Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128548 . G A CCDS8539.1:NM_000552.3:c.4036Cag>Tag_NP_000543.2:p.1346Q>* Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 GLN A:121 A:1346 125.0 0.694 T -103.3 7.9 125.0 0.694 0.0 HOH
 2.874
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 GLN A:88 A:583 101.0 0.561 T -106.2 19.3 101.0 0.561 0.0 HOH
 2.610
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 GLN C:87 C:583 105.0 0.583 T -101.5 18.4 105.0 0.583 0.0 HOH
 8.201
 C
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLN A:87 A:583 95.0 0.528 S -103.9 10.9 95.0 0.528 0.0 HOH
 3.250
 CG
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLN A:87 A:583 96.0 0.533 T -85.2 33.8 96.0 0.533 0.0 HOH
 2.668
 NE2
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 GLN A:110 A:110 113.0 0.628 T -107.0 10.9 113.0 0.628 0.0 HOH
 2.726
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 GLN A:86 A:583 134.0 0.744 T -93.9 -1.8 134.0 0.744 0.0 HOH
 3.640
 CB
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 GLN A:86 A:583 108.0 0.6 T -98.6 12.4 103.0 0.572 0.028 D:P07359:0.028
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 GLN A:86 A:583 117.0 0.65 T -91.7 13.8 105.0 0.583 0.067 B:P07359:0.067
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 GLN A:85 AAA:1346 119.0 0.661 T -109.9 6.8 119.0 0.661 0.0 HOH
 3.156
 HA
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLN A:84 A:583 118.0 0.656 T -93.1 -0.4 118.0 0.656 0.0 HOH
 2.878
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLN A:84 A:583 110.0 0.611 T -106.4 12.4 110.0 0.611 0.0 HOH
 3.073
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 GLN A:88 A:583 131.0 0.728 H -94.0 -4.5 131.0 0.728 0.0 HOH
 2.494
 OE1
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 GLN A:84 A:1346 111.0 0.617 T -103.0 12.3 111.0 0.617 0.0 HOH
 2.378
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 GLN C:77 A:583 120.0 0.667 T -99.7 26.2 120.0 0.667 0.0 HOH
 3.627
 OE1
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 GLN C:77 A:583 121.0 0.672 T -103.1 7.0 121.0 0.672 0.0 HOH
 2.591
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLN A:84 A:1346 110.0 0.611 T -114.4 11.9 110.0 0.611 0.0 PEG
HOH
 6.485
2.795
 O
O
 C4
O
GLN B:84 B:1346 111.0 0.617 T -113.5 11.3 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLN A:84 A:1346 127.0 0.706 T -114.6 23.8 127.0 0.706 0.0
GLN C:84 C:1346 138.0 0.767 T -117.3 25.3 NA NA NA
GLN E:84 E:1346 88.0 0.489 T -116.7 26.1 NA NA NA
GLN G:84 G:1346 114.0 0.633 G -116.2 25.2 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 GLN C:86 C:583 117.0 0.65 T -104.6 9.0 117.0 0.65 0.0 HOH
 6.542
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 GLN A:1346 A:1346 111.0 0.617 T -86.8 3.5
af-p04275-f2 1 P04275 99.93 0.0 GLN A:1146 A:1146 72.0 0.4 T -99.9 4.7
af-p04275-f3 1 P04275 99.93 0.0 GLN A:946 A:946 96.0 0.533 T -94.3 7.5
af-p04275-f6 1 P04275 100.0 0.0 GLN A:346 A:346 82.0 0.456 T -93.2 6.0
af-p04275-f5 1 P04275 99.93 0.0 GLN A:546 A:546 106.0 0.589 T -95.9 6.1
af-p04275-f7 1 P04275 100.0 0.0 GLN A:146 A:146 113.0 0.628 T -87.7 7.1
af-p04275-f4 1 P04275 99.93 0.0 GLN A:746 A:746 112.0 0.622 T -98.4 6.0