Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128454 . G A CCDS8539.1:NM_000552.3:c.4130gCc>gTc_NP_000543.2:p.1377A>V Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ALA A:152 A:1377 4.0 0.035 S -104.4 144.1 4.0 0.035 0.0 HOH
 3.749
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ALA A:119 A:614 5.0 0.043 S -84.3 148.6 5.0 0.043 0.0 HOH
 2.903
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ALA C:118 C:614 6.0 0.052 S -74.3 161.7 6.0 0.052 0.0 HOH
 5.339
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ALA A:118 A:614 4.0 0.035 S -121.1 161.2 4.0 0.035 0.0 HOH
 4.111
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ALA A:118 A:614 3.0 0.026 S -86.1 -180.0 3.0 0.026 0.0 HOH
 3.253
 O
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ALA A:141 A:141 5.0 0.043 S -93.2 152.8 5.0 0.043 0.0 HOH
 3.976
 CB
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ALA A:117 A:614 3.0 0.026 S -115.6 148.1 3.0 0.026 0.0 HOH
 3.563
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ALA A:117 A:614 4.0 0.035 S -113.2 148.5 4.0 0.035 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ALA A:117 A:614 8.0 0.07 S -84.0 161.9 8.0 0.07 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ALA A:116 AAA:1377 5.0 0.043 S -85.7 150.6 5.0 0.043 0.0 HOH
 3.682
 HB3
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ALA A:115 A:614 4.0 0.035 S -110.7 146.5 4.0 0.035 0.0 HOH
 3.630
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ALA A:115 A:614 3.0 0.026 S -112.1 154.9 3.0 0.026 0.0 HOH
 8.990
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ALA A:119 A:614 8.0 0.07 S -81.6 158.2 8.0 0.07 0.0 HOH
 2.573
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ALA A:115 A:1377 3.0 0.026 S -84.9 143.8 3.0 0.026 0.0 HOH
 3.637
 CB
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ALA C:108 A:614 2.0 0.017 S -117.7 143.7 2.0 0.017 0.0 HOH
 4.070
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ALA C:108 A:614 4.0 0.035 S -97.5 160.9 4.0 0.035 0.0 HOH
 3.278
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ALA A:115 A:1377 4.0 0.035 S -109.0 155.6 4.0 0.035 0.0 HOH
 4.040
 O
 O
ALA B:115 B:1377 4.0 0.035 S -110.6 154.6 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ALA A:115 A:1377 10.0 0.087 S -117.9 151.9 10.0 0.087 0.0 HOH
 7.734
 N
 O
ALA C:115 C:1377 3.0 0.026 S -114.9 141.9 NA NA NA
ALA E:115 E:1377 6.0 0.052 S -109.9 134.9 NA NA NA
ALA G:115 G:1377 3.0 0.026 S -114.7 150.1 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ALA C:117 C:614 3.0 0.026 S -109.0 159.2 3.0 0.026 0.0 HOH
 5.840
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ALA A:1377 A:1377 12.0 0.104 S -99.8 139.8
af-p04275-f2 1 P04275 99.93 0.0 ALA A:1177 A:1177 5.0 0.043 S -80.7 140.1
af-p04275-f3 1 P04275 99.93 0.0 ALA A:977 A:977 5.0 0.043 S -84.1 141.5
af-p04275-f6 1 P04275 100.0 0.0 ALA A:377 A:377 6.0 0.052 S -85.4 138.1
af-p04275-f5 1 P04275 99.93 0.0 ALA A:577 A:577 5.0 0.043 S -82.7 142.8
af-p04275-f7 1 P04275 100.0 0.0 ALA A:177 A:177 5.0 0.043 S -83.8 139.7
af-p04275-f4 1 P04275 99.93 0.0 ALA A:777 A:777 6.0 0.052 S -80.1 140.4