Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50471072 . G A CCDS8796.1:NM_020039.3:c.635gGt>gAt_NP_064423.2:p.212G>D Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 GLY B:212 D:212 18.0 0.24 -79.0 -166.8 18.0 0.24 0.0
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 GLY A:213 A:213 22.0 0.293 -87.6 -161.1 3.0 0.04 0.253 B:Q1XA76:0.253
GLY B:213 B:213 22.0 0.293 -87.6 -161.0 4.0 0.053 0.24 C:Q1XA76:0.24
GLY C:213 C:213 22.0 0.293 -87.5 -161.1 3.0 0.04 0.253 A:Q1XA76:0.253
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 GLY A:213 A:213 35.0 0.467 -104.1 160.5 5.0 0.067 0.4 C:Q1XA76:0.4
GLY B:213 C:213 35.0 0.467 -104.0 160.4 4.0 0.053 0.414 A:Q1XA76:0.413
GLY C:213 B:213 36.0 0.48 -104.1 160.4 4.0 0.053 0.427 B:Q1XA76:0.427
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 GLY A:213 A:213 20.0 0.267 -94.3 -162.7 4.0 0.053 0.214 C:Q1XA76:0.213
GLY B:213 C:213 20.0 0.267 -94.2 -162.8 4.0 0.053 0.214 A:Q1XA76:0.213
GLY C:213 B:213 20.0 0.267 -94.2 -162.8 5.0 0.067 0.2 B:Q1XA76:0.2
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 GLY A:221 A:212 13.0 0.173 -87.6 -121.1 3.0 0.04 0.133 C:P78348:0.133
GLY B:221 B:212 14.0 0.187 -87.5 -121.1 3.0 0.04 0.147 A:P78348:0.147
GLY C:221 C:212 13.0 0.173 -87.6 -121.2 3.0 0.04 0.133 B:P78348:0.133
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 GLY A:221 A:212 22.0 0.293 -84.6 -157.1 3.0 0.04 0.253 B:P78348:0.253
GLY B:221 B:212 23.0 0.307 -84.6 -157.1 3.0 0.04 0.267 C:P78348:0.267
GLY C:221 C:212 23.0 0.307 -84.6 -157.1 4.0 0.053 0.254 A:P78348:0.253
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 GLY A:202 A:212 23.0 0.307 -77.8 -176.1 2.0 0.027 0.28 B:P78348:0.28
GLY B:202 B:212 25.0 0.333 -107.5 163.7 0.0 0.0 0.333 C:P78348:0.333
GLY C:202 C:212 26.0 0.347 -105.4 165.5 7.0 0.093 0.254 A:P78348:0.253
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 GLY A:202 A:212 34.0 0.453 -74.5 163.7 11.0 0.147 0.306 B:P78348:0.307
 HOH
 7.714
 O
 O
GLY B:202 B:212 37.0 0.493 S -74.3 160.0 9.0 0.12 0.373 C:P78348:0.373
 HOH
 4.830
 C
 O
GLY C:202 C:212 35.0 0.467 S -73.7 161.2 8.0 0.107 0.36 A:P78348:0.36
 HOH
 7.424
 O
 O
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 GLY A:217 A:213 34.0 0.453 S -101.3 153.9 3.0 0.04 0.413 A:Q1XA76:0.413
 CL
HOH
 7.345
3.321
 O
O
 CL
O
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 GLY A:212 A:213 35.0 0.467 S -93.3 150.1 2.0 0.027 0.44 A:Q1XA76:0.44
 CL
HOH
 7.313
3.212
 O
O
 CL
O
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 GLY A:200 A:213 43.0 0.573 -85.6 148.1 7.0 0.093 0.48 C:Q1XA76:0.48
 CL
HOH
 7.036
3.905
 O
O
 CL
O
GLY B:200 B:213 41.0 0.547 -85.4 149.6 9.0 0.12 0.427 A:Q1XA76:0.427
 CL
HOH
 7.161
2.469
 O
O
 CL
O
GLY C:200 C:213 43.0 0.573 -84.8 148.5 7.0 0.093 0.48 B:Q1XA76:0.48
 CL
HOH
 7.078
4.104
 O
O
 CL
O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 GLY A:200 A:213 24.0 0.32 S -75.2 -178.4 8.0 0.107 0.213 A:Q1XA76:0.213
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLY A:200 A:213 40.0 0.533 S -72.7 154.8 40.0 0.533 0.0 HOH
 3.147
 N
 O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLY A:200 A:213 38.0 0.507 S -71.3 158.5 38.0 0.507 0.0 HOH
 4.015
 C
 O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 GLY A:200 A:213 43.0 0.573 S -74.0 142.2 9.0 0.12 0.453 A:Q1XA76:0.453
 CL
HOH
 7.392
2.804
 O
O
 CL
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 GLY A:200 A:213 35.0 0.467 S -101.2 154.0 2.0 0.027 0.44 A:Q1XA76:0.44
 CL
 7.364
 O
 CL
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 GLY A:189 A:213 29.0 0.387 -100.5 167.8 4.0 0.053 0.334 C:Q1XA76:0.333
GLY B:189 C:213 31.0 0.413 -102.8 164.7 5.0 0.067 0.346 A:Q1XA76:0.347
GLY C:189 B:213 30.0 0.4 -101.9 166.6 8.0 0.107 0.293 B:Q1XA76:0.293
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 GLY A:189 A:213 31.0 0.413 -100.5 167.5 4.0 0.053 0.36 C:Q1XA76:0.36
GLY B:189 C:213 30.0 0.4 -102.7 164.9 4.0 0.053 0.347 A:Q1XA76:0.347
GLY C:189 B:213 29.0 0.387 -102.1 166.8 7.0 0.093 0.294 B:Q1XA76:0.293
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 GLY A:189 A:213 29.0 0.387 -100.4 167.8 4.0 0.053 0.334 C:Q1XA76:0.333
GLY B:189 C:213 30.0 0.4 -102.8 164.7 5.0 0.067 0.333 A:Q1XA76:0.333
GLY C:189 B:213 30.0 0.4 -101.9 166.6 8.0 0.107 0.293 B:Q1XA76:0.293
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 GLY A:189 A:213 29.0 0.387 -100.5 167.8 4.0 0.053 0.334 C:Q1XA76:0.333
GLY B:189 C:213 31.0 0.413 -102.8 164.7 5.0 0.067 0.346 A:Q1XA76:0.347
GLY C:189 B:213 30.0 0.4 -101.9 166.6 8.0 0.107 0.293 B:Q1XA76:0.293
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 GLY A:188 A:213 42.0 0.56 S -80.8 149.3 5.0 0.067 0.493 B:Q1XA76:0.493
 CL
HOH
 7.297
3.087
 O
N
 CL
O
GLY B:188 B:213 42.0 0.56 S -76.7 150.0 6.0 0.08 0.48 C:Q1XA76:0.48
 CL
HOH
 7.439
3.012
 O
N
 CL
O
GLY C:188 C:213 40.0 0.533 S -78.2 150.8 5.0 0.067 0.466 A:Q1XA76:0.467
 CL
HOH
 7.371
3.000
 O
O
 CL
O
GLY D:188 D:213 44.0 0.587 S -77.8 147.9 NA NA NA
GLY E:188 E:213 42.0 0.56 S -80.7 146.9 NA NA NA
GLY F:188 F:213 41.0 0.547 S -78.3 148.8 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 GLY A:188 A:213 21.0 0.28 -96.3 163.6 3.0 0.04 0.24 C:Q1XA76:0.24
GLY B:188 B:213 19.0 0.253 -94.4 162.8 1.0 0.013 0.24 A:Q1XA76:0.24
GLY C:188 C:213 20.0 0.267 -96.4 163.7 0.0 0.0 0.267 B:Q1XA76:0.267
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 GLY A:209 A:213 46.0 0.613 S -82.0 143.8 6.0 0.08 0.533 B:Q1XA76:0.533
 CL
HOH
 7.115
3.264
 O
O
 CL
O
GLY B:209 B:213 47.0 0.627 S -81.3 143.9 6.0 0.08 0.547 C:Q1XA76:0.547
 CL
HOH
 7.236
2.817
 O
N
 CL
O
GLY C:209 C:213 43.0 0.573 S -81.5 143.7 5.0 0.067 0.506 A:Q1XA76:0.507
 CL
HOH
 7.188
2.957
 O
N
 CL
O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 GLY A:209 A:213 40.0 0.533 -92.6 158.7 8.0 0.107 0.426 B:Q1XA76:0.427
 HOH
 7.124
 O
 O
GLY B:209 B:213 40.0 0.533 -92.8 158.3 9.0 0.12 0.413 C:Q1XA76:0.413
GLY C:209 C:213 40.0 0.533 -92.2 158.2 8.0 0.107 0.426 A:Q1XA76:0.427
 K
CL
HOH
 8.852
7.074
6.760
 O
O
N
 K
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 GLY A:212 A:212 26.0 0.347 -76.4 172.2