Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr12 | 6128446 | . | T | A | CCDS8539.1:NM_000552.3:c.4138Atc>Ttc_NP_000543.2:p.1380I>F | Homo sapiens von Willebrand factor (VWF), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5bv8 | 1 | P04275 | 99.11 | 3e-149 |
X-RAY |
2015-12-23 | ILE | A:155 | A:1380 | 0.0 | 0.0 | E | -134.0 | 134.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.504 |
N |
O |
||
| 7f49 | 1 | P04275 | 99.05 | 2e-140 |
X-RAY |
2021-07-07 | ILE | A:122 | A:617 | 0.0 | 0.0 | E | -131.9 | 130.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.553 |
N |
O |
||
| 1uex | 3 | P04275 | 99.52 | 3e-140 |
X-RAY |
2003-09-30 | ILE | C:121 | C:617 | 0.0 | 0.0 | E | -130.9 | 135.4 | 0.0 | 0.0 | 0.0 |
HOH |
9.957 |
CA |
O |
||
| 3hxo | 1 | P04275 | 99.52 | 3e-140 |
X-RAY |
2009-11-17 | ILE | A:121 | A:617 | 0.0 | 0.0 | E | -121.7 | 135.1 | 0.0 | 0.0 | 0.0 |
HOH |
7.946 |
CG1 |
O |
||
| 3hxq | 1 | P04275 | 99.52 | 3e-140 |
X-RAY |
2009-11-17 | ILE | A:121 | A:617 | 0.0 | 0.0 | E | -137.7 | 120.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.170 |
N |
O |
||
| 7eow | 1 | P04275 | 100.0 | 7e-140 |
X-RAY |
2021-07-07 | ILE | A:144 | A:144 | 0.0 | 0.0 | E | -130.5 | 135.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.325 |
N |
O |
||
| 1auq | 1 | P04275 | 99.52 | 1e-139 |
X-RAY |
1998-10-14 | ILE | A:120 | A:617 | 0.0 | 0.0 | E | -131.4 | 129.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.540 |
CG1 |
O |
||
| 1u0n | 1 | P04275 | 99.52 | 1e-139 |
X-RAY |
2005-04-19 | ILE | A:120 | A:617 | 0.0 | 0.0 | E | -135.0 | 137.5 | 0.0 | 0.0 | 0.0 | ||||||
| 1m10 | 1 | P04275 | 99.04 | 7e-139 |
X-RAY |
2002-08-28 | ILE | A:120 | A:617 | 0.0 | 0.0 | E | -143.5 | 141.0 | 0.0 | 0.0 | 0.0 | ||||||
| 7a6o | 1 | L8E853 | 99.51 | 5e-137 |
X-RAY |
2021-03-03 | ILE | A:119 | AAA:1380 | 0.0 | 0.0 | E | -131.2 | 130.1 | 0.0 | 0.0 | 0.0 |
HOH |
2.861 |
HD12 |
O |
||
| 1ijb | 1 | P04275 | 99.01 | 4e-134 |
X-RAY |
2002-07-10 | ILE | A:118 | A:617 | 0.0 | 0.0 | E | -135.0 | 136.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.475 |
N |
O |
||
| 1ijk | 1 | P04275 | 99.01 | 4e-134 |
X-RAY |
2002-07-10 | ILE | A:118 | A:617 | 0.0 | 0.0 | E | -118.8 | 138.1 | 0.0 | 0.0 | 0.0 |
HOH |
8.614 |
CA |
O |
||
| 1sq0 | 1 | P04275 | 99.01 | 5e-134 |
X-RAY |
2004-04-13 | ILE | A:122 | A:617 | 0.0 | 0.0 | E | -126.7 | 130.4 | 0.0 | 0.0 | 0.0 |
HOH |
5.781 |
CG1 |
O |
||
| 4c2a | 1 | P04275 | 98.48 | 3e-130 |
X-RAY |
2014-01-08 | ILE | A:118 | A:1380 | 0.0 | 0.0 | E | -131.5 | 132.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.428 |
N |
O |
||
| 1oak | 3 | P04275 | 99.49 | 1e-128 |
X-RAY |
1998-10-21 | ILE | C:111 | A:617 | 0.0 | 0.0 | E | -131.0 | 136.5 | 0.0 | 0.0 | 0.0 |
HOH |
5.369 |
N |
O |
||
| 1fns | 3 | P04275 | 98.97 | 2e-128 |
X-RAY |
2000-10-18 | ILE | C:111 | A:617 | 0.0 | 0.0 | E | -137.1 | 134.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.487 |
N |
O |
||
| 4c29 | 1 | P04275 | 98.48 | 4e-128 |
X-RAY |
2014-01-08 | ILE | A:118 | A:1380 | 0.0 | 0.0 | E | -126.3 | 127.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.490 |
N |
O |
||
| ILE | B:118 | B:1380 | 0.0 | 0.0 | E | -126.8 | 128.6 | NA | NA | NA | |||||||||||||
| 4c2b | 1 | P04275 | 98.48 | 4e-128 |
X-RAY |
2014-01-08 | ILE | A:118 | A:1380 | 0.0 | 0.0 | E | -120.6 | 127.0 | 0.0 | 0.0 | 0.0 | ||||||
| ILE | C:118 | C:1380 | 0.0 | 0.0 | E | -116.5 | 129.1 | NA | NA | NA | |||||||||||||
| ILE | E:118 | E:1380 | 0.0 | 0.0 | E | -118.3 | 131.2 | NA | NA | NA | |||||||||||||
| ILE | G:118 | G:1380 | 0.0 | 0.0 | E | -122.4 | 127.8 | NA | NA | NA | |||||||||||||
| 1u0o | 3 | Q8CIZ8 | 87.02 | 2e-119 |
X-RAY |
2005-04-19 | ILE | C:120 | C:617 | 0.0 | 0.0 | E | -120.1 | 132.8 | 0.0 | 0.0 | 0.0 |
HOH |
8.358 |
CD1 |
O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p04275-f1 | 1 | P04275 | 99.93 | 0.0 | ILE | A:1380 | A:1380 | 80.0 | 0.457 | E | -131.8 | 135.6 | |
| af-p04275-f2 | 1 | P04275 | 99.93 | 0.0 | ILE | A:1180 | A:1180 | 0.0 | 0.0 | E | -126.6 | 138.9 | |
| af-p04275-f3 | 1 | P04275 | 99.93 | 0.0 | ILE | A:980 | A:980 | 0.0 | 0.0 | E | -128.9 | 138.3 | |
| af-p04275-f6 | 1 | P04275 | 100.0 | 0.0 | ILE | A:380 | A:380 | 0.0 | 0.0 | E | -123.5 | 135.5 | |
| af-p04275-f5 | 1 | P04275 | 99.93 | 0.0 | ILE | A:580 | A:580 | 0.0 | 0.0 | E | -125.2 | 136.4 | |
| af-p04275-f7 | 1 | P04275 | 100.0 | 0.0 | ILE | A:180 | A:180 | 0.0 | 0.0 | E | -127.4 | 145.6 | |
| af-p04275-f4 | 1 | P04275 | 99.93 | 0.0 | ILE | A:780 | A:780 | 0.0 | 0.0 | E | -128.4 | 136.3 | |