Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128321 . G A CCDS8539.1:NM_000552.3:c.4263aaC>aaT_NP_000543.2:p.1421N>N Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ASN A:196 A:1421 19.0 0.119 -78.0 82.8 19.0 0.119 0.0 HOH
 2.859
 ND2
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ASN A:163 A:658 5.0 0.031 -73.8 90.9 5.0 0.031 0.0 OMG
OMG
HOH
 9.046
7.099
3.260
 OD1
OD1
OD1
 O3'
OP1
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ASN C:162 C:658 14.0 0.087 -72.6 -45.5 14.0 0.087 0.0 HOH
 5.875
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ASN A:162 A:658 17.0 0.106 -64.3 97.9 17.0 0.106 0.0 DT
DT
DG
DC
DC
DT
HOH
 9.012
8.531
5.619
3.581
4.465
6.625
3.601
 ND2
ND2
ND2
OD1
ND2
ND2
CB
 O4
O4
N2
O2
O2
N3
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ASN A:162 A:658 16.0 0.1 -56.4 93.4 16.0 0.1 0.0 DT
DT
DG
DC
DC
DT
HOH
 8.875
8.597
5.378
3.972
4.660
6.237
2.944
 ND2
ND2
ND2
OD1
OD1
ND2
ND2
 O4
O4
N2
O2
O2
O2
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ASN A:185 A:185 7.0 0.044 -70.6 87.9 7.0 0.044 0.0 HOH
 2.924
 ND2
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ASN A:161 A:658 13.0 0.081 -72.8 79.5 13.0 0.081 0.0 HOH
 3.455
 ND2
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ASN A:161 A:658 6.0 0.037 -75.3 73.5 2.0 0.013 0.024 C:P22030:0.025
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ASN A:161 A:658 24.0 0.15 -72.9 82.2 24.0 0.15 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ASN A:160 AAA:1421 14.0 0.087 -86.8 94.0 14.0 0.087 0.0 HOH
 2.391
 HD22
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ASN A:159 A:658 17.0 0.106 -75.8 80.9 17.0 0.106 0.0 HOH
 2.941
 ND2
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ASN A:159 A:658 6.0 0.037 -70.1 83.4 1.0 0.006 0.031 C:P22030:0.031
 HOH
 2.628
 ND2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ASN A:163 A:658 6.0 0.037 -57.4 80.6 6.0 0.037 0.0 HOH
 2.800
 ND2
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ASN A:159 A:1421 3.0 0.019 -71.1 84.6 3.0 0.019 0.0 HOH
 3.252
 ND2
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ASN C:152 A:658 7.0 0.044 -59.8 97.9 2.0 0.013 0.031 B:1890294:0.031
 HOH
 3.283
 ND2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ASN C:152 A:658 8.0 0.05 -72.4 88.5 3.0 0.019 0.031 B:None:0.031
 HOH
 3.051
 ND2
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ASN A:159 A:1421 6.0 0.037 -66.9 91.3 6.0 0.037 0.0 PEG
HOH
 3.692
3.146
 ND2
ND2
 C3
O
ASN B:159 B:1421 6.0 0.037 -66.7 89.9 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ASN A:159 A:1421 1.0 0.006 -69.6 89.1 1.0 0.006 0.0 HOH
 5.225
 OD1
 O
ASN C:159 C:1421 7.0 0.044 -70.4 89.7 NA NA NA
ASN E:159 E:1421 3.0 0.019 -68.7 95.6 NA NA NA
ASN G:159 G:1421 3.0 0.019 -67.9 86.7 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 SER C:161 C:658 4.0 0.035 -53.5 102.3 4.0 0.035 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f2 1 P04275 99.93 0.0 ASN A:1221 A:1221 19.0 0.119 -77.4 82.2
af-p04275-f3 1 P04275 99.93 0.0 ASN A:1021 A:1021 10.0 0.062 -78.6 83.3
af-p04275-f6 1 P04275 100.0 0.0 ASN A:421 A:421 11.0 0.069 -78.0 82.0
af-p04275-f5 1 P04275 99.93 0.0 ASN A:621 A:621 12.0 0.075 -78.8 85.2
af-p04275-f8 1 P04275 100.0 0.0 ASN A:21 A:21 77.0 0.481 -75.9 89.8
af-p04275-f7 1 P04275 100.0 0.0 ASN A:221 A:221 14.0 0.087 -79.3 83.9
af-p04275-f4 1 P04275 99.93 0.0 ASN A:821 A:821 13.0 0.081 -78.2 85.0