Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50471078 . C A CCDS8796.1:NM_020039.3:c.641aCg>aAg_NP_064423.2:p.214T>K Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 THR B:214 D:214 68.0 0.486 T -69.8 -54.3 68.0 0.486 0.0
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 THR A:215 A:215 53.0 0.379 T -72.4 -18.9 21.0 0.15 0.229 B:Q1XA76:0.229
THR B:215 B:215 54.0 0.386 T -72.4 -18.9 21.0 0.15 0.236 C:Q1XA76:0.236
THR C:215 C:215 55.0 0.393 T -72.4 -18.9 22.0 0.157 0.236 A:Q1XA76:0.236
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 THR A:215 A:215 86.0 0.614 G -73.5 -20.2 41.0 0.293 0.321 C:Q1XA76:0.321
THR B:215 C:215 87.0 0.621 G -73.6 -20.1 42.0 0.3 0.321 A:Q1XA76:0.321
THR C:215 B:215 87.0 0.621 G -73.4 -20.2 42.0 0.3 0.321 B:Q1XA76:0.321
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 THR A:215 A:215 65.0 0.464 T -73.1 -16.5 23.0 0.164 0.3 C:Q1XA76:0.3
THR B:215 C:215 64.0 0.457 T -73.0 -16.4 22.0 0.157 0.3 A:Q1XA76:0.3
THR C:215 B:215 65.0 0.464 T -73.1 -16.4 23.0 0.164 0.3 B:Q1XA76:0.3
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 THR A:223 A:214 78.0 0.557 S -108.7 -34.9 29.0 0.207 0.35 C:P78348:0.35
THR B:223 B:214 81.0 0.579 S -108.7 -34.9 32.0 0.229 0.35 A:P78348:0.35
THR C:223 C:214 78.0 0.557 S -108.7 -34.9 30.0 0.214 0.343 B:P78348:0.343
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 THR A:223 A:214 73.0 0.521 T -73.9 -15.5 21.0 0.15 0.371 B:P78348:0.371
THR B:223 B:214 72.0 0.514 T -73.9 -15.6 22.0 0.157 0.357 C:P78348:0.357
THR C:223 C:214 73.0 0.521 T -73.9 -15.7 23.0 0.164 0.357 A:P78348:0.357
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 THR A:204 A:214 72.0 0.514 T -55.2 -44.9 26.0 0.186 0.328 B:P78348:0.329
 HOH
 4.423
 OG1
 O
THR B:204 B:214 73.0 0.521 S -57.1 -46.6 24.0 0.171 0.35 C:P78348:0.35
 HOH
 4.871
 OG1
 O
THR C:204 C:214 74.0 0.529 S -53.9 -47.9 27.0 0.193 0.336 A:P78348:0.336
 HOH
 4.900
 OG1
 O
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 THR A:204 A:214 68.0 0.486 G -66.2 -36.3 23.0 0.164 0.322 B:P78348:0.321
THR B:204 B:214 67.0 0.479 G -66.1 -34.9 24.0 0.171 0.308 C:P78348:0.307
 CL
HOH
 4.222
5.470
 O
O
 CL
O
THR C:204 C:214 67.0 0.479 G -66.8 -35.6 23.0 0.164 0.315 A:P78348:0.314
 HOH
 3.945
 O
 O
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 THR A:219 A:215 68.0 0.486 E -65.2 -34.4 24.0 0.171 0.315 A:Q1XA76:0.314
 HOH
 2.437
 O
 O
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 THR A:214 A:215 67.0 0.479 G -58.4 -33.1 25.0 0.179 0.3 A:Q1XA76:0.3
 CS
HOH
 9.274
2.610
 OG1
O
 CS
O
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 THR A:202 A:215 57.0 0.407 G -44.4 -50.4 15.0 0.107 0.3 C:Q1XA76:0.25
D:P60514:0.05
 HOH
 3.590
 CG2
 O
THR B:202 B:215 56.0 0.4 G -44.1 -49.8 15.0 0.107 0.293 A:Q1XA76:0.25
E:P60514:0.043
 HOH
 4.330
 N
 O
THR C:202 C:215 56.0 0.4 G -45.8 -50.2 16.0 0.114 0.286 F:P60514:0.057
B:Q1XA76:0.229
 HOH
 3.646
 OG1
 O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 THR A:202 A:215 59.0 0.421 E -68.0 -55.7 17.0 0.121 0.3 B:P60514:0.014
A:Q1XA76:0.279
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:202 A:215 75.0 0.536 G -56.9 -36.5 75.0 0.536 0.0 HOH
 2.991
 O
 O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:202 A:215 72.0 0.514 G -63.1 -35.9 72.0 0.514 0.0 HOH
 2.912
 O
 O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:202 A:215 70.0 0.5 G -62.5 -24.2 30.0 0.214 0.286 A:Q1XA76:0.286
 CS
PE4
HOH
 9.192
6.971
2.688
 CG2
CG2
O
 CS
C5
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 THR A:202 A:215 72.0 0.514 G -64.5 -34.2 23.0 0.164 0.35 A:Q1XA76:0.35
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 THR A:191 A:215 65.0 0.464 S -61.6 -37.9 23.0 0.164 0.3 C:Q1XA76:0.3
THR B:191 C:215 66.0 0.471 S -62.4 -37.3 20.0 0.143 0.328 A:Q1XA76:0.329
THR C:191 B:215 64.0 0.457 S -62.9 -37.6 20.0 0.143 0.314 B:Q1XA76:0.314
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 THR A:191 A:215 69.0 0.493 S -61.8 -37.9 21.0 0.15 0.343 C:Q1XA76:0.343
 CA
 4.802
 OG1
 CA
THR B:191 C:215 68.0 0.486 S -62.1 -37.1 19.0 0.136 0.35 A:Q1XA76:0.35
 CA
 4.648
 OG1
 CA
THR C:191 B:215 66.0 0.471 S -62.6 -37.3 20.0 0.143 0.328 B:Q1XA76:0.329
 CA
 4.997
 OG1
 CA
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 THR A:191 A:215 64.0 0.457 S -61.6 -38.0 21.0 0.15 0.307 C:Q1XA76:0.307
THR B:191 C:215 66.0 0.471 S -62.4 -37.2 20.0 0.143 0.328 A:Q1XA76:0.329
THR C:191 B:215 64.0 0.457 S -62.9 -37.6 20.0 0.143 0.314 B:Q1XA76:0.314
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 THR A:191 A:215 65.0 0.464 S -61.6 -37.9 23.0 0.164 0.3 C:Q1XA76:0.3
THR B:191 C:215 66.0 0.471 S -62.4 -37.3 21.0 0.15 0.321 A:Q1XA76:0.321
THR C:191 B:215 64.0 0.457 S -62.9 -37.6 20.0 0.143 0.314 B:Q1XA76:0.314
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 THR A:190 A:215 67.0 0.479 G -55.5 -33.2 25.0 0.179 0.3 B:Q1XA76:0.3
 HOH
 3.025
 O
 O
THR B:190 B:215 69.0 0.493 G -55.5 -35.4 26.0 0.186 0.307 C:Q1XA76:0.307
 HOH
 2.926
 O
 O
THR C:190 C:215 70.0 0.5 G -53.8 -35.8 27.0 0.193 0.307 A:Q1XA76:0.307
 HOH
 3.042
 O
 O
THR D:190 D:215 68.0 0.486 G -53.3 -34.2 NA NA NA
THR E:190 E:215 68.0 0.486 G -53.8 -33.9 NA NA NA
THR F:190 F:215 65.0 0.464 G -55.7 -35.1 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 THR A:190 A:215 68.0 0.486 T -45.1 -56.6 19.0 0.136 0.35 C:Q1XA76:0.35
THR B:190 B:215 58.0 0.414 G -50.1 -53.9 21.0 0.15 0.264 A:Q1XA76:0.264
THR C:190 C:215 68.0 0.486 S -45.6 -55.3 20.0 0.143 0.343 B:Q1XA76:0.343
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 THR A:211 A:215 65.0 0.464 G -57.1 -35.2 24.0 0.171 0.293 B:Q1XA76:0.293
 HOH
 2.932
 O
 O
THR B:211 B:215 66.0 0.471 G -56.6 -35.2 26.0 0.186 0.285 C:Q1XA76:0.286
 HOH
 3.476
 CG2
 O
THR C:211 C:215 65.0 0.464 G -56.6 -35.6 27.0 0.193 0.271 A:Q1XA76:0.271
 HOH
 2.969
 O
 O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 THR A:211 A:215 61.0 0.436 G -61.2 -35.9 17.0 0.121 0.315 E:P60514:0.014
B:Q1XA76:0.293
 HOH
 9.459
 OG1
 O
THR B:211 B:215 60.0 0.429 G -60.5 -36.1 18.0 0.129 0.3 F:P60514:0.021
C:Q1XA76:0.279
THR C:211 C:215 59.0 0.421 G -60.4 -35.8 10.0 0.071 0.35 D:P60514:0.071
A:Q1XA76:0.279
 K
 8.726
 OG1
 K

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 THR A:214 A:214 65.0 0.464 G -48.0 -48.0