Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128509 . C A CCDS8539.1:NM_000552.3:c.4075Gag>Tag_NP_000543.2:p.1359E>* Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 GLU A:134 A:1359 51.0 0.268 H -65.7 -37.1 51.0 0.268 0.0 HOH
 2.421
 OE2
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 GLU A:101 A:596 51.0 0.268 H -55.9 -49.7 51.0 0.268 0.0 A2M
OMC
A2M
OMC
HOH
 6.824
6.962
7.485
3.497
3.576
 OE1
OE1
OE2
OE2
OE2
 N1
O2
O3'
C5
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 GLU C:100 C:596 69.0 0.363 H -59.6 -42.2 69.0 0.363 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLU A:100 A:596 68.0 0.358 H -72.0 -42.4 68.0 0.358 0.0 DA
DG
DT
HOH
 8.916
6.594
7.499
2.658
 OE1
OE1
OE1
OE2
 O3'
OP1
OP2
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLU A:100 A:596 64.0 0.337 H -56.2 -45.5 64.0 0.337 0.0 DA
DG
DT
HOH
 6.901
5.043
6.894
2.787
 OE2
OE2
OE2
OE2
 O3'
OP1
OP2
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 GLU A:123 A:123 60.0 0.316 H -69.2 -37.0 60.0 0.316 0.0 HOH
 2.912
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 GLU A:99 A:596 53.0 0.279 H -65.9 -27.8 53.0 0.279 0.0 HOH
 4.102
 OE2
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 GLU A:99 A:596 57.0 0.3 H -65.5 -53.3 16.0 0.084 0.216 D:P07359:0.216
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 GLU A:99 A:596 69.0 0.363 H -66.1 -56.0 25.0 0.132 0.231 B:P07359:0.232
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 GLU A:98 AAA:1359 61.0 0.321 H -65.3 -45.3 61.0 0.321 0.0 HOH
 5.083
 OE1
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLU A:97 A:596 54.0 0.284 H -65.6 -36.7 54.0 0.284 0.0 HOH
 2.670
 OE1
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLU A:97 A:596 61.0 0.321 H -61.3 -37.3 61.0 0.321 0.0 HOH
 4.130
 CB
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 GLU A:101 A:596 73.0 0.384 H -72.3 -52.4 22.0 0.116 0.268 B:P07359:0.268
 HOH
 2.607
 OE2
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 GLU A:97 A:1359 83.0 0.437 H -65.4 -42.3 27.0 0.142 0.295 B:P07359:0.295
 HOH
 2.684
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 GLU C:90 A:596 70.0 0.368 H -62.7 -34.9 70.0 0.368 0.0 HOH
 3.145
 OE1
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 GLU C:90 A:596 70.0 0.368 H -67.5 -37.8 70.0 0.368 0.0 HOH
 2.568
 OE2
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLU A:97 A:1359 68.0 0.358 H -63.8 -42.4 68.0 0.358 0.0 HOH
 3.309
 CB
 O
GLU B:97 B:1359 77.0 0.405 H -64.4 -42.8 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLU A:97 A:1359 89.0 0.468 H -70.9 -37.0 33.0 0.174 0.294 B:P07359:0.295
GLU C:97 C:1359 86.0 0.453 H -65.1 -34.8 NA NA NA
GLU E:97 E:1359 89.0 0.468 H -73.9 -36.9 NA NA NA
GLU G:97 G:1359 83.0 0.437 H -73.8 -34.7 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 GLU C:99 C:596 50.0 0.263 H -63.2 -43.7 50.0 0.263 0.0 HOH
 6.377
 CG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 GLU A:1359 A:1359 67.0 0.353 H -71.5 -34.2
af-p04275-f2 1 P04275 99.93 0.0 GLU A:1159 A:1159 59.0 0.311 H -70.4 -39.2
af-p04275-f3 1 P04275 99.93 0.0 GLU A:959 A:959 52.0 0.274 H -70.6 -38.9
af-p04275-f6 1 P04275 100.0 0.0 GLU A:359 A:359 67.0 0.353 H -71.7 -40.4
af-p04275-f5 1 P04275 99.93 0.0 GLU A:559 A:559 71.0 0.374 H -73.0 -40.0
af-p04275-f7 1 P04275 100.0 0.0 GLU A:159 A:159 68.0 0.358 H -78.6 -37.2
af-p04275-f4 1 P04275 99.93 0.0 GLU A:759 A:759 70.0 0.368 H -69.7 -39.8