Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128461 . G A CCDS8539.1:NM_000552.3:c.4123Cct>Tct_NP_000543.2:p.1375P>S Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 PRO A:150 A:1375 95.0 0.655 T -68.3 -16.8 95.0 0.655 0.0 HOH
 2.680
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 PRO A:117 A:612 89.0 0.614 T -65.4 -23.0 89.0 0.614 0.0 A2M
HOH
 9.598
3.430
 CB
CB
 C2
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 PRO C:116 C:612 93.0 0.641 T -50.4 -23.8 93.0 0.641 0.0 HOH
 3.107
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 PRO A:116 A:612 84.0 0.579 T -62.9 -32.9 84.0 0.579 0.0 HOH
 4.545
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 PRO A:116 A:612 92.0 0.634 T -54.7 -34.2 92.0 0.634 0.0 HOH
 4.584
 O
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 PRO A:139 A:139 97.0 0.669 T -59.5 -26.6 97.0 0.669 0.0 HOH
 4.383
 N
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 PRO A:115 A:612 93.0 0.641 T -68.9 -5.9 93.0 0.641 0.0 HOH
 3.067
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 PRO A:115 A:612 88.0 0.607 T -51.3 -33.6 85.0 0.586 0.021 D:P07359:0.021
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 PRO A:115 A:612 81.0 0.559 T -64.8 -29.4 76.0 0.524 0.035 B:P07359:0.034
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 PRO A:114 AAA:1375 93.0 0.641 T -64.3 -22.9 93.0 0.641 0.0 HOH
 4.507
 N
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 PRO A:113 A:612 101.0 0.697 T -66.6 -17.8 101.0 0.697 0.0 HOH
 2.773
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 PRO A:113 A:612 97.0 0.669 T -53.3 -26.5 97.0 0.669 0.0 HOH
 7.769
 N
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 PRO A:117 A:612 112.0 0.772 T -69.2 9.6 112.0 0.772 0.0 HOH
 4.327
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 PRO A:113 A:1375 81.0 0.559 T -68.7 -20.1 80.0 0.552 0.007 B:P07359:0.007
 HOH
 4.591
 N
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 PRO C:106 A:612 89.0 0.614 T -59.9 -26.6 89.0 0.614 0.0 HOH
 4.380
 N
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 PRO C:106 A:612 96.0 0.662 T -70.2 -11.5 96.0 0.662 0.0 HOH
 2.370
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 PRO A:113 A:1375 91.0 0.628 T -70.9 -23.2 91.0 0.628 0.0 HOH
 4.354
 N
 O
PRO B:113 B:1375 93.0 0.641 T -70.2 -22.5 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 PRO A:113 A:1375 98.0 0.676 T -73.1 -18.0 98.0 0.676 0.0 HOH
 5.674
 CD
 O
PRO C:113 C:1375 99.0 0.683 T -73.4 -18.4 NA NA NA
PRO E:113 E:1375 102.0 0.703 T -69.6 -17.2 NA NA NA
PRO G:113 G:1375 92.0 0.634 T -72.1 -16.7 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 PRO C:115 C:612 90.0 0.621 T -57.2 -23.0 90.0 0.621 0.0 HOH
 7.709
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 PRO A:1375 A:1375 108.0 0.745 T -67.2 -21.2
af-p04275-f2 1 P04275 99.93 0.0 PRO A:1175 A:1175 93.0 0.641 T -60.9 -24.9
af-p04275-f3 1 P04275 99.93 0.0 PRO A:975 A:975 99.0 0.683 T -62.7 -21.2
af-p04275-f6 1 P04275 100.0 0.0 PRO A:375 A:375 96.0 0.662 T -60.5 -24.7
af-p04275-f5 1 P04275 99.93 0.0 PRO A:575 A:575 93.0 0.641 T -63.4 -21.7
af-p04275-f7 1 P04275 100.0 0.0 PRO A:175 A:175 94.0 0.648 T -63.6 -20.4
af-p04275-f4 1 P04275 99.93 0.0 PRO A:775 A:775 93.0 0.641 T -61.0 -24.0