Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128424 . C A CCDS8539.1:NM_000552.3:c.4160aGc>aTc_NP_000543.2:p.1387S>I Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 SER A:162 A:1387 6.0 0.052 S -149.0 178.3 6.0 0.052 0.0 HOH
 2.899
 OG
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 SER A:129 A:624 7.0 0.061 -148.7 170.0 7.0 0.061 0.0 HOH
 3.117
 OG
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 SER C:128 C:624 6.0 0.052 S -154.2 -178.2 6.0 0.052 0.0 HOH
 8.276
 OG
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 SER A:128 A:624 6.0 0.052 S -161.5 -176.7 6.0 0.052 0.0 DT
DG
DC
DC
HOH
 9.613
6.470
6.596
8.757
2.865
 C
C
O
O
OG
 C7
C6
N4
O2
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 SER A:128 A:624 5.0 0.043 S -147.4 177.7 5.0 0.043 0.0 DT
DG
DC
DC
HOH
 9.683
6.467
6.725
8.731
2.868
 C
C
O
O
OG
 O4
N1
N4
O2
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 SER A:151 A:151 7.0 0.061 S -146.9 175.4 7.0 0.061 0.0 HOH
 2.786
 OG
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 SER A:127 A:624 5.0 0.043 -147.1 -171.3 5.0 0.043 0.0 HOH
 3.346
 OG
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 SER A:127 A:624 11.0 0.096 S -154.8 -168.1 11.0 0.096 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 SER A:127 A:624 5.0 0.043 S -133.0 -167.2 5.0 0.043 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 SER A:126 AAA:1387 7.0 0.061 S -150.2 177.7 7.0 0.061 0.0 HOH
 2.691
 HB2
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 SER A:125 A:624 7.0 0.061 -148.4 -178.2 7.0 0.061 0.0 HOH
 2.992
 OG
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 SER A:125 A:624 7.0 0.061 S -143.7 -173.6 7.0 0.061 0.0 HOH
 3.148
 CB
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 SER A:129 A:624 7.0 0.061 -145.8 -175.6 7.0 0.061 0.0 HOH
 2.749
 OG
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 SER A:125 A:1387 6.0 0.052 S -131.1 -171.7 6.0 0.052 0.0 HOH
 2.931
 OG
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 SER C:118 A:624 6.0 0.052 -126.3 -171.3 6.0 0.052 0.0 HOH
 2.750
 OG
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 SER C:118 A:624 7.0 0.061 -153.1 -179.0 7.0 0.061 0.0 HOH
 2.847
 OG
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 SER A:125 A:1387 6.0 0.052 -145.2 -178.1 6.0 0.052 0.0 PEG
HOH
 8.642
2.958
 O
OG
 C3
O
SER B:125 B:1387 6.0 0.052 S -144.1 -178.8 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 SER A:125 A:1387 4.0 0.035 S -132.2 -169.1 4.0 0.035 0.0 SO4
HOH
 9.853
4.701
 CA
C
 O4
O
SER C:125 C:1387 5.0 0.043 S -134.7 -168.0 NA NA NA
SER E:125 E:1387 7.0 0.061 S -140.5 179.5 NA NA NA
SER G:125 G:1387 4.0 0.035 S -123.3 -172.6 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 SER C:127 C:624 9.0 0.078 S -168.8 -173.5 9.0 0.078 0.0 HOH
 8.982
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 SER A:1387 A:1387 7.0 0.061 S -80.4 164.9
af-p04275-f2 1 P04275 99.93 0.0 SER A:1187 A:1187 2.0 0.017 S -126.6 168.9
af-p04275-f3 1 P04275 99.93 0.0 SER A:987 A:987 2.0 0.017 S -119.9 167.1
af-p04275-f6 1 P04275 100.0 0.0 SER A:387 A:387 1.0 0.009 S -117.7 163.5
af-p04275-f5 1 P04275 99.93 0.0 SER A:587 A:587 1.0 0.009 S -119.9 168.0
af-p04275-f7 1 P04275 100.0 0.0 SER A:187 A:187 3.0 0.026 S -120.7 -179.1
af-p04275-f4 1 P04275 99.93 0.0 SER A:787 A:787 1.0 0.009 S -120.6 166.8