Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128449 . G A CCDS8539.1:NM_000552.3:c.4135Cgc>Tgc_NP_000543.2:p.1379R>C Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ARG A:154 A:1379 31.0 0.138 E -129.9 123.4 31.0 0.138 0.0 HOH
 2.888
 N
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ARG A:121 A:616 15.0 0.067 E -122.1 121.3 15.0 0.067 0.0 A2M
HOH
 7.326
2.877
 NH1
N
 N1
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ARG C:120 C:616 6.0 0.027 E -109.0 124.4 6.0 0.027 0.0 HOH
 7.237
 NH2
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:120 A:616 13.0 0.058 E -113.4 118.5 13.0 0.058 0.0 HOH
 5.556
 NH1
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:120 A:616 22.0 0.098 E -107.1 138.0 22.0 0.098 0.0 HOH
 2.630
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ARG A:143 A:143 15.0 0.067 E -124.8 124.0 15.0 0.067 0.0 HOH
 2.611
 NH1
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ARG A:119 A:616 29.0 0.129 E -114.3 121.6 29.0 0.129 0.0 HOH
 3.061
 NE
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ARG A:119 A:616 8.0 0.036 E -119.5 125.8 8.0 0.036 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ARG A:119 A:616 10.0 0.044 E -138.1 141.5 10.0 0.044 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ARG A:118 AAA:1379 15.0 0.067 E -123.5 126.6 15.0 0.067 0.0 HOH
 2.128
 HH11
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:117 A:616 40.0 0.178 E -122.4 124.7 40.0 0.178 0.0 HOH
 2.746
 N
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:117 A:616 16.0 0.071 E -111.0 113.5 16.0 0.071 0.0 HOH
 5.609
 CD
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ARG A:121 A:616 9.0 0.04 E -121.5 113.0 9.0 0.04 0.0 HOH
 3.223
 N
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ARG A:117 A:1379 22.0 0.098 E -112.6 122.1 22.0 0.098 0.0 HOH
 2.901
 N
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ARG C:110 A:616 20.0 0.089 E -131.1 127.1 20.0 0.089 0.0 HOH
 2.759
 N
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ARG C:110 A:616 10.0 0.044 E -128.6 134.9 10.0 0.044 0.0 HOH
 2.923
 N
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:117 A:1379 15.0 0.067 E -124.2 119.9 15.0 0.067 0.0 HOH
 2.923
 N
 O
ARG B:117 B:1379 14.0 0.062 E -124.2 119.2 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:117 A:1379 9.0 0.04 E -130.1 108.4 9.0 0.04 0.0 HOH
 8.860
 NH2
 O
ARG C:117 C:1379 21.0 0.093 E -128.9 115.6 NA NA NA
ARG E:117 E:1379 10.0 0.044 E -126.5 100.9 NA NA NA
ARG G:117 G:1379 23.0 0.102 E -120.8 115.3 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 HIS C:119 C:616 3.0 0.015 E -137.4 109.6 3.0 0.015 0.0 HOH
 7.138
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ARG A:1379 A:1379 120.0 0.533 E -87.2 119.5
af-p04275-f2 1 P04275 99.93 0.0 ARG A:1179 A:1179 18.0 0.08 E -109.7 112.0
af-p04275-f3 1 P04275 99.93 0.0 ARG A:979 A:979 17.0 0.076 E -113.7 113.3
af-p04275-f6 1 P04275 100.0 0.0 ARG A:379 A:379 21.0 0.093 E -101.2 108.9
af-p04275-f5 1 P04275 99.93 0.0 ARG A:579 A:579 16.0 0.071 E -110.8 111.0
af-p04275-f7 1 P04275 100.0 0.0 ARG A:179 A:179 14.0 0.062 E -121.4 111.4
af-p04275-f4 1 P04275 99.93 0.0 ARG A:779 A:779 19.0 0.084 E -115.0 112.1