Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128656 . A C CCDS8539.1:NM_000552.3:c.3928Tcc>Gcc_NP_000543.2:p.1310S>A Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 SER A:85 A:1310 47.0 0.409 S -178.4 149.6 47.0 0.409 0.0 HOH
 3.489
 OG
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 SER A:52 A:547 44.0 0.383 S -174.2 153.5 44.0 0.383 0.0 HOH
 4.070
 CB
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 SER C:51 C:547 47.0 0.409 -130.6 165.4 47.0 0.409 0.0 HOH
 9.749
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 SER A:51 A:547 41.0 0.357 -163.6 151.3 41.0 0.357 0.0 HOH
 3.735
 OG
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 SER A:51 A:547 46.0 0.4 -173.6 144.9 46.0 0.4 0.0 HOH
 3.392
 OG
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 SER A:74 A:74 49.0 0.426 S -174.0 151.1 49.0 0.426 0.0 HOH
 3.033
 OG
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 SER A:50 A:547 35.0 0.304 S -176.4 147.8 35.0 0.304 0.0 HOH
 4.110
 CA
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 SER A:50 A:547 37.0 0.322 S -168.5 152.8 37.0 0.322 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 SER A:50 A:547 40.0 0.348 B -179.0 155.9 40.0 0.348 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 SER A:49 AAA:1310 44.0 0.383 S -170.7 151.2 44.0 0.383 0.0 HOH
 2.652
 HG
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 SER A:48 A:547 46.0 0.4 S -175.5 155.3 46.0 0.4 0.0 HOH
 3.470
 OG
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 SER A:48 A:547 43.0 0.374 S 166.3 141.2 43.0 0.374 0.0 HOH
 5.860
 N
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 SER A:52 A:547 72.0 0.626 T -64.3 -22.6 72.0 0.626 0.0 HOH
 3.013
 OG
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 SER A:48 A:1310 27.0 0.235 -143.6 3.2 27.0 0.235 0.0 ACT
HOH
 9.981
3.034
 OG
OG
 O
O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 SER C:41 A:547 41.0 0.357 S -169.3 152.6 41.0 0.357 0.0 HOH
 3.391
 OG
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 SER C:41 A:547 41.0 0.357 S -178.8 150.1 41.0 0.357 0.0 HOH
 3.620
 CA
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 SER A:48 A:1310 43.0 0.374 S -168.8 155.6 43.0 0.374 0.0 HOH
 4.406
 CA
 O
SER B:48 B:1310 46.0 0.4 S -168.5 156.1 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 SER A:48 A:1310 41.0 0.357 -157.9 163.6 41.0 0.357 0.0 MES
HOH
 5.885
8.203
 OG
CB
 C2
O
SER C:48 C:1310 40.0 0.348 -158.2 154.8 NA NA NA
SER E:48 E:1310 37.0 0.322 -161.7 157.8 NA NA NA
SER G:48 G:1310 42.0 0.365 S -166.0 164.7 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 SER C:50 C:547 44.0 0.383 -165.0 152.4 44.0 0.383 0.0 HOH
 3.560
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 SER A:1310 A:1310 45.0 0.391 S -165.3 159.2
af-p04275-f2 1 P04275 99.93 0.0 SER A:1110 A:1110 43.0 0.374 S -169.7 162.9
af-p04275-f3 1 P04275 99.93 0.0 SER A:910 A:910 41.0 0.357 S -171.2 162.1
af-p04275-f6 1 P04275 100.0 0.0 SER A:310 A:310 42.0 0.365 S -172.1 165.3
af-p04275-f5 1 P04275 99.93 0.0 SER A:510 A:510 42.0 0.365 S -165.9 165.7
af-p04275-f7 1 P04275 100.0 0.0 SER A:110 A:110 28.0 0.243 S -164.0 165.6
af-p04275-f4 1 P04275 99.93 0.0 SER A:710 A:710 42.0 0.365 S -165.0 163.1