Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128242 . G A CCDS8539.1:NM_000552.3:c.4342Cag>Tag_NP_000543.2:p.1448Q>* Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 GLN A:223 A:1448 143.0 0.794 H -78.5 -16.1 143.0 0.794 0.0 HOH
 2.299
 OE1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 GLN A:190 A:685 158.0 0.878 H -75.3 -25.0 158.0 0.878 0.0 HOH
 5.208
 N
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 GLN C:189 C:685 122.0 0.678 H -57.2 -74.2 116.0 0.644 0.034 B:2134245:0.033
 HOH
 5.317
 N
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLN A:189 A:685 129.0 0.717 T -87.4 29.8 129.0 0.717 0.0 HOH
 4.094
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLN A:189 A:685 138.0 0.767 H -57.2 -13.7 138.0 0.767 0.0 HOH
 4.472
 CA
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 GLN A:212 A:212 159.0 0.883 H -78.5 -28.3 159.0 0.883 0.0 HOH
 2.699
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 GLN A:188 A:685 142.0 0.789 H -70.9 -15.8 142.0 0.789 0.0 HOH
 3.318
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 GLN A:188 A:685 147.0 0.817 H -73.0 -30.2 147.0 0.817 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 GLN A:188 A:685 117.0 0.65 H -89.4 -48.2 117.0 0.65 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 GLN A:187 AAA:1448 119.0 0.661 H -53.0 -46.8 119.0 0.661 0.0 HOH
 2.635
 OE1
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLN A:186 A:685 150.0 0.833 H -63.2 -37.6 150.0 0.833 0.0 HOH
 2.681
 N
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLN A:186 A:685 157.0 0.872 T -62.0 -17.8 157.0 0.872 0.0 HOH
 8.786
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 GLN A:190 A:685 114.0 0.633 T -77.2 -62.7 114.0 0.633 0.0 HOH
 3.119
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 GLN A:186 A:1448 138.0 0.767 H -77.8 -31.1 138.0 0.767 0.0 CAC
HOH
 6.932
3.343
 NE2
O
 C2
O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 GLN C:179 A:685 145.0 0.806 H -59.1 -39.6 145.0 0.806 0.0 HOH
 4.270
 NE2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 GLN C:179 A:685 144.0 0.8 H -68.4 -39.9 144.0 0.8 0.0 HOH
 2.713
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLN A:186 A:1448 166.0 0.922 H -71.1 -29.9 166.0 0.922 0.0 HOH
 2.626
 O
 O
GLN B:186 B:1448 164.0 0.911 T -70.4 -27.9 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLN A:186 A:1448 138.0 0.767 H -85.3 -36.8 138.0 0.767 0.0
GLN C:186 C:1448 119.0 0.661 T -77.6 -37.6 NA NA NA
GLN E:186 E:1448 125.0 0.694 H -85.6 -35.4 NA NA NA
GLN G:186 G:1448 118.0 0.656 T -82.5 -40.6 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 GLN C:188 C:685 147.0 0.817 H -102.9 -6.3 147.0 0.817 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f2 1 P04275 99.93 0.0 GLN A:1248 A:1248 158.0 0.878 H -68.9 -29.0
af-p04275-f3 1 P04275 99.93 0.0 GLN A:1048 A:1048 154.0 0.856 H -67.0 -28.0
af-p04275-f6 1 P04275 100.0 0.0 GLN A:448 A:448 157.0 0.872 H -69.1 -31.1
af-p04275-f5 1 P04275 99.93 0.0 GLN A:648 A:648 159.0 0.883 H -68.5 -29.0
af-p04275-f8 1 P04275 100.0 0.0 GLN A:48 A:48 156.0 0.867 H -68.6 -30.0
af-p04275-f7 1 P04275 100.0 0.0 GLN A:248 A:248 153.0 0.85 H -69.4 -24.6
af-p04275-f4 1 P04275 99.93 0.0 GLN A:848 A:848 158.0 0.878 H -69.7 -30.0