Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128493 . G A CCDS8539.1:NM_000552.3:c.4091aCa>aTa_NP_000543.2:p.1364T>I Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 THR A:139 A:1364 0.0 0.0 I -63.9 -42.6 0.0 0.0 0.0 HOH
 6.140
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 THR A:106 A:601 0.0 0.0 I -64.3 -44.7 0.0 0.0 0.0 A2M
OMG
A2M
HOH
 9.906
8.002
7.830
5.811
 C
O
N
N
 C2
N7
N6
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 THR C:105 C:601 0.0 0.0 I -59.2 -40.6 0.0 0.0 0.0 HOH
 7.555
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 THR A:105 A:601 0.0 0.0 I -51.6 -47.7 0.0 0.0 0.0 DT
HOH
 9.011
5.843
 O
N
 O4
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 THR A:105 A:601 0.0 0.0 I -54.3 -44.2 0.0 0.0 0.0 DT
HOH
 9.399
6.417
 O
N
 N3
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 THR A:128 A:128 0.0 0.0 I -61.2 -41.9 0.0 0.0 0.0 HOH
 5.945
 N
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 THR A:104 A:601 0.0 0.0 I -71.7 -38.4 0.0 0.0 0.0 HOH
 7.478
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 THR A:104 A:601 0.0 0.0 I -68.4 -36.2 0.0 0.0 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 THR A:104 A:601 0.0 0.0 I -61.4 -42.3 0.0 0.0 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 THR A:103 AAA:1364 0.0 0.0 I -69.3 -43.0 0.0 0.0 0.0 HOH
 8.072
 O
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 THR A:102 A:601 0.0 0.0 I -62.4 -45.3 0.0 0.0 0.0 HOH
 5.933
 N
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 THR A:102 A:601 0.0 0.0 I -62.7 -45.6 0.0 0.0 0.0 HOH
 6.561
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 THR A:106 A:601 0.0 0.0 I -59.2 -46.4 0.0 0.0 0.0 HOH
 7.001
 N
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 THR A:102 A:1364 0.0 0.0 I -61.7 -43.7 0.0 0.0 0.0 HOH
 6.266
 N
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 THR C:95 A:601 0.0 0.0 I -65.6 -42.7 0.0 0.0 0.0 HOH
 6.070
 N
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 THR C:95 A:601 0.0 0.0 I -63.6 -44.1 0.0 0.0 0.0 HOH
 6.318
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 THR A:102 A:1364 0.0 0.0 I -64.0 -39.0 0.0 0.0 0.0 HOH
 7.690
 O
 O
THR B:102 B:1364 0.0 0.0 I -64.0 -39.0 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 THR A:102 A:1364 0.0 0.0 I -74.9 -34.4 0.0 0.0 0.0
THR C:102 C:1364 0.0 0.0 I -65.3 -39.9 NA NA NA
THR E:102 E:1364 0.0 0.0 I -75.7 -18.0 NA NA NA
THR G:102 G:1364 0.0 0.0 I -62.9 -38.5 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 THR C:104 C:601 0.0 0.0 H -52.1 -50.0 0.0 0.0 0.0 HOH
 7.839
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 THR A:1364 A:1364 2.0 0.014 I -64.0 -42.6
af-p04275-f2 1 P04275 99.93 0.0 THR A:1164 A:1164 0.0 0.0 I -61.0 -41.4
af-p04275-f3 1 P04275 99.93 0.0 THR A:964 A:964 0.0 0.0 I -61.7 -41.9
af-p04275-f6 1 P04275 100.0 0.0 THR A:364 A:364 0.0 0.0 I -59.2 -40.8
af-p04275-f5 1 P04275 99.93 0.0 THR A:564 A:564 0.0 0.0 I -58.5 -40.1
af-p04275-f7 1 P04275 100.0 0.0 THR A:164 A:164 0.0 0.0 I -57.9 -39.0
af-p04275-f4 1 P04275 99.93 0.0 THR A:764 A:764 0.0 0.0 I -60.5 -41.3