Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128280 . T A CCDS8539.1:NM_000552.3:c.4304aAc>aTc_NP_000543.2:p.1435N>I Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ASN A:210 A:1435 3.0 0.019 -70.7 61.8 3.0 0.019 0.0 HOH
 2.910
 OD1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ASN A:177 A:672 5.0 0.031 -80.1 53.0 5.0 0.031 0.0 HOH
 2.909
 OD1
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ASN C:176 C:672 8.0 0.05 S -77.3 59.0 8.0 0.05 0.0 HOH
 3.036
 ND2
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ASN A:176 A:672 7.0 0.044 -75.7 90.7 7.0 0.044 0.0 HOH
 2.605
 OD1
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ASN A:176 A:672 7.0 0.044 -91.9 55.0 7.0 0.044 0.0 HOH
 3.711
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ASN A:199 A:199 7.0 0.044 -78.8 78.4 7.0 0.044 0.0 HOH
 2.974
 OD1
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ASN A:175 A:672 3.0 0.019 -71.4 65.2 3.0 0.019 0.0 HOH
 2.710
 OD1
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ASN A:175 A:672 8.0 0.05 -66.3 74.7 8.0 0.05 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ASN A:175 A:672 2.0 0.013 -73.7 49.8 2.0 0.013 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ASN A:174 AAA:1435 7.0 0.044 -61.1 103.8 7.0 0.044 0.0 HOH
 1.740
 HD21
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ASN A:173 A:672 5.0 0.031 -69.9 91.3 5.0 0.031 0.0 HOH
 2.725
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ASN A:173 A:672 5.0 0.031 -61.3 111.4 5.0 0.031 0.0 HOH
 3.005
 ND2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ASN A:177 A:672 9.0 0.056 -79.2 74.8 9.0 0.056 0.0 HOH
 3.062
 ND2
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ASN A:173 A:1435 6.0 0.037 -66.0 79.7 6.0 0.037 0.0 HOH
 2.854
 OD1
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ASN C:166 A:672 8.0 0.05 -73.1 78.8 8.0 0.05 0.0 HOH
 2.880
 ND2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ASN C:166 A:672 5.0 0.031 -76.5 61.0 5.0 0.031 0.0 HOH
 2.688
 OD1
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ASN A:173 A:1435 8.0 0.05 G -76.5 39.5 8.0 0.05 0.0 HOH
 2.715
 ND2
 O
ASN B:173 B:1435 8.0 0.05 G -75.8 38.4 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ASN A:173 A:1435 4.0 0.025 -81.7 85.8 4.0 0.025 0.0
ASN C:173 C:1435 5.0 0.031 -85.4 76.9 NA NA NA
ASN E:173 E:1435 2.0 0.013 -85.4 67.2 NA NA NA
ASN G:173 G:1435 7.0 0.044 -92.5 90.2 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ASN C:175 C:672 5.0 0.031 -65.8 71.4 5.0 0.031 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f2 1 P04275 99.93 0.0 ASN A:1235 A:1235 6.0 0.037 -80.2 42.1
af-p04275-f3 1 P04275 99.93 0.0 ASN A:1035 A:1035 7.0 0.044 -87.1 51.4
af-p04275-f6 1 P04275 100.0 0.0 ASN A:435 A:435 5.0 0.031 -80.8 43.7
af-p04275-f5 1 P04275 99.93 0.0 ASN A:635 A:635 7.0 0.044 -84.4 51.7
af-p04275-f8 1 P04275 100.0 0.0 ASN A:35 A:35 11.0 0.069 -86.3 116.5
af-p04275-f7 1 P04275 100.0 0.0 ASN A:235 A:235 7.0 0.044 -85.0 49.9
af-p04275-f4 1 P04275 99.93 0.0 ASN A:835 A:835 7.0 0.044 -85.6 45.4