Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128593 . G A CCDS8539.1:NM_000552.3:c.3991Ctc>Ttc_NP_000543.2:p.1331L>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 LEU A:106 A:1331 17.0 0.1 T -56.5 -31.7 17.0 0.1 0.0 HOH
 2.863
 N
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 LEU A:73 A:568 20.0 0.118 T -61.2 -34.0 20.0 0.118 0.0 HOH
 2.937
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 LEU C:72 C:568 11.0 0.065 T -55.7 -25.4 11.0 0.065 0.0 HOH
 6.957
 CD1
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:72 A:568 17.0 0.1 T -66.3 -28.6 17.0 0.1 0.0 HOH
 2.849
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:72 A:568 15.0 0.088 T -56.1 -35.3 15.0 0.088 0.0 HOH
 2.506
 O
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 LEU A:95 A:95 17.0 0.1 T -55.1 -38.6 17.0 0.1 0.0 HOH
 2.777
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 LEU A:71 A:568 17.0 0.1 T -53.8 -40.2 17.0 0.1 0.0 HOH
 2.889
 N
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 LEU A:71 A:568 23.0 0.135 T -52.2 -35.1 23.0 0.135 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 LEU A:71 A:568 23.0 0.135 T -52.5 -41.0 23.0 0.135 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 LEU A:70 AAA:1331 18.0 0.106 T -51.2 -32.4 18.0 0.106 0.0 HOH
 3.101
 O
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:69 A:568 14.0 0.082 T -50.3 -37.2 14.0 0.082 0.0 HOH
 2.762
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:69 A:568 15.0 0.088 T -55.0 -36.7 15.0 0.088 0.0 HOH
 2.878
 N
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 LEU A:73 A:568 20.0 0.118 T -54.8 -45.5 20.0 0.118 0.0 HOH
 3.189
 N
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 LEU A:69 A:1331 20.0 0.118 T -55.8 -29.3 20.0 0.118 0.0 HOH
 2.949
 N
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 LEU C:62 A:568 17.0 0.1 T -55.3 -26.1 17.0 0.1 0.0 HOH
 2.993
 N
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 LEU C:62 A:568 15.0 0.088 T -52.5 -32.8 15.0 0.088 0.0 HOH
 3.024
 N
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:69 A:1331 11.0 0.065 T -58.0 -36.0 11.0 0.065 0.0 HOH
 2.949
 N
 O
LEU B:69 B:1331 9.0 0.053 T -57.4 -34.2 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:69 A:1331 21.0 0.124 T -69.0 -28.3 21.0 0.124 0.0
LEU C:69 C:1331 16.0 0.094 T -67.4 -41.1 NA NA NA
LEU E:69 E:1331 17.0 0.1 T -62.7 -43.8 NA NA NA
LEU G:69 G:1331 14.0 0.082 T -69.7 -24.1 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 LEU C:71 C:568 17.0 0.1 S -58.9 -49.7 17.0 0.1 0.0 HOH
 2.821
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 LEU A:1331 A:1331 4.0 0.024 T -59.4 -24.1
af-p04275-f2 1 P04275 99.93 0.0 LEU A:1131 A:1131 13.0 0.076 T -57.2 -27.2
af-p04275-f3 1 P04275 99.93 0.0 LEU A:931 A:931 16.0 0.094 T -57.4 -24.2
af-p04275-f6 1 P04275 100.0 0.0 LEU A:331 A:331 16.0 0.094 T -56.9 -26.2
af-p04275-f5 1 P04275 99.93 0.0 LEU A:531 A:531 16.0 0.094 T -58.9 -25.2
af-p04275-f7 1 P04275 100.0 0.0 LEU A:131 A:131 14.0 0.082 T -56.1 -18.5
af-p04275-f4 1 P04275 99.93 0.0 LEU A:731 A:731 16.0 0.094 T -58.5 -23.7