Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128641 . G A CCDS8539.1:NM_000552.3:c.3943Cgc>Tgc_NP_000543.2:p.1315R>C Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ARG A:90 A:1315 15.0 0.067 E -102.0 147.5 15.0 0.067 0.0 HOH
 2.922
 NH1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ARG A:57 A:552 22.0 0.098 E -96.8 142.6 22.0 0.098 0.0 HOH
 3.565
 CA
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ARG C:56 C:552 13.0 0.058 E -89.1 149.3 13.0 0.058 0.0 HOH
 3.796
 NH1
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:56 A:552 10.0 0.044 E -100.9 139.5 10.0 0.044 0.0 HOH
 3.448
 CA
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:56 A:552 9.0 0.04 E -96.1 146.5 9.0 0.04 0.0 HOH
 3.267
 CA
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ARG A:79 A:79 7.0 0.031 E -105.8 143.7 7.0 0.031 0.0 HOH
 3.225
 NH2
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ARG A:55 A:552 6.0 0.027 E -106.6 145.4 6.0 0.027 0.0 HOH
 4.430
 NH1
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ARG A:55 A:552 15.0 0.067 E -112.7 119.4 15.0 0.067 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ARG A:55 A:552 16.0 0.071 E -99.4 160.2 16.0 0.071 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ARG A:54 AAA:1315 12.0 0.053 E -95.3 137.7 12.0 0.053 0.0 HOH
 2.600
 HA
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:53 A:552 4.0 0.018 E -99.5 149.7 4.0 0.018 0.0 HOH
 3.418
 CA
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:53 A:552 7.0 0.031 E -108.9 145.6 7.0 0.031 0.0 HOH
 3.666
 CA
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ARG A:57 A:552 32.0 0.142 E -113.7 135.6 32.0 0.142 0.0 HOH
 3.646
 NH2
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ARG A:53 A:1315 27.0 0.12 E -113.7 146.4 27.0 0.12 0.0 HOH
 2.930
 NH1
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ARG C:46 A:552 19.0 0.084 E -94.8 149.0 19.0 0.084 0.0 HOH
 4.256
 NH2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ARG C:46 A:552 14.0 0.062 E -97.7 152.7 14.0 0.062 0.0 HOH
 2.568
 NH2
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:53 A:1315 7.0 0.031 E -104.8 144.1 7.0 0.031 0.0 HOH
 3.760
 CA
 O
ARG B:53 B:1315 5.0 0.022 E -105.4 143.2 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:53 A:1315 19.0 0.084 E -101.2 142.6 19.0 0.084 0.0 HOH
 7.164
 NH1
 O
ARG C:53 C:1315 8.0 0.036 E -97.6 139.9 NA NA NA
ARG E:53 E:1315 6.0 0.027 E -104.3 139.3 NA NA NA
ARG G:53 G:1315 22.0 0.098 E -104.0 138.9 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ARG C:55 C:552 8.0 0.036 E -113.0 133.3 8.0 0.036 0.0 HOH
 3.728
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ARG A:1315 A:1315 25.0 0.111 E -88.0 138.9
af-p04275-f2 1 P04275 99.93 0.0 ARG A:1115 A:1115 11.0 0.049 E -93.0 137.4
af-p04275-f3 1 P04275 99.93 0.0 ARG A:915 A:915 15.0 0.067 E -95.7 137.3
af-p04275-f6 1 P04275 100.0 0.0 ARG A:315 A:315 12.0 0.053 E -90.4 130.1
af-p04275-f5 1 P04275 99.93 0.0 ARG A:515 A:515 12.0 0.053 E -90.4 134.4
af-p04275-f7 1 P04275 100.0 0.0 ARG A:115 A:115 10.0 0.044 E -91.6 132.7
af-p04275-f4 1 P04275 99.93 0.0 ARG A:715 A:715 20.0 0.089 E -94.3 137.8