Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50472313 . C A CCDS8796.1:NM_020039.3:c.947aCg>aAg_NP_064423.2:p.316T>K Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 THR B:316 D:316 0.0 0.0 H -63.2 -44.8 0.0 0.0 0.0
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 THR A:315 A:315 1.0 0.007 H -61.5 -49.9 1.0 0.007 0.0
THR B:315 B:315 0.0 0.0 H -61.4 -49.9 0.0 0.0 0.0
THR C:315 C:315 0.0 0.0 H -61.5 -49.9 0.0 0.0 0.0
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 THR A:315 A:315 9.0 0.064 H -74.6 -41.2 9.0 0.064 0.0
THR B:315 C:315 9.0 0.064 H -74.7 -41.2 9.0 0.064 0.0
THR C:315 B:315 9.0 0.064 H -74.6 -41.2 9.0 0.064 0.0
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 THR A:315 A:315 3.0 0.021 H -70.6 -47.6 3.0 0.021 0.0
THR B:315 C:315 2.0 0.014 H -70.6 -47.6 2.0 0.014 0.0
THR C:315 B:315 2.0 0.014 H -70.6 -47.6 2.0 0.014 0.0
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 THR A:325 A:316 7.0 0.05 H -94.6 -49.2 7.0 0.05 0.0
THR B:325 B:316 5.0 0.036 H -94.6 -49.2 5.0 0.036 0.0
THR C:325 C:316 5.0 0.036 H -94.6 -49.2 5.0 0.036 0.0
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 THR A:325 A:316 9.0 0.064 H -80.6 -45.5 9.0 0.064 0.0
THR B:325 B:316 8.0 0.057 H -80.6 -45.6 8.0 0.057 0.0
THR C:325 C:316 8.0 0.057 H -80.7 -45.4 8.0 0.057 0.0
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 THR A:306 A:316 0.0 0.0 H -63.1 -58.0 0.0 0.0 0.0
THR B:306 B:316 1.0 0.007 H -60.9 -59.4 1.0 0.007 0.0
THR C:306 C:316 1.0 0.007 H -61.2 -58.7 1.0 0.007 0.0
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 THR A:306 A:316 2.0 0.014 H -62.9 -45.5 2.0 0.014 0.0 HOH
 7.832
 N
 O
THR B:306 B:316 1.0 0.007 H -61.4 -46.0 1.0 0.007 0.0 HOH
 7.637
 N
 O
THR C:306 C:316 1.0 0.007 H -63.5 -44.9 1.0 0.007 0.0 HOH
 7.896
 N
 O
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 THR A:319 A:315 3.0 0.021 H -70.6 -50.3 3.0 0.021 0.0 CL
 7.910
 N
 CL
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 THR A:314 A:315 3.0 0.021 H -68.2 -54.6 3.0 0.021 0.0 CL
 8.265
 N
 CL
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 THR A:302 A:315 4.0 0.029 H -60.8 -55.5 4.0 0.029 0.0 CL
 8.228
 N
 CL
THR B:302 B:315 10.0 0.071 H -59.9 -57.3 10.0 0.071 0.0 CL
 8.251
 N
 CL
THR C:302 C:315 4.0 0.029 H -58.8 -56.2 4.0 0.029 0.0 CL
HOH
 8.360
9.492
 N
O
 CL
O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 THR A:302 A:315 15.0 0.107 H -61.6 -61.1 15.0 0.107 0.0
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:302 A:315 6.0 0.043 H -65.2 -52.3 6.0 0.043 0.0 CL
HOH
 7.959
3.787
 N
CG2
 CL
O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:302 A:315 4.0 0.029 H -63.6 -49.0 4.0 0.029 0.0 CL
HOH
 7.992
3.777
 N
CG2
 CL
O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 THR A:302 A:315 5.0 0.036 H -76.4 -44.4 5.0 0.036 0.0 CS
CL
HOH
 8.715
8.432
7.714
 O
N
N
 CS
CL
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 THR A:302 A:315 3.0 0.021 H -69.8 -49.7 3.0 0.021 0.0 CL
 8.022
 N
 CL
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 THR A:291 A:315 2.0 0.014 H -59.1 -46.9 2.0 0.014 0.0
THR B:291 C:315 8.0 0.057 H -59.0 -46.1 8.0 0.057 0.0
THR C:291 B:315 2.0 0.014 H -57.6 -48.2 2.0 0.014 0.0
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 THR A:291 A:315 1.0 0.007 H -59.1 -47.1 1.0 0.007 0.0
THR B:291 C:315 7.0 0.05 H -58.7 -46.3 7.0 0.05 0.0
THR C:291 B:315 1.0 0.007 H -58.1 -48.5 1.0 0.007 0.0
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 THR A:291 A:315 2.0 0.014 H -59.1 -46.9 2.0 0.014 0.0
THR B:291 C:315 8.0 0.057 H -59.0 -46.1 8.0 0.057 0.0
THR C:291 B:315 2.0 0.014 H -57.6 -48.2 2.0 0.014 0.0
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 THR A:291 A:315 2.0 0.014 H -59.1 -46.9 2.0 0.014 0.0
THR B:291 C:315 8.0 0.057 H -59.0 -46.1 8.0 0.057 0.0
THR C:291 B:315 2.0 0.014 H -57.6 -48.2 2.0 0.014 0.0
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 THR A:290 A:315 4.0 0.029 H -62.7 -47.3 4.0 0.029 0.0 CL
HOH
 8.012
3.734
 N
CG2
 CL
O
THR B:290 B:315 6.0 0.043 H -59.9 -51.9 6.0 0.043 0.0 CL
HOH
 7.981
4.425
 N
CB
 CL
O
THR C:290 C:315 4.0 0.029 H -62.8 -45.5 4.0 0.029 0.0 CL
HOH
 7.970
3.888
 N
CG2
 CL
O
THR D:290 D:315 5.0 0.036 H -62.9 -50.4 NA NA NA
THR E:290 E:315 6.0 0.043 H -62.3 -46.1 NA NA NA
THR F:290 F:315 7.0 0.05 H -62.8 -45.0 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 THR A:290 A:315 2.0 0.014 H -76.9 -48.4 2.0 0.014 0.0
THR B:290 B:315 1.0 0.007 H -75.4 -50.9 1.0 0.007 0.0
THR C:290 C:315 17.0 0.121 H -82.9 -44.4 17.0 0.121 0.0
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 THR A:311 A:315 15.0 0.107 H -60.5 -47.6 15.0 0.107 0.0 CL
HOH
 8.029
3.740
 N
CG2
 CL
O
THR B:311 B:315 5.0 0.036 H -60.4 -47.4 5.0 0.036 0.0 CL
HOH
 8.051
4.880
 N
O
 CL
O
THR C:311 C:315 5.0 0.036 H -60.6 -48.1 5.0 0.036 0.0 CL
HOH
 7.969
3.740
 N
CG2
 CL
O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 THR A:311 A:315 5.0 0.036 H -66.3 -59.1 5.0 0.036 0.0 K
CL
 8.764
8.418
 N
N
 K
CL
THR B:311 B:315 4.0 0.029 H -67.2 -59.0 4.0 0.029 0.0 HOH
 8.127
 N
 O
THR C:311 C:315 6.0 0.043 H -66.4 -59.5 6.0 0.043 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 THR A:316 A:316 1.0 0.007 H -63.4 -48.2