Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50471035 . G A CCDS8796.1:NM_020039.3:c.598Ggc>Agc_NP_064423.2:p.200G>S Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 GLY B:200 D:200 22.0 0.293 69.6 7.3 22.0 0.293 0.0
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 GLY A:201 A:201 14.0 0.187 80.8 -16.7 14.0 0.187 0.0
GLY B:201 B:201 14.0 0.187 80.9 -16.8 14.0 0.187 0.0
GLY C:201 C:201 13.0 0.173 80.8 -16.8 13.0 0.173 0.0
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 GLY A:201 A:201 22.0 0.293 80.0 -3.2 22.0 0.293 0.0
GLY B:201 C:201 21.0 0.28 80.2 -3.3 21.0 0.28 0.0
GLY C:201 B:201 22.0 0.293 80.1 -3.3 22.0 0.293 0.0
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 GLY A:201 A:201 17.0 0.227 78.9 -7.3 17.0 0.227 0.0
GLY B:201 C:201 18.0 0.24 78.9 -7.3 18.0 0.24 0.0
GLY C:201 B:201 19.0 0.253 78.9 -7.3 19.0 0.253 0.0
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 GLY A:209 A:200 26.0 0.347 73.2 34.9 26.0 0.347 0.0
GLY B:209 B:200 27.0 0.36 73.3 34.9 27.0 0.36 0.0
GLY C:209 C:200 25.0 0.333 73.3 34.9 25.0 0.333 0.0
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 GLY A:209 A:200 27.0 0.36 90.5 -17.4 27.0 0.36 0.0
GLY B:209 B:200 28.0 0.373 90.5 -17.3 28.0 0.373 0.0
GLY C:209 C:200 27.0 0.36 90.6 -17.3 27.0 0.36 0.0
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 GLY A:190 A:200 25.0 0.333 75.6 2.6 25.0 0.333 0.0
GLY B:190 B:200 27.0 0.36 76.3 1.9 27.0 0.36 0.0
GLY C:190 C:200 26.0 0.347 77.8 -4.1 26.0 0.347 0.0
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 GLY A:190 A:200 26.0 0.347 81.9 -15.2 26.0 0.347 0.0
GLY B:190 B:200 25.0 0.333 80.2 -11.2 25.0 0.333 0.0 HOH
 6.680
 N
 O
GLY C:190 C:200 25.0 0.333 81.1 -12.0 25.0 0.333 0.0 HOH
 9.171
 CA
 O
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 GLY A:205 A:201 21.0 0.28 81.2 -10.4 21.0 0.28 0.0
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 GLY A:200 A:201 18.0 0.24 52.5 43.3 18.0 0.24 0.0
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 GLY A:188 A:201 22.0 0.293 60.4 30.5 22.0 0.293 0.0 HOH
 3.008
 N
 O
GLY B:188 B:201 21.0 0.28 59.0 33.0 21.0 0.28 0.0 HOH
 5.060
 N
 O
GLY C:188 C:201 20.0 0.267 61.3 30.4 20.0 0.267 0.0 HOH
 4.731
 N
 O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 GLY A:188 A:201 16.0 0.213 67.9 19.2 16.0 0.213 0.0
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLY A:188 A:201 25.0 0.333 61.4 29.9 25.0 0.333 0.0 HOH
 3.220
 N
 O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLY A:188 A:201 20.0 0.267 61.3 37.1 20.0 0.267 0.0 HOH
 2.736
 N
 O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLY A:188 A:201 23.0 0.307 65.1 19.8 23.0 0.307 0.0 CS
HOH
 9.809
4.273
 N
N
 CS
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 GLY A:188 A:201 22.0 0.293 81.8 -11.0 22.0 0.293 0.0
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 GLY A:177 A:201 21.0 0.28 66.4 10.7 21.0 0.28 0.0
GLY B:177 C:201 16.0 0.213 65.6 11.4 16.0 0.213 0.0
GLY C:177 B:201 23.0 0.307 68.0 10.4 23.0 0.307 0.0
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 GLY A:177 A:201 22.0 0.293 66.8 10.6 22.0 0.293 0.0
GLY B:177 C:201 20.0 0.267 65.6 11.1 20.0 0.267 0.0
GLY C:177 B:201 25.0 0.333 67.8 10.3 25.0 0.333 0.0
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 GLY A:177 A:201 20.0 0.267 66.4 10.7 20.0 0.267 0.0
GLY B:177 C:201 16.0 0.213 65.5 11.4 16.0 0.213 0.0
GLY C:177 B:201 23.0 0.307 68.0 10.4 23.0 0.307 0.0
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 GLY A:177 A:201 21.0 0.28 66.4 10.8 21.0 0.28 0.0
GLY B:177 C:201 16.0 0.213 65.5 11.5 16.0 0.213 0.0
GLY C:177 B:201 23.0 0.307 68.0 10.4 23.0 0.307 0.0
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 GLY A:176 A:201 42.0 0.56 S 83.7 102.2 42.0 0.56 0.0 HOH
 3.160
 N
 O
GLY B:176 B:201 21.0 0.28 S 90.9 179.8 21.0 0.28 0.0 HOH
 3.150
 N
 O
GLY C:176 C:201 50.0 0.667 69.3 24.2 50.0 0.667 0.0 HOH
 3.256
 N
 O
GLY D:176 D:201 31.0 0.413 S 67.5 66.3 NA NA NA
GLY E:176 E:201 52.0 0.693 93.6 56.8 NA NA NA
GLY F:176 F:201 40.0 0.533 S 75.4 48.3 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 GLY A:176 A:201 21.0 0.28 73.0 17.1 21.0 0.28 0.0
GLY B:176 B:201 27.0 0.36 72.8 13.3 27.0 0.36 0.0
GLY C:176 C:201 25.0 0.333 71.7 10.1 25.0 0.333 0.0
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 GLY A:197 A:201 49.0 0.653 S 74.0 22.2 49.0 0.653 0.0 NAG
HOH
 8.503
3.030
 CA
N
 O7
O
GLY B:197 B:201 45.0 0.6 S 73.0 22.1 45.0 0.6 0.0 NAG
HOH
 8.500
7.435
 CA
N
 O7
O
GLY C:197 C:201 48.0 0.64 S 73.8 22.0 48.0 0.64 0.0 HOH
 4.326
 N
 O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 GLY A:197 A:201 17.0 0.227 79.4 -18.0 17.0 0.227 0.0 HOH
 3.536
 O
 O
GLY B:197 B:201 26.0 0.347 70.7 31.1 26.0 0.347 0.0 HOH
 3.384
 O
 O
GLY C:197 C:201 21.0 0.28 72.3 -6.7 21.0 0.28 0.0 HOH
 2.760
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 GLY A:200 A:200 26.0 0.347 66.2 9.0