Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128622 . T A CCDS8539.1:NM_000552.3:c.3962tAc>tTc_NP_000543.2:p.1321Y>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 TYR A:96 A:1321 0.0 0.0 E -122.5 131.2 0.0 0.0 0.0 HOH
 2.886
 OH
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 TYR A:63 A:558 0.0 0.0 E -116.4 128.3 0.0 0.0 0.0 OMC
HOH
 9.660
2.686
 C
OH
 N4
O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 TYR C:62 C:558 1.0 0.004 E -106.4 148.1 1.0 0.004 0.0 HOH
 6.540
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 TYR A:62 A:558 0.0 0.0 E -121.5 134.6 0.0 0.0 0.0 HOH
 2.648
 OH
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 TYR A:62 A:558 1.0 0.004 E -120.0 115.5 1.0 0.004 0.0 HOH
 2.819
 OH
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 TYR A:85 A:85 1.0 0.004 E -116.8 133.9 1.0 0.004 0.0 HOH
 2.837
 OH
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 TYR A:61 A:558 0.0 0.0 E -120.0 149.5 0.0 0.0 0.0 CD
HOH
 7.728
2.641
 C
OH
 CD
O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 TYR A:61 A:558 1.0 0.004 E -128.1 141.0 1.0 0.004 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 TYR A:61 A:558 1.0 0.004 E -127.7 175.8 1.0 0.004 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 TYR A:60 AAA:1321 1.0 0.004 E -118.6 128.0 1.0 0.004 0.0 HOH
 2.723
 OH
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 TYR A:59 A:558 1.0 0.004 E -116.6 138.5 1.0 0.004 0.0 HOH
 2.710
 OH
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 TYR A:59 A:558 1.0 0.004 E -113.1 138.3 1.0 0.004 0.0 HOH
 2.291
 OH
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 TYR A:63 A:558 0.0 0.0 E -136.2 125.6 0.0 0.0 0.0 HOH
 2.772
 OH
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 TYR A:59 A:1321 1.0 0.004 E -125.6 130.9 1.0 0.004 0.0 HOH
 3.570
 CB
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 TYR C:52 A:558 1.0 0.004 E -124.8 131.8 1.0 0.004 0.0 HOH
 4.677
 CE2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 TYR C:52 A:558 1.0 0.004 E -121.1 135.6 1.0 0.004 0.0 HOH
 2.746
 OH
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 TYR A:59 A:1321 1.0 0.004 E -120.9 131.7 1.0 0.004 0.0 HOH
 3.130
 OH
 O
TYR B:59 B:1321 1.0 0.004 E -120.3 132.0 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 TYR A:59 A:1321 0.0 0.0 E -119.0 146.4 0.0 0.0 0.0
TYR C:59 C:1321 0.0 0.0 E -121.6 144.0 NA NA NA
TYR E:59 E:1321 1.0 0.004 E -129.3 148.9 NA NA NA
TYR G:59 G:1321 0.0 0.0 E -128.5 143.8 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 TYR C:61 C:558 1.0 0.004 E -115.9 152.3 1.0 0.004 0.0 HOH
 7.565
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 TYR A:1321 A:1321 0.0 0.0 E -136.8 137.2
af-p04275-f2 1 P04275 99.93 0.0 TYR A:1121 A:1121 0.0 0.0 E -134.3 136.7
af-p04275-f3 1 P04275 99.93 0.0 TYR A:921 A:921 0.0 0.0 E -134.9 135.7
af-p04275-f6 1 P04275 100.0 0.0 TYR A:321 A:321 0.0 0.0 E -133.9 135.6
af-p04275-f5 1 P04275 99.93 0.0 TYR A:521 A:521 0.0 0.0 E -134.3 136.0
af-p04275-f7 1 P04275 100.0 0.0 TYR A:121 A:121 0.0 0.0 E -137.5 132.6
af-p04275-f4 1 P04275 99.93 0.0 TYR A:721 A:721 0.0 0.0 E -132.8 136.1