Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128610 . G A CCDS8539.1:NM_000552.3:c.3974tCc>tTc_NP_000543.2:p.1325S>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 SER A:100 A:1325 28.0 0.243 E -105.5 138.4 28.0 0.243 0.0 HOH
 2.890
 N
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 SER A:67 A:562 30.0 0.261 E -109.9 131.2 30.0 0.261 0.0 A2M
OMC
HOH
 9.192
7.805
2.937
 OG
N
N
 N6
N4
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 SER C:66 C:562 36.0 0.313 E -121.4 138.9 36.0 0.313 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 SER A:66 A:562 30.0 0.261 E -92.4 126.9 30.0 0.261 0.0 HOH
 2.876
 N
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 SER A:66 A:562 35.0 0.304 E -126.1 137.0 35.0 0.304 0.0 HOH
 4.025
 OG
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 SER A:89 A:89 42.0 0.365 E -113.5 147.9 42.0 0.365 0.0 HOH
 2.593
 OG
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 SER A:65 A:562 30.0 0.261 E -121.0 137.8 30.0 0.261 0.0 CD
HOH
 5.160
3.188
 N
O
 CD
O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 SER A:65 A:562 27.0 0.235 E -121.2 125.3 0.0 0.0 0.235 D:P07359:0.235
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 SER A:65 A:562 31.0 0.27 E -92.3 159.7 3.0 0.026 0.244 B:P07359:0.243
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 SER A:64 AAA:1325 34.0 0.296 E -101.0 124.7 34.0 0.296 0.0 HOH
 6.879
 O
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 SER A:63 A:562 44.0 0.383 E -148.7 158.9 44.0 0.383 0.0 HOH
 2.814
 OG
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 SER A:63 A:562 41.0 0.357 E -134.5 151.9 41.0 0.357 0.0 HOH
 4.336
 N
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 SER A:67 A:562 31.0 0.27 E -116.7 130.5 0.0 0.0 0.27 B:P07359:0.27
 HOH
 3.139
 OG
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 SER A:63 A:1325 34.0 0.296 E -97.7 131.8 2.0 0.017 0.279 B:P07359:0.278
 HOH
 2.344
 OG
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 SER C:56 A:562 34.0 0.296 E -119.2 137.8 34.0 0.296 0.0 HOH
 2.669
 OG
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 SER C:56 A:562 39.0 0.339 E -153.4 166.9 39.0 0.339 0.0 HOH
 2.564
 OG
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 SER A:63 A:1325 33.0 0.287 E -134.8 148.6 33.0 0.287 0.0 HOH
 3.052
 O
 O
SER B:63 B:1325 29.0 0.252 E -134.4 149.2 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 SER A:63 A:1325 32.0 0.278 E -144.0 120.3 1.0 0.009 0.269 B:P07359:0.27
SER C:63 C:1325 33.0 0.287 E -128.7 115.7 NA NA NA
SER E:63 E:1325 34.0 0.296 E -104.2 120.5 NA NA NA
SER G:63 G:1325 29.0 0.252 E -142.3 114.2 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 SER C:65 C:562 41.0 0.357 E -122.4 131.8 41.0 0.357 0.0 HOH
 3.060
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 SER A:1325 A:1325 23.0 0.2 E -133.7 130.7
af-p04275-f2 1 P04275 99.93 0.0 SER A:1125 A:1125 29.0 0.252 E -137.5 129.0
af-p04275-f3 1 P04275 99.93 0.0 SER A:925 A:925 33.0 0.287 E -132.5 129.6
af-p04275-f6 1 P04275 100.0 0.0 SER A:325 A:325 9.0 0.078 E -141.9 131.1
af-p04275-f5 1 P04275 99.93 0.0 SER A:525 A:525 23.0 0.2 E -138.5 134.6
af-p04275-f7 1 P04275 100.0 0.0 SER A:125 A:125 29.0 0.252 E -151.2 125.1
af-p04275-f4 1 P04275 99.93 0.0 SER A:725 A:725 30.0 0.261 E -137.1 130.3