Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128574 . G A CCDS8539.1:NM_000552.3:c.4010cCg>cTg_NP_000543.2:p.1337P>L Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 PRO A:112 A:1337 11.0 0.076 H -52.1 -41.6 11.0 0.076 0.0 HOH
 3.584
 CB
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 PRO A:79 A:574 47.0 0.324 H -51.9 -40.5 47.0 0.324 0.0 HOH
 3.344
 CD
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 PRO C:78 C:574 28.0 0.193 H -51.7 -31.7 28.0 0.193 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 PRO A:78 A:574 48.0 0.331 H -47.7 -43.7 48.0 0.331 0.0 HOH
 3.351
 CD
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 PRO A:78 A:574 52.0 0.359 H -49.2 -41.4 52.0 0.359 0.0 HOH
 5.482
 O
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 PRO A:101 A:101 27.0 0.186 H -54.0 -42.3 27.0 0.186 0.0 HOH
 3.572
 CB
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 PRO A:77 A:574 10.0 0.069 H -49.4 -37.2 10.0 0.069 0.0 HOH
 3.568
 CB
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 PRO A:77 A:574 13.0 0.09 H -44.4 -49.0 13.0 0.09 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 PRO A:77 A:574 50.0 0.345 H -44.0 -47.3 50.0 0.345 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 PRO A:76 AAA:1337 24.0 0.166 H -34.9 -47.1 24.0 0.166 0.0 HOH
 3.113
 HB3
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 PRO A:75 A:574 20.0 0.138 H -52.5 -41.0 20.0 0.138 0.0 HOH
 2.766
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 PRO A:75 A:574 48.0 0.331 H -56.0 -25.0 48.0 0.331 0.0 HOH
 3.189
 CB
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 PRO A:79 A:574 32.0 0.221 H -38.9 -56.6 32.0 0.221 0.0 HOH
 3.578
 CD
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 PRO A:75 A:1337 43.0 0.297 H -43.9 -46.5 43.0 0.297 0.0 HOH
 4.026
 CB
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 PRO C:68 A:574 49.0 0.338 H -45.0 -47.0 49.0 0.338 0.0 HOH
 4.227
 CB
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 PRO C:68 A:574 45.0 0.31 H -52.8 -35.1 45.0 0.31 0.0 HOH
 3.072
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 PRO A:75 A:1337 49.0 0.338 H -50.7 -41.0 49.0 0.338 0.0 HOH
 3.401
 CB
 O
PRO B:75 B:1337 51.0 0.352 H -50.2 -41.7 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 PRO A:75 A:1337 45.0 0.31 H -54.2 -30.1 45.0 0.31 0.0 MES
HOH
 3.638
9.609
 CD
CG
 O2S
O
PRO C:75 C:1337 56.0 0.386 H -56.3 -36.9 NA NA NA
PRO E:75 E:1337 51.0 0.352 H -54.4 -39.0 NA NA NA
PRO G:75 G:1337 47.0 0.324 H -51.2 -35.1 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 PRO C:77 C:574 42.0 0.29 H -50.4 -25.2 42.0 0.29 0.0 HOH
 3.894
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 PRO A:1337 A:1337 48.0 0.331 H -54.6 -35.6
af-p04275-f2 1 P04275 99.93 0.0 PRO A:1137 A:1137 47.0 0.324 H -54.2 -33.6
af-p04275-f3 1 P04275 99.93 0.0 PRO A:937 A:937 44.0 0.303 H -52.9 -35.5
af-p04275-f6 1 P04275 100.0 0.0 PRO A:337 A:337 39.0 0.269 H -53.9 -35.2
af-p04275-f5 1 P04275 99.93 0.0 PRO A:537 A:537 39.0 0.269 H -52.7 -35.5
af-p04275-f7 1 P04275 100.0 0.0 PRO A:137 A:137 22.0 0.152 H -54.7 -40.4
af-p04275-f4 1 P04275 99.93 0.0 PRO A:737 A:737 47.0 0.324 H -53.3 -33.9