Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128659 . T A CCDS8539.1:NM_000552.3:c.3925Atc>Ttc_NP_000543.2:p.1309I>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ILE A:84 A:1309 18.0 0.103 B -85.5 123.0 18.0 0.103 0.0 HOH
 2.875
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ILE A:51 A:546 24.0 0.137 B -78.0 116.8 24.0 0.137 0.0 HOH
 4.682
 CG2
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ILE C:50 C:546 19.0 0.109 -67.4 87.8 19.0 0.109 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ILE A:50 A:546 26.0 0.149 B -70.4 110.4 26.0 0.149 0.0 HOH
 2.899
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ILE A:50 A:546 32.0 0.183 B -76.1 123.2 32.0 0.183 0.0 HOH
 4.729
 CG2
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ILE A:73 A:73 18.0 0.103 B -84.5 121.1 18.0 0.103 0.0 HOH
 2.549
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ILE A:49 A:546 11.0 0.063 B -74.8 121.1 11.0 0.063 0.0 HOH
 3.518
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ILE A:49 A:546 25.0 0.143 B -90.9 112.1 25.0 0.143 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ILE A:49 A:546 15.0 0.086 B -81.0 118.2 15.0 0.086 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ILE A:48 AAA:1309 26.0 0.149 B -84.1 115.7 26.0 0.149 0.0 HOH
 2.603
 HD11
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:47 A:546 19.0 0.123 B -73.2 118.9 19.0 0.123 0.0 HOH
 2.737
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:47 A:546 15.0 0.097 B -74.4 127.2 15.0 0.097 0.0 HOH
 3.444
 CG2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ILE A:51 A:546 16.0 0.091 T -70.6 -5.5 16.0 0.091 0.0 HOH
 2.599
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 VAL A:47 A:1309 10.0 0.065 -62.4 131.5 10.0 0.065 0.0 ACT
HOH
 8.205
3.186
 N
O
 O
O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ILE C:40 A:546 22.0 0.126 B -58.5 111.7 22.0 0.126 0.0 HOH
 3.239
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 VAL C:40 A:546 22.0 0.142 B -66.0 115.3 22.0 0.142 0.0 HOH
 2.820
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ILE A:47 A:1309 20.0 0.114 B -77.1 116.2 20.0 0.114 0.0 HOH
 2.959
 O
 O
ILE B:47 B:1309 22.0 0.126 B -78.9 115.7 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ILE A:47 A:1309 22.0 0.126 B -78.8 107.7 22.0 0.126 0.0 MES
HOH
 5.520
7.762
 O
N
 C6
O
ILE C:47 C:1309 22.0 0.126 B -72.4 104.1 NA NA NA
ILE E:47 E:1309 22.0 0.126 B -76.4 109.8 NA NA NA
ILE G:47 G:1309 26.0 0.149 B -70.3 108.3 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 ILE C:49 C:546 16.0 0.091 B -71.1 118.6 16.0 0.091 0.0 HOH
 2.880
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ILE A:1309 A:1309 17.0 0.097 B -65.0 109.9
af-p04275-f2 1 P04275 99.93 0.0 ILE A:1109 A:1109 11.0 0.063 B -66.7 120.6
af-p04275-f3 1 P04275 99.93 0.0 ILE A:909 A:909 16.0 0.091 B -66.2 120.2
af-p04275-f6 1 P04275 100.0 0.0 ILE A:309 A:309 10.0 0.057 B -68.4 123.4
af-p04275-f5 1 P04275 99.93 0.0 ILE A:509 A:509 15.0 0.086 B -68.9 117.9
af-p04275-f7 1 P04275 100.0 0.0 ILE A:109 A:109 13.0 0.074 B -71.8 118.8
af-p04275-f4 1 P04275 99.93 0.0 ILE A:709 A:709 14.0 0.08 B -67.2 117.9