Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50453643 . G A CCDS8796.1:NM_020039.3:c.464cGt>cAt_NP_064423.2:p.155R>H Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 ARG B:155 D:155 82.0 0.364 H -59.1 -43.5 82.0 0.364 0.0
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 LEU A:156 A:156 57.0 0.335 H -76.5 -30.6 57.0 0.335 0.0
LEU B:156 B:156 58.0 0.341 H -76.6 -30.7 58.0 0.341 0.0
LEU C:156 C:156 58.0 0.341 H -76.6 -30.7 58.0 0.341 0.0
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 LEU A:156 A:156 46.0 0.271 H -68.9 -32.6 46.0 0.271 0.0
LEU B:156 C:156 47.0 0.276 H -68.9 -32.7 47.0 0.276 0.0
LEU C:156 B:156 46.0 0.271 H -68.9 -32.7 46.0 0.271 0.0
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 LEU A:156 A:156 46.0 0.271 H -71.6 -36.6 46.0 0.271 0.0
LEU B:156 C:156 47.0 0.276 H -71.6 -36.6 47.0 0.276 0.0
LEU C:156 B:156 47.0 0.276 H -71.5 -36.7 47.0 0.276 0.0
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 ARG A:164 A:155 103.0 0.458 H -70.3 -33.8 103.0 0.458 0.0
ARG B:164 B:155 101.0 0.449 H -70.3 -33.8 101.0 0.449 0.0
ARG C:164 C:155 101.0 0.449 H -70.3 -33.9 101.0 0.449 0.0
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 ARG A:164 A:155 83.0 0.369 H -64.3 -33.6 83.0 0.369 0.0
ARG B:164 B:155 85.0 0.378 H -64.2 -33.7 85.0 0.378 0.0
ARG C:164 C:155 84.0 0.373 H -64.3 -33.6 84.0 0.373 0.0
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 ARG A:145 A:155 80.0 0.356 H -54.7 -49.3 80.0 0.356 0.0
ARG B:145 B:155 80.0 0.356 H -54.0 -50.5 80.0 0.356 0.0
ARG C:145 C:155 81.0 0.36 H -54.1 -50.9 81.0 0.36 0.0
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 ARG A:145 A:155 80.0 0.356 H -59.2 -47.8 80.0 0.356 0.0
ARG B:145 B:155 78.0 0.347 H -60.6 -46.5 78.0 0.347 0.0
ARG C:145 C:155 82.0 0.364 H -59.9 -46.3 82.0 0.364 0.0 HOH
 7.125
 NH2
 O
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 LEU A:160 A:156 44.0 0.259 H -62.9 -44.2 44.0 0.259 0.0 HOH
 3.538
 CG
 O
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 LEU A:155 A:156 45.0 0.265 H -61.5 -43.4 45.0 0.265 0.0 HOH
 3.344
 CD2
 O
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 LEU A:143 A:156 42.0 0.247 H -55.3 -49.4 42.0 0.247 0.0 HOH
 9.851
 O
 O
LEU B:143 B:156 44.0 0.259 H -56.8 -49.7 44.0 0.259 0.0 HOH
 6.033
 CB
 O
LEU C:143 C:156 50.0 0.294 H -54.6 -49.8 50.0 0.294 0.0 GOL
HOH
 5.287
3.761
 N
CD2
 O2
O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 LEU A:143 A:156 41.0 0.241 H -66.8 -50.7 41.0 0.241 0.0
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 LEU A:143 A:156 40.0 0.235 H -67.2 -42.0 40.0 0.235 0.0 HOH
 3.745
 CD2
 O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 LEU A:143 A:156 40.0 0.235 H -66.4 -45.3 40.0 0.235 0.0 HOH
 5.067
 N
 O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 LEU A:143 A:156 39.0 0.229 H -67.3 -38.3 39.0 0.229 0.0 CS
HOH
 3.917
4.005
 CD2
CG
 CS
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 LEU A:143 A:156 44.0 0.259 H -62.5 -43.7 44.0 0.259 0.0
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 LEU A:132 A:156 33.0 0.194 H -73.7 -35.6 33.0 0.194 0.0
LEU B:132 C:156 23.0 0.135 H -74.1 -32.3 23.0 0.135 0.0
LEU C:132 B:156 27.0 0.159 H -72.1 -35.8 27.0 0.159 0.0
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 LEU A:132 A:156 32.0 0.188 H -73.1 -35.2 32.0 0.188 0.0
LEU B:132 C:156 23.0 0.135 H -74.0 -32.1 23.0 0.135 0.0
LEU C:132 B:156 24.0 0.141 H -71.8 -35.1 24.0 0.141 0.0
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 LEU A:132 A:156 33.0 0.194 H -73.8 -35.6 33.0 0.194 0.0
LEU B:132 C:156 23.0 0.135 H -74.1 -32.4 23.0 0.135 0.0
LEU C:132 B:156 27.0 0.159 H -72.2 -35.8 27.0 0.159 0.0
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 LEU A:132 A:156 33.0 0.194 H -73.8 -35.6 33.0 0.194 0.0
LEU B:132 C:156 23.0 0.135 H -74.1 -32.4 23.0 0.135 0.0
LEU C:132 B:156 26.0 0.153 H -72.1 -35.8 26.0 0.153 0.0
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 LEU A:131 A:156 38.0 0.224 H -61.8 -47.4 38.0 0.224 0.0 HOH
 3.780
 CD2
 O
LEU B:131 B:156 44.0 0.259 H -63.4 -47.4 44.0 0.259 0.0 HOH
 3.817
 CB
 O
LEU C:131 C:156 41.0 0.241 H -66.6 -47.8 41.0 0.241 0.0 HOH
 3.890
 CD2
 O
LEU D:131 D:156 41.0 0.241 H -64.4 -45.7 NA NA NA
LEU E:131 E:156 42.0 0.247 H -63.0 -45.3 NA NA NA
LEU F:131 F:156 47.0 0.276 H -62.5 -52.2 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 LEU A:131 A:156 41.0 0.241 H -64.5 -42.1 41.0 0.241 0.0 UZG
 5.061
 N
 C01
LEU B:131 B:156 49.0 0.288 H -65.0 -42.8 49.0 0.288 0.0 UZG
 5.465
 N
 C01
LEU C:131 C:156 47.0 0.276 H -63.0 -39.7 47.0 0.276 0.0 UZG
 5.394
 N
 C01
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 LEU A:152 A:156 37.0 0.218 H -65.1 -48.2 37.0 0.218 0.0 HOH
 4.936
 N
 O
LEU B:152 B:156 39.0 0.229 H -64.9 -48.1 39.0 0.229 0.0 HOH
 4.872
 N
 O
LEU C:152 C:156 36.0 0.212 H -64.8 -47.8 36.0 0.212 0.0 HOH
 5.017
 CD2
 O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 LEU A:152 A:156 46.0 0.271 H -52.6 -39.1 46.0 0.271 0.0
LEU B:152 B:156 47.0 0.276 H -52.7 -39.1 47.0 0.276 0.0
LEU C:152 C:156 53.0 0.312 H -53.1 -38.7 53.0 0.312 0.0 HOH
 6.805
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 ARG A:155 A:155 91.0 0.404 H -62.3 -42.9