Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128662 . G A CCDS8539.1:NM_000552.3:c.3922Cgc>Tgc_NP_000543.2:p.1308R>C Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 ARG A:83 A:1308 91.0 0.404 -85.6 92.3 91.0 0.404 0.0 HOH
 3.082
 NE
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 ARG A:50 A:545 106.0 0.471 -85.2 82.8 106.0 0.471 0.0 HOH
 3.145
 NE
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 ARG C:49 C:545 82.0 0.364 -82.2 77.1 82.0 0.364 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:49 A:545 99.0 0.44 -83.8 84.6 99.0 0.44 0.0 HOH
 3.710
 NH2
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 ARG A:49 A:545 75.0 0.333 -79.6 88.5 75.0 0.333 0.0 HOH
 6.252
 NH2
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 ARG A:72 A:72 84.0 0.373 -86.3 92.9 27.0 0.12 0.253 B:None:0.253
 HOH
 2.971
 NE
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 ARG A:48 A:545 92.0 0.409 -90.9 88.7 92.0 0.409 0.0 HOH
 4.190
 CG
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 ARG A:48 A:545 88.0 0.391 -78.6 92.6 88.0 0.391 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 ARG A:48 A:545 76.0 0.338 -51.0 98.5 76.0 0.338 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 ARG A:47 AAA:1308 85.0 0.378 -83.3 95.1 38.0 0.169 0.209 B:None:0.209
 HOH
 2.347
 HE
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:46 A:545 93.0 0.413 -86.7 88.6 93.0 0.413 0.0 HOH
 2.934
 NE
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 ARG A:46 A:545 85.0 0.378 -101.5 88.0 85.0 0.378 0.0 HOH
 6.386
 C
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 ARG A:50 A:545 80.0 0.356 T 59.8 70.6 80.0 0.356 0.0 HOH
 5.761
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 ARG A:46 A:1308 120.0 0.533 T 50.8 49.0 120.0 0.533 0.0 ACT
HOH
 2.354
2.837
 NE
O
 O
O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 ARG C:39 A:545 101.0 0.449 -87.8 74.6 101.0 0.449 0.0 HOH
 3.190
 NH2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 ARG C:39 A:545 98.0 0.436 -84.0 82.4 98.0 0.436 0.0 HOH
 2.748
 NE
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:46 A:1308 133.0 0.591 -92.1 90.2 133.0 0.591 0.0 HOH
 2.773
 NE
 O
ARG B:46 B:1308 94.0 0.418 -89.7 87.4 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:46 A:1308 60.0 0.267 -75.1 93.6 60.0 0.267 0.0 MES
HOH
 5.596
3.309
 NE
NE
 C6
O
ARG C:46 C:1308 90.0 0.4 -79.8 95.1 NA NA NA
ARG E:46 E:1308 109.0 0.484 -77.7 94.7 NA NA NA
ARG G:46 G:1308 102.0 0.453 -76.2 83.8 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 HIS C:48 C:545 69.0 0.354 -88.5 81.8 69.0 0.354 0.0 HOH
 3.810
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 ARG A:1308 A:1308 107.0 0.476 -77.4 70.4
af-p04275-f2 1 P04275 99.93 0.0 ARG A:1108 A:1108 76.0 0.338 -77.1 73.0
af-p04275-f3 1 P04275 99.93 0.0 ARG A:908 A:908 99.0 0.44 -77.6 72.5
af-p04275-f6 1 P04275 100.0 0.0 ARG A:308 A:308 98.0 0.436 -76.9 74.2
af-p04275-f5 1 P04275 99.93 0.0 ARG A:508 A:508 93.0 0.413 -77.0 76.6
af-p04275-f7 1 P04275 100.0 0.0 ARG A:108 A:108 82.0 0.364 -74.3 79.6
af-p04275-f4 1 P04275 99.93 0.0 ARG A:708 A:708 105.0 0.467 -76.8 74.4