Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50472273 . G A CCDS8796.1:NM_020039.3:c.907Gac>Aac_NP_064423.2:p.303D>N Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 ASP B:303 D:303 98.0 NA S -68.7 -40.0 98.0 NA NA
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 ASP A:302 A:302 95.0 NA S -68.2 -42.4 95.0 NA NA
ASP B:302 B:302 93.0 NA S -68.2 -42.4 93.0 NA NA
ASP C:302 C:302 94.0 NA S -68.2 -42.3 94.0 NA NA
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 ASP A:302 A:302 130.0 0.867 S -80.9 -51.5 130.0 0.867 0.0 NAG
 8.574
 O
 O7
ASP B:302 C:302 131.0 0.873 S -80.9 -51.5 131.0 0.873 0.0 NAG
 8.581
 O
 O7
ASP C:302 B:302 129.0 0.86 S -80.9 -51.5 129.0 0.86 0.0 NAG
 8.576
 O
 O7
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 ASP A:302 A:302 105.0 NA S -72.2 -25.2 105.0 NA NA
ASP B:302 C:302 105.0 NA S -72.4 -25.2 105.0 NA NA
ASP C:302 B:302 104.0 NA S -72.3 -25.1 104.0 NA NA
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 ASP A:312 A:303 89.0 0.593 S -116.9 -48.1 89.0 0.593 0.0
ASP B:312 B:303 91.0 0.607 S -116.9 -48.0 91.0 0.607 0.0
ASP C:312 C:303 88.0 0.587 S -116.9 -48.1 88.0 0.587 0.0
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 ASP A:312 A:303 146.0 0.973 S -118.5 -42.6 146.0 0.973 0.0 NAG
 9.082
 OD2
 C8
ASP B:312 B:303 145.0 0.967 S -118.5 -42.6 145.0 0.967 0.0 NAG
 9.082
 OD2
 C8
ASP C:312 C:303 146.0 0.973 S -118.6 -42.6 146.0 0.973 0.0 NAG
 9.081
 OD2
 C8
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 ASP A:293 A:303 140.0 0.933 S -80.5 -41.8 140.0 0.933 0.0
ASP B:293 B:303 145.0 0.967 S -79.5 -41.3 145.0 0.967 0.0
ASP C:293 C:303 139.0 0.927 S -81.1 -44.9 139.0 0.927 0.0
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 ASP A:293 A:303 92.0 0.613 S -75.4 -45.5 92.0 0.613 0.0
ASP B:293 B:303 151.0 1.0 S -70.5 -43.9 151.0 1.0 0.0
ASP C:293 C:303 117.0 0.78 S -82.9 -30.8 117.0 0.78 0.0 NAG
HOH
 9.665
3.083
 O
N
 C8
O
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 ASP A:306 A:302 160.0 1.0 S -77.2 -12.7 160.0 1.0 0.0 HOH
 6.186
 N
 O
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 ASP A:301 A:302 143.0 0.953 S -96.5 32.2 143.0 0.953 0.0 CS
HOH
 4.016
6.142
 CA
C
 CS
O
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 ASP A:289 A:302 88.0 NA S -84.1 -44.3 88.0 NA NA
ASP B:289 B:302 110.0 NA S -56.8 -29.8 110.0 NA NA NAG
HOH
 9.070
6.037
 O
C
 O6
O
ASP C:289 C:302 143.0 0.953 S -74.5 -41.1 143.0 0.953 0.0 NAG
HOH
 9.482
2.709
 C
OD1
 O6
O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 ASP A:289 A:302 110.0 NA 360.0 -86.7 110.0 NA NA NAG
 8.936
 O
 O7
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 ASP A:289 A:302 91.0 NA S -73.3 -67.0 91.0 NA NA NAG
HOH
 9.024
4.702
 C
O
 C8
O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 ASP A:289 A:302 142.0 0.947 S -102.9 -3.4 142.0 0.947 0.0 NAG
HOH
 8.399
2.742
 O
OD1
 C8
O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 ASP A:289 A:302 159.0 1.0 S -89.3 12.9 159.0 1.0 0.0 CS
HOH
 3.694
9.258
 OD1
O
 CS
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 ASP A:289 A:302 158.0 1.0 S -77.5 -12.9 158.0 1.0 0.0
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 ASP A:278 A:302 106.0 NA S -65.9 -45.8 106.0 NA NA
ASP B:278 C:302 98.0 NA S -65.5 -47.3 98.0 NA NA
ASP C:278 B:302 96.0 NA S -67.7 -48.3 96.0 NA NA
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 ASP A:278 A:302 106.0 NA S -66.6 -46.1 106.0 NA NA NAG
 7.777
 O
 O4
ASP B:278 C:302 93.0 NA S -65.0 -46.4 93.0 NA NA
ASP C:278 B:302 95.0 NA S -67.9 -48.4 95.0 NA NA
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 ASP A:278 A:302 107.0 NA S -65.9 -45.8 107.0 NA NA
ASP B:278 C:302 98.0 NA S -65.5 -47.3 98.0 NA NA
ASP C:278 B:302 95.0 NA S -67.7 -48.4 95.0 NA NA
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 ASP A:278 A:302 107.0 NA S -65.8 -45.9 107.0 NA NA
ASP B:278 C:302 98.0 NA S -65.6 -47.2 98.0 NA NA
ASP C:278 B:302 95.0 NA S -67.7 -48.4 95.0 NA NA
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 ASP A:277 A:302 115.0 0.767 S -63.0 -48.4 115.0 0.767 0.0 HOH
 2.722
 OD1
 O
ASP B:277 B:302 121.0 0.807 S -65.3 -37.2 121.0 0.807 0.0 NAG
HOH
 9.777
5.943
 C
N
 C6
O
ASP C:277 C:302 140.0 0.933 S -85.1 -13.9 140.0 0.933 0.0 NAG
HOH
 7.832
4.234
 O
N
 O7
O
ASP D:277 D:302 134.0 0.893 S -79.3 -30.8 NA NA NA
ASP E:277 E:302 135.0 0.9 S -86.5 -12.3 NA NA NA
ASP F:277 F:302 125.0 0.833 S -82.4 -21.8 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 ASP A:277 A:302 156.0 1.0 S -80.0 -34.0 156.0 1.0 0.0
ASP B:277 B:302 127.0 0.847 S -111.0 -34.1 127.0 0.847 0.0
ASP C:277 C:302 218.0 1.0 360.0 -40.6 218.0 1.0 0.0
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 ASP A:298 A:302 158.0 1.0 -93.3 -34.5 158.0 1.0 0.0 NAG
 9.408
 C
 O6
ASP B:298 B:302 151.0 1.0 S -93.4 -34.2 151.0 1.0 0.0 NAG
HOH
 9.407
5.622
 C
N
 O6
O
ASP C:298 C:302 159.0 1.0 S -93.1 -34.5 159.0 1.0 0.0 NAG
 9.408
 C
 O6
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 ASP A:298 A:302 151.0 1.0 S -72.8 -49.5 151.0 1.0 0.0 NAG
HOH
 9.904
9.146
 C
OD2
 C6
O
ASP B:298 B:302 152.0 1.0 S -73.2 -49.4 152.0 1.0 0.0 NAG
HOH
 9.909
9.312
 C
OD2
 C6
O
ASP C:298 C:302 164.0 1.0 S -72.7 -49.4 164.0 1.0 0.0 NAG
HOH
 9.921
9.067
 C
OD2
 C6
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 ASP A:303 A:303 148.0 0.987 S -73.1 -32.6