Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 50473717 . G A CCDS8796.1:NM_020039.3:c.1084Gtg>Atg_NP_064423.2:p.362V>M Homo sapiens acid sensing ion channel subunit 1 (ASIC1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7rnn 2 P78348 91.46 0.0 EM
 2021-08-11 VAL B:362 D:362 98.0 NA -98.9 110.6 87.0 NA NA A:None:NA
6ave 1 Q1XA76 82.06 0.0 EM
 2018-03-21 VAL A:361 A:361 96.0 NA -125.4 109.0 96.0 NA NA
VAL B:361 B:361 93.0 NA -125.4 109.0 93.0 NA NA
VAL C:361 C:361 92.0 NA -125.4 109.0 92.0 NA NA
6vtk 1 Q1XA76 82.06 0.0 EM
 2020-03-11 VAL A:361 A:361 137.0 0.884 -121.5 134.7 134.0 0.865 0.019 B:Q1XA76:0.019
VAL B:361 C:361 136.0 0.877 -121.4 134.7 134.0 0.865 0.012 C:Q1XA76:0.013
VAL C:361 B:361 137.0 0.884 -121.5 134.7 135.0 0.871 0.013 A:Q1XA76:0.013
6vtl 1 Q1XA76 82.06 0.0 EM
 2020-03-11 VAL A:361 A:361 95.0 NA -144.9 135.4 95.0 NA NA
VAL B:361 C:361 97.0 NA -144.9 135.4 97.0 NA NA
VAL C:361 B:361 97.0 NA -144.9 135.4 97.0 NA NA
7cfs 1 P78348 91.05 0.0 EM
 2020-10-21 VAL A:371 A:362 136.0 0.877 -137.7 140.0 136.0 0.877 0.0
VAL B:371 B:362 117.0 0.755 -137.6 140.0 117.0 0.755 0.0
VAL C:371 C:362 115.0 0.742 -137.7 140.0 115.0 0.742 0.0
7cft 1 P78348 91.05 0.0 EM
 2020-10-21 VAL A:371 A:362 119.0 0.768 -97.4 160.4 26.0 0.168 0.6 D:P0DKR6:0.6
VAL B:371 B:362 117.0 0.755 -97.4 160.5 24.0 0.155 0.6 E:P0DKR6:0.6
VAL C:371 C:362 116.0 0.748 -97.3 160.4 25.0 0.161 0.587 F:P0DKR6:0.587
6l6i 1 P78348 90.0 0.0 X-RAY
 2020-11-04 VAL A:352 A:362 112.0 0.723 -78.5 113.5 112.0 0.723 0.0
VAL B:352 B:362 116.0 0.748 -97.3 105.1 116.0 0.748 0.0
VAL C:352 C:362 94.0 0.606 -93.1 107.9 94.0 0.606 0.0
6l6n 1 P78348 90.0 0.0 X-RAY
 2021-01-13 VAL A:352 A:362 109.0 0.703 -95.5 98.9 109.0 0.703 0.0 HOH
 8.333
 N
 O
VAL B:352 B:362 125.0 0.806 -96.3 96.6 125.0 0.806 0.0 HOH
 3.382
 O
 O
VAL C:352 C:362 109.0 0.703 -97.1 98.3 109.0 0.703 0.0 HOH
 7.020
 C
 O
4nyk 1 Q1XA76 81.29 0.0 X-RAY
 2014-02-12 VAL A:365 A:361 107.0 0.69 -101.6 144.1 74.0 0.477 0.213 A:Q1XA76:0.213
 CL
HOH
 6.625
8.981
 N
CA
 CL
O
3ij4 1 Q1XA76 81.29 0.0 X-RAY
 2009-11-10 VAL A:360 A:361 107.0 0.69 -110.3 143.3 77.0 0.497 0.193 A:Q1XA76:0.194
 CL
HOH
 6.244
9.184
 N
CA
 CL
O
4fz0 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 VAL A:348 A:361 86.0 NA -116.1 108.1 86.0 NA NA CL
 8.067
 N
 CL
VAL B:348 B:361 116.0 0.748 -109.9 118.3 116.0 0.748 0.0 CL
HOH
 8.342
9.871
 N
C
 CL
O
VAL C:348 C:361 120.0 0.774 -124.6 112.5 120.0 0.774 0.0 CL
HOH
 8.097
5.667
 N
CG1
 CL
O
4fz1 1 Q1XA76 81.89 0.0 X-RAY
 2012-08-01 VAL A:348 A:361 133.0 0.858 -105.9 114.1 125.0 0.806 0.052 A:Q1XA76:0.052
4ntw 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 VAL A:348 A:361 117.0 0.755 -131.4 109.5 45.0 0.29 0.465 B:G9I929:0.465
 CL
HOH
 7.975
3.040
 N
O
 CL
O
4ntx 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 VAL A:348 A:361 114.0 0.735 -138.9 105.8 45.0 0.29 0.445 B:G9I929:0.445
 CL
HOH
 7.883
4.289
 N
N
 CL
O
4nty 1 Q1XA76 81.89 0.0 X-RAY
 2014-02-19 VAL A:348 A:361 117.0 0.755 -125.1 119.9 43.0 0.277 0.478 B:G9I929:0.458
A:Q1XA76:0.045
 CL
HOH
 6.870
7.602
 N
CG1
 CL
O
6cmc 1 Q1XA76 81.89 0.0 X-RAY
 2018-08-08 VAL A:348 A:361 110.0 0.71 -139.3 143.8 80.0 0.516 0.194 A:Q1XA76:0.194
 CL
 6.720
 N
 CL
5wku 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 VAL A:337 A:361 93.0 NA -115.7 115.0 93.0 NA NA
VAL B:337 C:361 90.0 NA -115.0 113.5 90.0 NA NA
VAL C:337 B:361 88.0 NA -116.4 112.2 88.0 NA NA
5wkv 1 Q1XA76 81.52 0.0 X-RAY
 2018-03-14 VAL A:337 A:361 93.0 NA -115.8 114.6 93.0 NA NA
VAL B:337 C:361 91.0 NA -114.7 113.1 91.0 NA NA
VAL C:337 B:361 86.0 NA -116.2 112.1 86.0 NA NA
5wkx 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 VAL A:337 A:361 92.0 NA -115.7 115.0 92.0 NA NA
VAL B:337 C:361 92.0 NA -115.1 113.4 92.0 NA NA
VAL C:337 B:361 88.0 NA -116.4 112.2 88.0 NA NA
5wky 1 Q1XA76 81.52 0.0 X-RAY
 2018-08-08 VAL A:337 A:361 93.0 NA -115.7 115.0 93.0 NA NA
VAL B:337 C:361 90.0 NA -115.0 113.5 90.0 NA NA
VAL C:337 B:361 88.0 NA -116.4 112.2 88.0 NA NA
2qts 1 Q1XA76 81.48 0.0 X-RAY
 2007-09-25 VAL A:336 A:361 105.0 0.677 -112.8 123.5 66.0 0.426 0.251 C:Q1XA76:0.252
 CL
HOH
 6.570
3.163
 N
CG1
 CL
O
VAL B:336 B:361 107.0 0.69 -109.6 120.4 83.0 0.535 0.155 A:Q1XA76:0.155
 CL
HOH
 6.964
4.379
 N
O
 CL
O
VAL C:336 C:361 98.0 0.632 -119.1 132.1 76.0 0.49 0.142 B:Q1XA76:0.142
 CL
HOH
 6.637
3.519
 N
O
 CL
O
VAL D:336 D:361 106.0 0.684 -115.8 133.0 NA NA NA
VAL E:336 E:361 106.0 0.684 -111.4 127.8 NA NA NA
VAL F:336 F:361 107.0 0.69 -112.0 123.1 NA NA NA
6x9h 1 Q1XA76 81.48 0.0 X-RAY
 2020-12-30 VAL A:336 A:361 107.0 0.69 -84.1 128.5 69.0 0.445 0.245 B:Q1XA76:0.245
VAL B:336 B:361 113.0 0.729 -98.4 135.9 78.0 0.503 0.226 C:Q1XA76:0.226
VAL C:336 C:361 114.0 0.735 -101.9 138.0 101.0 0.652 0.083 A:Q1XA76:0.084
3s3w 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 VAL A:357 A:361 106.0 0.684 -101.7 110.6 72.0 0.465 0.219 C:Q1XA76:0.219
 CL
HOH
 6.686
4.433
 N
O
 CL
O
VAL B:357 B:361 107.0 0.69 -101.8 110.7 71.0 0.458 0.232 A:Q1XA76:0.232
 CL
HOH
 6.663
4.702
 N
O
 CL
O
VAL C:357 C:361 108.0 0.697 -102.1 110.8 73.0 0.471 0.226 B:Q1XA76:0.226
 CL
HOH
 6.615
4.197
 N
C
 CL
O
3s3x 1 Q1XA76 81.48 0.0 X-RAY
 2012-05-23 VAL A:357 A:361 117.0 0.755 -125.9 89.4 117.0 0.755 0.0 CL
HOH
 8.153
4.932
 N
CA
 CL
O
VAL B:357 B:361 120.0 0.774 -126.2 89.2 120.0 0.774 0.0 HOH
 8.299
 N
 O
VAL C:357 C:361 120.0 0.774 -125.9 89.2 120.0 0.774 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p78348-f1 1 P78348 91.99 0.0 VAL A:362 A:362 111.0 0.716 -86.5 95.5