Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128560 . G A CCDS8539.1:NM_000552.3:c.4024Cgc>Tgc_NP_000543.2:p.1342R>C Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ARG A:117 A:1342 121.0 0.538 H -63.0 -44.1 121.0 0.538 0.0 HOH
 2.806
 NH1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ARG A:84 A:579 119.0 0.529 H -66.7 -49.6 119.0 0.529 0.0 HOH
 7.019
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ARG C:83 C:579 95.0 0.422 H -67.6 -40.0 95.0 0.422 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:83 A:579 116.0 0.516 H -61.3 -51.5 116.0 0.516 0.0 HOH
 3.460
 NH1
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:83 A:579 124.0 0.551 H -59.2 -53.0 124.0 0.551 0.0 HOH
 2.866
 CG
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ARG A:106 A:106 123.0 0.547 H -62.8 -44.1 123.0 0.547 0.0 HOH
 3.752
 CG
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ARG A:82 A:579 117.0 0.52 H -66.3 -43.1 117.0 0.52 0.0 HOH
 2.669
 NH1
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ARG A:82 A:579 113.0 0.502 H -77.6 -50.4 104.0 0.462 0.04 D:P07359:0.04
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ARG A:82 A:579 95.0 0.422 H -60.4 -75.1 82.0 0.364 0.058 B:P07359:0.058
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ARG A:81 AAA:1342 108.0 0.48 H -60.3 -42.9 108.0 0.48 0.0 HOH
 4.862
 O
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:80 A:579 105.0 0.467 H -65.1 -42.2 105.0 0.467 0.0 HOH
 2.962
 NH1
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:80 A:579 119.0 0.529 H -66.0 -51.0 119.0 0.529 0.0 HOH
 4.045
 CB
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ARG A:84 A:579 130.0 0.578 H -63.0 -58.2 115.0 0.511 0.067 B:P07359:0.067
 HOH
 2.744
 NH1
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ARG A:80 A:1342 96.0 0.427 H -61.3 -47.3 96.0 0.427 0.0 HOH
 3.264
 NH2
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ARG C:73 A:579 124.0 0.551 H -66.1 -54.8 124.0 0.551 0.0 HOH
 3.679
 NH2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ARG C:73 A:579 125.0 0.556 H -63.3 -42.6 125.0 0.556 0.0 HOH
 3.229
 NH1
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:80 A:1342 100.0 0.444 H -65.6 -44.3 100.0 0.444 0.0 HOH
 2.734
 NH2
 O
ARG B:80 B:1342 91.0 0.404 H -65.4 -44.9 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:80 A:1342 123.0 0.547 H -70.8 -41.7 123.0 0.547 0.0 MES
 9.810
 N
 O1S
ARG C:80 C:1342 169.0 0.751 H -72.7 -39.8 NA NA NA
ARG E:80 E:1342 112.0 0.498 H -66.4 -47.0 NA NA NA
ARG G:80 G:1342 111.0 0.493 H -78.7 -43.8 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ARG C:82 C:579 130.0 0.578 H -72.1 -43.4 130.0 0.578 0.0 HOH
 8.247
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ARG A:1342 A:1342 115.0 0.511 H -62.9 -39.0
af-p04275-f2 1 P04275 99.93 0.0 ARG A:1142 A:1142 107.0 0.476 H -60.4 -46.6
af-p04275-f3 1 P04275 99.93 0.0 ARG A:942 A:942 121.0 0.538 H -58.6 -44.0
af-p04275-f6 1 P04275 100.0 0.0 ARG A:342 A:342 111.0 0.493 H -60.6 -38.6
af-p04275-f5 1 P04275 99.93 0.0 ARG A:542 A:542 117.0 0.52 H -63.0 -37.8
af-p04275-f7 1 P04275 100.0 0.0 ARG A:142 A:142 109.0 0.484 H -63.2 -32.5
af-p04275-f4 1 P04275 99.93 0.0 ARG A:742 A:742 123.0 0.547 H -60.6 -44.3