Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128335 . C A CCDS8539.1:NM_000552.3:c.4249Ggg>Tgg_NP_000543.2:p.1417G>W Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 GLY A:192 A:1417 18.0 0.24 S 81.5 172.0 18.0 0.24 0.0 HOH
 2.816
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 GLY A:159 A:654 17.0 0.227 S -96.3 -173.8 17.0 0.227 0.0 HOH
 2.769
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 GLY C:158 C:654 23.0 0.307 S 70.2 -176.8 15.0 0.2 0.107 B:2134245:0.107
 HOH
 9.416
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLY A:158 A:654 19.0 0.253 S 92.4 173.2 19.0 0.253 0.0 DC
HOH
 6.004
3.402
 O
CA
 N4
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLY A:158 A:654 20.0 0.267 S 95.6 170.4 20.0 0.267 0.0 DC
HOH
 6.085
3.358
 O
CA
 N4
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 GLY A:181 A:181 20.0 0.267 S 81.5 171.1 20.0 0.267 0.0 HOH
 2.811
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 GLY A:157 A:654 17.0 0.227 S 91.5 170.2 17.0 0.227 0.0 HOH
 3.277
 C
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 GLY A:157 A:654 17.0 0.227 S 95.7 167.3 17.0 0.227 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 GLY A:157 A:654 22.0 0.293 S 69.7 164.3 22.0 0.293 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 GLY A:156 AAA:1417 19.0 0.253 S 89.5 170.5 19.0 0.253 0.0 HOH
 2.658
 O
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLY A:155 A:654 19.0 0.253 S 87.0 169.5 19.0 0.253 0.0 HOH
 2.777
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLY A:155 A:654 16.0 0.213 S 93.4 174.3 16.0 0.213 0.0 HOH
 2.569
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 GLY A:159 A:654 21.0 0.28 S 84.8 179.0 21.0 0.28 0.0 HOH
 2.578
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 GLY A:155 A:1417 22.0 0.293 S 84.1 178.8 22.0 0.293 0.0 HOH
 3.287
 CA
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 GLY C:148 A:654 21.0 0.28 S 81.2 164.0 21.0 0.28 0.0 HOH
 3.003
 C
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 GLY C:148 A:654 19.0 0.253 S 84.8 165.4 19.0 0.253 0.0 HOH
 2.697
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLY A:155 A:1417 22.0 0.293 S 80.2 173.1 22.0 0.293 0.0 CA
HOH
 7.614
2.750
 CA
O
 CA
O
GLY B:155 B:1417 22.0 0.293 S 80.2 174.0 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLY A:155 A:1417 15.0 0.2 S 95.3 178.2 15.0 0.2 0.0 HOH
 8.648
 O
 O
GLY C:155 C:1417 18.0 0.24 S 102.2 176.8 NA NA NA
GLY E:155 E:1417 21.0 0.28 S 99.9 171.7 NA NA NA
GLY G:155 G:1417 15.0 0.2 S 89.7 176.2 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 GLY C:157 C:654 16.0 0.213 S 89.1 -171.0 16.0 0.213 0.0 HOH
 5.235
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f2 1 P04275 99.93 0.0 GLY A:1217 A:1217 17.0 0.227 S 80.4 172.7
af-p04275-f3 1 P04275 99.93 0.0 GLY A:1017 A:1017 18.0 0.24 S 81.6 175.6
af-p04275-f6 1 P04275 100.0 0.0 GLY A:417 A:417 17.0 0.227 S 79.0 176.8
af-p04275-f5 1 P04275 99.93 0.0 GLY A:617 A:617 18.0 0.24 S 80.7 175.9
af-p04275-f8 1 P04275 100.0 0.0 GLY A:17 A:17 20.0 0.267 S 89.8 159.2
af-p04275-f7 1 P04275 100.0 0.0 GLY A:217 A:217 19.0 0.253 S 73.8 177.4
af-p04275-f4 1 P04275 99.93 0.0 GLY A:817 A:817 17.0 0.227 S 82.0 175.5