Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 50452817 | . | G | A | CCDS8796.1:NM_020039.3:c.268Gtc>Atc_NP_064423.2:p.90V>I | Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7rnn | 2 | P78348 | 91.46 | 0.0 |
EM |
2021-08-11 | VAL | B:90 | D:90 | 0.0 | 0.0 | E | -120.4 | 102.1 | 0.0 | 0.0 | 0.0 | ||||||
| 6ave | 1 | Q1XA76 | 82.06 | 0.0 |
EM |
2018-03-21 | VAL | A:91 | A:91 | 1.0 | 0.006 | E | -101.7 | 136.7 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | B:91 | B:91 | 0.0 | 0.0 | E | -101.6 | 136.7 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | C:91 | C:91 | 0.0 | 0.0 | E | -101.7 | 136.6 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6vtk | 1 | Q1XA76 | 82.06 | 0.0 |
EM |
2020-03-11 | VAL | A:91 | A:91 | 0.0 | 0.0 | E | -118.5 | 111.2 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:91 | C:91 | 0.0 | 0.0 | E | -118.5 | 111.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | C:91 | B:91 | 0.0 | 0.0 | E | -118.5 | 111.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6vtl | 1 | Q1XA76 | 82.06 | 0.0 |
EM |
2020-03-11 | VAL | A:91 | A:91 | 1.0 | 0.006 | E | -72.1 | 108.3 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | B:91 | C:91 | 1.0 | 0.006 | E | -72.0 | 108.2 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | C:91 | B:91 | 1.0 | 0.006 | E | -72.1 | 108.3 | 1.0 | 0.006 | 0.0 | |||||||||||||
| 7cfs | 1 | P78348 | 91.05 | 0.0 |
EM |
2020-10-21 | VAL | A:99 | A:90 | 0.0 | 0.0 | E | -71.1 | 136.3 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:99 | B:90 | 1.0 | 0.006 | E | -71.1 | 136.2 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | C:99 | C:90 | 0.0 | 0.0 | E | -71.1 | 136.2 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 7cft | 1 | P78348 | 91.05 | 0.0 |
EM |
2020-10-21 | VAL | A:99 | A:90 | 0.0 | 0.0 | E | -89.5 | 124.3 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:99 | B:90 | 0.0 | 0.0 | E | -89.4 | 124.2 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | C:99 | C:90 | 0.0 | 0.0 | E | -89.5 | 124.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6l6i | 1 | P78348 | 90.0 | 0.0 |
X-RAY |
2020-11-04 | VAL | A:80 | A:90 | 0.0 | 0.0 | E | -128.2 | 100.7 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:80 | B:90 | 0.0 | 0.0 | E | -128.5 | 100.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | C:80 | C:90 | 0.0 | 0.0 | E | -128.9 | 100.7 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6l6n | 1 | P78348 | 90.0 | 0.0 |
X-RAY |
2021-01-13 | VAL | A:80 | A:90 | 0.0 | 0.0 | E | -127.2 | 101.4 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:80 | B:90 | 0.0 | 0.0 | E | -126.7 | 102.1 | 0.0 | 0.0 | 0.0 |
HOH |
9.495 |
N |
O |
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| VAL | C:80 | C:90 | 0.0 | 0.0 | E | -128.2 | 101.5 | 0.0 | 0.0 | 0.0 |
HOH |
9.436 |
N |
O |
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| 4nyk | 1 | Q1XA76 | 81.29 | 0.0 |
X-RAY |
2014-02-12 | VAL | A:95 | A:91 | 2.0 | 0.013 | E | -126.4 | 112.0 | 2.0 | 0.013 | 0.0 |
HOH |
8.026 |
CA |
O |
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| 3ij4 | 1 | Q1XA76 | 81.29 | 0.0 |
X-RAY |
2009-11-10 | VAL | A:90 | A:91 | 1.0 | 0.006 | E | -121.3 | 109.4 | 1.0 | 0.006 | 0.0 |
HOH |
7.929 |
CA |
O |
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| 4fz0 | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2012-08-01 | VAL | A:78 | A:91 | 2.0 | 0.013 | E | -121.9 | 112.0 | 2.0 | 0.013 | 0.0 |
HOH |
7.000 |
N |
O |
||
| VAL | B:78 | B:91 | 2.0 | 0.013 | E | -121.6 | 113.0 | 2.0 | 0.013 | 0.0 |
HOH |
6.691 |
O |
O |
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| VAL | C:78 | C:91 | 2.0 | 0.013 | E | -119.0 | 113.3 | 2.0 | 0.013 | 0.0 |
HOH |
6.671 |
O |
O |
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| 4fz1 | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2012-08-01 | VAL | A:78 | A:91 | 5.0 | 0.032 | E | -126.8 | 111.6 | 5.0 | 0.032 | 0.0 | ||||||
| 4ntw | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2014-02-19 | VAL | A:78 | A:91 | 4.0 | 0.026 | E | -131.2 | 111.6 | 4.0 | 0.026 | 0.0 |
HOH |
6.879 |
N |
O |
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| 4ntx | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2014-02-19 | VAL | A:78 | A:91 | 2.0 | 0.013 | E | -131.0 | 112.5 | 2.0 | 0.013 | 0.0 |
HOH |
6.949 |
O |
O |
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| 4nty | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2014-02-19 | VAL | A:78 | A:91 | 2.0 | 0.013 | E | -133.2 | 102.4 | 2.0 | 0.013 | 0.0 |
HOH |
7.156 |
C |
O |
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| 6cmc | 1 | Q1XA76 | 81.89 | 0.0 |
X-RAY |
2018-08-08 | VAL | A:78 | A:91 | 4.0 | 0.026 | E | -126.1 | 112.0 | 4.0 | 0.026 | 0.0 | ||||||
| 5wku | 1 | Q1XA76 | 81.52 | 0.0 |
X-RAY |
2018-03-14 | VAL | A:67 | A:91 | 0.0 | 0.0 | E | -120.1 | 114.2 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:67 | C:91 | 1.0 | 0.006 | E | -121.0 | 113.3 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | C:67 | B:91 | 0.0 | 0.0 | E | -122.3 | 114.2 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 5wkv | 1 | Q1XA76 | 81.52 | 0.0 |
X-RAY |
2018-03-14 | VAL | A:67 | A:91 | 1.0 | 0.006 | E | -120.3 | 113.8 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | B:67 | C:91 | 1.0 | 0.006 | E | -120.8 | 113.2 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | C:67 | B:91 | 1.0 | 0.006 | E | -122.1 | 113.9 | 1.0 | 0.006 | 0.0 | |||||||||||||
| 5wkx | 1 | Q1XA76 | 81.52 | 0.0 |
X-RAY |
2018-08-08 | VAL | A:67 | A:91 | 0.0 | 0.0 | E | -120.1 | 114.3 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:67 | C:91 | 1.0 | 0.006 | E | -121.0 | 113.3 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | C:67 | B:91 | 1.0 | 0.006 | E | -122.3 | 114.2 | 1.0 | 0.006 | 0.0 | |||||||||||||
| 5wky | 1 | Q1XA76 | 81.52 | 0.0 |
X-RAY |
2018-08-08 | VAL | A:67 | A:91 | 0.0 | 0.0 | E | -120.1 | 114.3 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:67 | C:91 | 1.0 | 0.006 | E | -121.0 | 113.4 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | C:67 | B:91 | 0.0 | 0.0 | E | -122.3 | 114.2 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 2qts | 1 | Q1XA76 | 81.48 | 0.0 |
X-RAY |
2007-09-25 | VAL | A:66 | A:91 | 5.0 | 0.032 | E | -126.9 | 113.8 | 5.0 | 0.032 | 0.0 |
HOH |
6.830 |
N |
O |
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| VAL | B:66 | B:91 | 4.0 | 0.026 | E | -129.8 | 112.9 | 4.0 | 0.026 | 0.0 |
HOH |
6.925 |
O |
O |
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| VAL | C:66 | C:91 | 4.0 | 0.026 | E | -128.6 | 114.1 | 4.0 | 0.026 | 0.0 |
HOH |
6.959 |
O |
O |
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| VAL | D:66 | D:91 | 7.0 | 0.045 | E | -131.5 | 113.1 | NA | NA | NA | |||||||||||||
| VAL | E:66 | E:91 | 4.0 | 0.026 | E | -127.5 | 112.5 | NA | NA | NA | |||||||||||||
| VAL | F:66 | F:91 | 3.0 | 0.019 | E | -128.5 | 114.3 | NA | NA | NA | |||||||||||||
| 6x9h | 1 | Q1XA76 | 81.48 | 0.0 |
X-RAY |
2020-12-30 | VAL | A:66 | A:91 | 1.0 | 0.006 | E | -129.3 | 117.3 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | B:66 | B:91 | 1.0 | 0.006 | E | -130.0 | 114.2 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | C:66 | C:91 | 1.0 | 0.006 | E | -127.8 | 115.7 | 1.0 | 0.006 | 0.0 | |||||||||||||
| 3s3w | 1 | Q1XA76 | 81.48 | 0.0 |
X-RAY |
2012-05-23 | VAL | A:87 | A:91 | 2.0 | 0.013 | E | -122.2 | 111.8 | 2.0 | 0.013 | 0.0 |
HOH |
6.667 |
O |
O |
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| VAL | B:87 | B:91 | 2.0 | 0.013 | E | -122.4 | 111.9 | 2.0 | 0.013 | 0.0 |
HOH |
6.839 |
O |
O |
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| VAL | C:87 | C:91 | 2.0 | 0.013 | E | -122.6 | 112.1 | 2.0 | 0.013 | 0.0 |
HOH |
7.211 |
O |
O |
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| 3s3x | 1 | Q1XA76 | 81.48 | 0.0 |
X-RAY |
2012-05-23 | VAL | A:87 | A:91 | 0.0 | 0.0 | E | -120.7 | 96.3 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:87 | B:91 | 0.0 | 0.0 | E | -119.7 | 96.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | C:87 | C:91 | 1.0 | 0.006 | E | -119.8 | 96.6 | 1.0 | 0.006 | 0.0 |
HOH |
8.768 |
N |
O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p78348-f1 | 1 | P78348 | 91.99 | 0.0 | VAL | A:90 | A:90 | 0.0 | 0.0 | E | -116.6 | 106.1 | |