Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128645 . C A CCDS8539.1:NM_000552.3:c.3939tgG>tgT_NP_000543.2:p.1313W>C Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 TRP A:88 A:1313 56.0 0.22 S -127.9 -106.3 56.0 0.22 0.0 HOH
 2.911
 NE1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 TRP A:55 A:550 60.0 0.235 S -123.7 -114.9 60.0 0.235 0.0 HOH
 3.999
 CD1
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 TRP C:54 C:550 65.0 0.255 S -128.3 -83.7 65.0 0.255 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 TRP A:54 A:550 47.0 0.184 S -123.5 -106.4 47.0 0.184 0.0 HOH
 3.416
 NE1
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 TRP A:54 A:550 61.0 0.239 S -147.8 -101.7 61.0 0.239 0.0 HOH
 3.300
 CZ2
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 TRP A:77 A:77 66.0 0.259 S -124.0 -105.7 11.0 0.043 0.216 B:None:0.216
 HOH
 2.913
 NE1
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 TRP A:53 A:550 57.0 0.224 S -126.4 -104.9 57.0 0.224 0.0 HOH
 3.978
 CZ2
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 TRP A:53 A:550 34.0 0.133 S -149.8 -108.9 34.0 0.133 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 TRP A:53 A:550 69.0 0.271 T -127.7 -54.1 34.0 0.133 0.138 B:P07359:0.137
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 TRP A:52 AAA:1313 61.0 0.239 S -115.1 -108.1 27.0 0.106 0.133 B:None:0.133
 HOH
 2.770
 HD1
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 TRP A:51 A:550 57.0 0.224 S -129.3 -105.7 57.0 0.224 0.0 HOH
 2.863
 NE1
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 TRP A:51 A:550 69.0 0.271 S -82.4 -104.5 69.0 0.271 0.0 HOH
 5.765
 CH2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 TRP A:55 A:550 85.0 0.333 T -74.5 -47.8 25.0 0.098 0.235 B:P07359:0.235
 HOH
 5.030
 N
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 TRP A:51 A:1313 110.0 0.431 S -74.3 -34.8 50.0 0.196 0.235 B:P07359:0.235
 HOH
 2.803
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 TRP C:44 A:550 57.0 0.224 S -130.3 -106.8 57.0 0.224 0.0 HOH
 5.664
 CZ2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 TRP C:44 A:550 57.0 0.224 S -125.1 -101.2 57.0 0.224 0.0 HOH
 3.353
 CE2
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 TRP A:51 A:1313 55.0 0.216 S -130.4 -94.7 55.0 0.216 0.0 HOH
 3.361
 CB
 O
TRP B:51 B:1313 52.0 0.204 S -128.5 -96.1 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 TRP A:51 A:1313 41.0 0.161 S -103.5 -90.4 41.0 0.161 0.0 MES
HOH
 7.198
6.477
 NE1
NE1
 O1
O
TRP C:51 C:1313 53.0 0.208 S -119.5 -84.6 NA NA NA
TRP E:51 E:1313 43.0 0.169 S -109.0 -95.3 NA NA NA
TRP G:51 G:1313 50.0 0.196 S -111.6 -91.5 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ARG C:53 C:550 73.0 0.324 S -109.6 -99.1 73.0 0.324 0.0 HOH
 6.821
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 TRP A:1313 A:1313 60.0 0.235 S -116.4 -89.7
af-p04275-f2 1 P04275 99.93 0.0 TRP A:1113 A:1113 55.0 0.216 S -109.9 -87.7
af-p04275-f3 1 P04275 99.93 0.0 TRP A:913 A:913 55.0 0.216 S -113.9 -84.3
af-p04275-f6 1 P04275 100.0 0.0 TRP A:313 A:313 37.0 0.145 S -112.3 -84.6
af-p04275-f5 1 P04275 99.93 0.0 TRP A:513 A:513 53.0 0.208 S -107.7 -84.6
af-p04275-f7 1 P04275 100.0 0.0 TRP A:113 A:113 49.0 0.192 S -100.0 -101.4
af-p04275-f4 1 P04275 99.93 0.0 TRP A:713 A:713 51.0 0.2 S -103.6 -88.7