Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128443 . T A CCDS8539.1:NM_000552.3:c.4141Acc>Tcc_NP_000543.2:p.1381T>S Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ALA A:156 A:1381 0.0 0.0 E -114.2 117.7 0.0 0.0 0.0 HOH
 8.081
 N
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ALA A:123 A:618 0.0 0.0 E -108.8 113.7 0.0 0.0 0.0 HOH
 8.046
 N
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ALA C:122 C:618 0.0 0.0 E -116.9 105.6 0.0 0.0 0.0 HOH
 8.843
 CB
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ALA A:122 A:618 0.0 0.0 E -112.0 107.8 0.0 0.0 0.0 HOH
 7.767
 N
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ALA A:122 A:618 0.0 0.0 E -95.4 104.1 0.0 0.0 0.0 HOH
 7.774
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 THR A:145 A:145 0.0 0.0 E -110.6 117.2 0.0 0.0 0.0 HOH
 7.970
 N
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ALA A:121 A:618 0.0 0.0 E -111.8 120.7 0.0 0.0 0.0 HOH
 8.086
 CB
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ALA A:121 A:618 0.0 0.0 E -114.4 103.1 0.0 0.0 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ALA A:121 A:618 0.0 0.0 E -119.1 89.0 0.0 0.0 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ALA A:120 AAA:1381 0.0 0.0 E -102.2 110.1 0.0 0.0 0.0 HOH
 7.222
 H
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ALA A:119 A:618 0.0 0.0 E -117.8 117.0 0.0 0.0 0.0 HOH
 8.086
 N
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ALA A:119 A:618 0.0 0.0 E -117.3 107.0 0.0 0.0 0.0 HOH
 8.363
 N
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ALA A:123 A:618 0.0 0.0 E -111.5 115.1 0.0 0.0 0.0 HOH
 8.461
 CB
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ALA A:119 A:1381 0.0 0.0 E -108.8 109.4 0.0 0.0 0.0 HOH
 8.094
 N
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ALA C:112 A:618 0.0 0.0 E -112.0 109.2 0.0 0.0 0.0 HOH
 7.792
 N
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ALA C:112 A:618 0.0 0.0 E -106.3 111.2 0.0 0.0 0.0 HOH
 7.947
 N
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ALA A:119 A:1381 0.0 0.0 E -107.2 112.0 0.0 0.0 0.0 HOH
 7.846
 N
 O
ALA B:119 B:1381 0.0 0.0 E -106.9 111.4 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ALA A:119 A:1381 0.0 0.0 E -104.7 97.4 0.0 0.0 0.0
ALA C:119 C:1381 0.0 0.0 E -101.2 96.0 NA NA NA
ALA E:119 E:1381 0.0 0.0 E -113.0 93.6 NA NA NA
ALA G:119 G:1381 0.0 0.0 E -105.5 101.8 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 THR C:121 C:618 0.0 0.0 E -112.7 111.0 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 THR A:1381 A:1381 47.0 0.336 E -115.0 125.7
af-p04275-f2 1 P04275 99.93 0.0 THR A:1181 A:1181 0.0 0.0 E -121.1 116.3
af-p04275-f3 1 P04275 99.93 0.0 THR A:981 A:981 0.0 0.0 E -120.5 120.3
af-p04275-f6 1 P04275 100.0 0.0 THR A:381 A:381 0.0 0.0 E -116.2 111.8
af-p04275-f5 1 P04275 99.93 0.0 THR A:581 A:581 0.0 0.0 E -118.2 118.3
af-p04275-f7 1 P04275 100.0 0.0 THR A:181 A:181 0.0 0.0 E -126.7 113.6
af-p04275-f4 1 P04275 99.93 0.0 THR A:781 A:781 0.0 0.0 E -118.3 120.3