Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128337 . A C CCDS8539.1:NM_000552.3:c.4247aTt>aGt_NP_000543.2:p.1416I>S Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ILE A:191 A:1416 6.0 0.034 E -119.2 112.4 6.0 0.034 0.0 EDO
HOH
 9.122
2.648
 CG2
O
 C2
O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ILE A:158 A:653 1.0 0.006 -99.5 -70.8 1.0 0.006 0.0 HOH
 3.504
 N
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ILE C:157 C:653 1.0 0.006 E -130.4 141.4 1.0 0.006 0.0 HOH
 8.685
 CD1
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ILE A:157 A:653 4.0 0.023 -125.1 111.6 4.0 0.023 0.0 DC
HOH
 8.314
2.898
 O
O
 N4
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ILE A:157 A:653 2.0 0.011 E -101.9 114.1 2.0 0.011 0.0 DC
HOH
 8.415
3.223
 O
O
 N4
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ILE A:180 A:180 3.0 0.017 E -127.3 120.8 3.0 0.017 0.0 HOH
 2.816
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ILE A:156 A:653 8.0 0.046 E -119.6 106.4 8.0 0.046 0.0 HOH
 3.188
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ILE A:156 A:653 4.0 0.023 E -119.8 114.8 4.0 0.023 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ILE A:156 A:653 2.0 0.011 E -151.7 133.5 2.0 0.011 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ILE A:155 AAA:1416 3.0 0.017 E -109.6 111.6 3.0 0.017 0.0 HOH
 3.321
 HG21
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ILE A:154 A:653 5.0 0.029 E -117.4 110.1 5.0 0.029 0.0 HOH
 2.656
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ILE A:154 A:653 3.0 0.017 E -123.3 107.2 3.0 0.017 0.0 HOH
 2.690
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ILE A:158 A:653 5.0 0.029 E -119.1 116.9 5.0 0.029 0.0 HOH
 2.382
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ILE A:154 A:1416 4.0 0.023 E -120.7 122.5 4.0 0.023 0.0 HOH
 2.604
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ILE C:147 A:653 2.0 0.011 E -132.9 119.3 2.0 0.011 0.0 HOH
 2.872
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ILE C:147 A:653 3.0 0.017 E -129.6 119.2 3.0 0.017 0.0 HOH
 2.893
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ILE A:154 A:1416 3.0 0.017 E -114.4 121.2 3.0 0.017 0.0 CA
HOH
 8.730
2.758
 O
O
 CA
O
ILE B:154 B:1416 3.0 0.017 E -113.9 119.9 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ILE A:154 A:1416 5.0 0.029 E -126.7 104.6 5.0 0.029 0.0 HOH
 9.294
 O
 O
ILE C:154 C:1416 8.0 0.046 B -119.3 96.4 NA NA NA
ILE E:154 E:1416 6.0 0.034 E -118.8 97.4 NA NA NA
ILE G:154 G:1416 5.0 0.029 E -128.3 106.1 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ILE C:156 C:653 7.0 0.04 E -97.6 99.4 7.0 0.04 0.0 HOH
 4.076
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f2 1 P04275 99.93 0.0 ILE A:1216 A:1216 4.0 0.023 E -117.3 117.4
af-p04275-f3 1 P04275 99.93 0.0 ILE A:1016 A:1016 5.0 0.029 E -119.3 118.3
af-p04275-f6 1 P04275 100.0 0.0 ILE A:416 A:416 5.0 0.029 E -116.3 117.5
af-p04275-f5 1 P04275 99.93 0.0 ILE A:616 A:616 5.0 0.029 E -117.2 117.7
af-p04275-f8 1 P04275 100.0 0.0 ILE A:16 A:16 70.0 0.4 E -107.3 131.4
af-p04275-f7 1 P04275 100.0 0.0 ILE A:216 A:216 6.0 0.034 E -115.7 119.3
af-p04275-f4 1 P04275 99.93 0.0 ILE A:816 A:816 4.0 0.023 E -117.7 116.4