9.5 103.0 0.572 0.0
GLN B:193 B:398 71.0 NA 63.7 7.4 71.0 NA NA
6l9f 1 Q62296 96.35 3e-161 X-RAY
 2019-12-11 GLN A:193 A:398 118.0 0.656 61.0 14.4 118.0 0.656 0.0 HOH
 2.746
 NE2
 O
GLN C:193 B:398 114.0 0.633 63.5 17.6 NA NA NA
6sba 1 Q62296 96.35 9e-161 X-RAY
 2020-09-30 GLN A:192 A:398 104.0 0.578 70.1 13.4 104.0 0.578 0.0 HOH
 2.699
 O
 O
3jua 1 Q62296 96.33 2e-160 X-RAY
 2010-02-23 GLN A:191 A:398 138.0 0.767 -67.2 32.8 138.0 0.767 0.0 HOH
 3.248
 OE1
 O
GLN C:191 C:398 156.0 0.867 -104.2 36.1 NA NA NA
GLN E:191 E:398 131.0 0.728 -118.6 40.0 NA NA NA
GLN G:191 G:398 128.0 0.711 64.7 12.6 NA NA NA
5xjd 1 Q62296 96.33 2e-160 X-RAY
 2018-01-24 GLN A:191 A:398 116.0 0.644 62.6 14.8 116.0 0.644 0.0 HOH
 2.944
 NE2
 O
GLN B:191 B:398 120.0 0.667 63.4 14.8 120.0 0.667 0.0 HOH
 2.831
 NE2
 O
5gn0 1 Q62296 96.33 4e-160 X-RAY
 2017-05-31 GLN A:196 A:398 121.0 0.672 74.1 8.7 121.0 0.672 0.0 HOH
 2.970
 OE1
 O
GLN B:196 B:398 112.0 0.622 72.1 15.6 NA NA NA
GLN C:196 C:398 131.0 0.728 76.5 10.1 NA NA NA
GLN D:196 D:398 137.0 0.761 80.5 6.8 NA NA NA
5z2q 3 Q62296 96.31 1e-159 X-RAY
 2018-01-31 GLN C:198 A:398 156.0 0.867 -67.1 47.2 NA NA NA
5z2q 4 Q62296 96.31 2e-159 X-RAY
 2018-01-31 GLN D:200 B:398 128.0 0.711 48.6 53.2 128.0 0.711 0.0
7cmm 1 P28347 81.45 8e-139 X-RAY
 2021-02-03 GLN A:201 A:397 146.0 0.811 T 61.7 37.2 146.0 0.811 0.0
GLN B:201 B:397 137.0 0.761 T 54.4 36.9 NA NA NA
GLN C:201 C:397 126.0 0.7 T 61.7 37.3 NA NA NA
GLN D:201 D:397 136.0 0.756 T 55.9 38.7 NA NA NA
4re1 1 P28347 81.28 2e-137 X-RAY
 2014-11-19 GLN A:191 A:382 114.0 0.633 59.1 12.3 114.0 0.633 0.0 HOH
 4.244
 O
 O
GLN B:191 B:382 118.0 0.656 59.5 12.1 NA NA NA
6hil 1 P28347 81.65 4e-137 X-RAY
 2019-04-03 GLN A:190 A:382 123.0 0.683 T 81.8 21.3 123.0 0.683 0.0 HOH
 6.990
 N
 O
GLN C:190 D:382 119.0 0.661 76.8 11.2 NA NA NA
GLN E:190 B:382 136.0 0.756 88.3 6.3 NA NA NA
GLN G:190 C:382 121.0 0.672 72.5 3.7 NA NA NA
3kys 1 P28347 81.65 4e-137 X-RAY
 2010-02-23 GLN A:190 A:382 107.0 0.594 58.8 17.7 107.0 0.594 0.0 HOH
 5.753
 O
 O
GLN C:190 C:382 125.0 0.694 57.2 18.0 NA NA NA
6im5 1 P28347 81.36 2e-136 X-RAY
 2019-02-06 GLN A:204 A:397 121.0 0.672 66.3 15.9 121.0 0.672 0.0 HOH
 2.622
 O
 O
GLN B:204 B:397 143.0 0.794 59.4 19.9 NA NA NA
7li5 1 E9PKB7 81.94 6e-136 X-RAY
 2022-02-02 GLN A:193 A:397 112.0 0.622 67.8 12.1 112.0 0.622 0.0 HOH
 2.421
 O
 O
GLN B:193 B:397 137.0 0.761 73.5 5.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15561-f1 1 Q15561 100.0 0.0 GLN A:405 A:405 118.0 0.656 59.7 15.9