Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128653 . G A CCDS8539.1:NM_000552.3:c.3931Cag>Tag_NP_000543.2:p.1311Q>* Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 GLN A:86 A:1311 72.0 0.4 T -59.8 -23.6 72.0 0.4 0.0 HOH
 2.757
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 GLN A:53 A:548 71.0 0.394 T -63.3 -21.6 71.0 0.394 0.0 HOH
 4.352
 OE1
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 GLN C:52 C:548 32.0 0.178 T -76.6 -11.4 32.0 0.178 0.0 HOH
 5.122
 OE1
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLN A:52 A:548 51.0 0.283 T -62.1 -23.7 51.0 0.283 0.0 HOH
 2.766
 NE2
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLN A:52 A:548 35.0 0.194 T -61.7 -9.3 35.0 0.194 0.0 HOH
 3.152
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 GLN A:75 A:75 39.0 0.217 T -61.0 -25.3 39.0 0.217 0.0 HOH
 2.860
 NE2
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 GLN A:51 A:548 57.0 0.317 T -56.3 -27.9 57.0 0.317 0.0 HOH
 2.906
 NE2
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 GLN A:51 A:548 48.0 0.267 T -49.0 -26.4 41.0 0.228 0.039 D:P07359:0.039
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 GLN A:51 A:548 55.0 0.306 T -75.7 11.1 43.0 0.239 0.067 B:P07359:0.067
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 GLN A:50 AAA:1311 55.0 0.306 T -56.5 -23.1 55.0 0.306 0.0 HOH
 2.336
 HB3
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLN A:49 A:548 59.0 0.328 T -63.4 -23.7 59.0 0.328 0.0 HOH
 2.621
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLN A:49 A:548 65.0 0.361 S -42.1 -15.3 65.0 0.361 0.0 HOH
 3.863
 NE2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 GLN A:53 A:548 54.0 0.3 S -96.8 153.5 54.0 0.3 0.0 HOH
 2.719
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 GLN A:49 A:1311 26.0 0.144 S 55.4 22.1 26.0 0.144 0.0 HOH
 4.337
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 GLN C:42 A:548 48.0 0.267 T -67.4 -11.6 48.0 0.267 0.0 HOH
 3.251
 N
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 GLN C:42 A:548 55.0 0.306 T -59.9 -26.4 55.0 0.306 0.0 HOH
 3.187
 N
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLN A:49 A:1311 37.0 0.206 T -66.8 -18.9 37.0 0.206 0.0 HOH
 4.144
 NE2
 O
GLN B:49 B:1311 30.0 0.167 T -65.5 -21.2 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLN A:49 A:1311 92.0 0.511 S -70.5 -28.8 85.0 0.472 0.039 B:P07359:0.039
 MES
HOH
 8.070
6.851
 N
O
 C2
O
GLN C:49 C:1311 52.0 0.289 S -70.7 -24.3 NA NA NA
GLN E:49 E:1311 52.0 0.289 S -68.1 -27.8 NA NA NA
GLN G:49 G:1311 95.0 0.528 S -73.8 -21.5 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 GLN C:51 C:548 72.0 0.4 S -64.6 -23.8 72.0 0.4 0.0 HOH
 2.798
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 GLN A:1311 A:1311 69.0 0.383 T -58.9 -15.5
af-p04275-f2 1 P04275 99.93 0.0 GLN A:1111 A:1111 67.0 0.372 S -59.2 -22.7
af-p04275-f3 1 P04275 99.93 0.0 GLN A:911 A:911 79.0 0.439 S -61.1 -14.5
af-p04275-f6 1 P04275 100.0 0.0 GLN A:311 A:311 65.0 0.361 S -61.8 -17.8
af-p04275-f5 1 P04275 99.93 0.0 GLN A:511 A:511 61.0 0.339 S -62.0 -15.3
af-p04275-f7 1 P04275 100.0 0.0 GLN A:111 A:111 36.0 0.2 S -65.9 -27.5
af-p04275-f4 1 P04275 99.93 0.0 GLN A:711 A:711 74.0 0.411 S -60.6 -19.2