Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128467 . C A CCDS8539.1:NM_000552.3:c.4117Gac>Tac_NP_000543.2:p.1373D>Y Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ASP A:148 A:1373 80.0 0.533 -99.6 7.9 80.0 0.533 0.0 HOH
 2.636
 OD1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ASP A:115 A:610 99.0 0.66 -102.9 2.7 99.0 0.66 0.0 A2M
HOH
 8.152
2.698
 N
OD2
 C2
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ASP C:114 C:610 88.0 0.587 -89.0 4.0 88.0 0.587 0.0 HOH
 3.706
 CG
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ASP A:114 A:610 68.0 0.453 -89.6 -5.9 68.0 0.453 0.0 HOH
 2.986
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ASP A:114 A:610 61.0 0.407 S -66.9 -32.6 61.0 0.407 0.0 HOH
 9.437
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ASP A:137 A:137 86.0 0.573 S -67.6 -33.3 86.0 0.573 0.0 HOH
 2.470
 OD2
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ASP A:113 A:610 78.0 0.52 S -83.5 -8.9 78.0 0.52 0.0 HOH
 4.901
 OD2
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ASP A:113 A:610 84.0 0.56 -90.2 -10.0 66.0 0.44 0.12 D:P07359:0.12
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ASP A:113 A:610 83.0 0.553 S -69.6 -66.2 46.0 0.307 0.246 B:P07359:0.247
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ASP A:112 AAA:1373 84.0 0.56 S -59.4 -37.1 84.0 0.56 0.0 HOH
 2.580
 H
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ASP A:111 A:610 81.0 0.54 S -85.5 -9.6 81.0 0.54 0.0 HOH
 2.972
 OD1
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ASP A:111 A:610 93.0 0.62 -93.8 13.4 93.0 0.62 0.0 HOH
 2.899
 OD1
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ASP A:115 A:610 90.0 0.6 S -74.3 14.5 50.0 0.333 0.267 B:P07359:0.267
 HOH
 2.737
 OD2
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ASP A:111 A:1373 77.0 0.513 S -69.0 -29.3 33.0 0.22 0.293 B:P07359:0.293
 HOH
 3.177
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ASP C:104 A:610 77.0 0.513 S -71.5 -17.9 77.0 0.513 0.0 HOH
 3.050
 OD1
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ASP C:104 A:610 101.0 0.673 S -69.6 -33.5 101.0 0.673 0.0 HOH
 2.544
 OD2
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ASP A:111 A:1373 67.0 0.447 S -89.6 -8.5 67.0 0.447 0.0 HOH
 2.301
 O
 O
ASP B:111 B:1373 68.0 0.453 S -89.0 -7.1 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ASP A:111 A:1373 76.0 0.507 S -82.9 -31.8 60.0 0.4 0.107 B:P07359:0.107
 HOH
 3.715
 O
 O
ASP C:111 C:1373 59.0 0.393 S -86.2 -27.2 NA NA NA
ASP E:111 E:1373 77.0 0.513 S -75.0 -24.2 NA NA NA
ASP G:111 G:1373 72.0 0.48 S -90.2 -26.3 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ASP C:113 C:610 88.0 0.587 S -74.1 -9.6 88.0 0.587 0.0 HOH
 3.002
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ASP A:1373 A:1373 127.0 0.847 -84.9 142.0
af-p04275-f2 1 P04275 99.93 0.0 ASP A:1173 A:1173 66.0 0.44 S -95.5 -16.4
af-p04275-f3 1 P04275 99.93 0.0 ASP A:973 A:973 78.0 0.52 S -93.7 -12.5
af-p04275-f6 1 P04275 100.0 0.0 ASP A:373 A:373 74.0 0.493 S -114.7 -3.2
af-p04275-f5 1 P04275 99.93 0.0 ASP A:573 A:573 78.0 0.52 S -88.4 -20.7
af-p04275-f7 1 P04275 100.0 0.0 ASP A:173 A:173 71.0 0.473 S -108.4 -29.2
af-p04275-f4 1 P04275 99.93 0.0 ASP A:773 A:773 70.0 0.467 S -78.8 -20.7