Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128664 . A C CCDS8539.1:NM_000552.3:c.3920cTg>cGg_NP_000543.2:p.1307L>R Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 LEU A:82 A:1307 4.0 0.024 B -121.9 144.8 4.0 0.024 0.0 HOH
 2.763
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 LEU A:49 A:544 18.0 0.106 B -112.5 139.6 18.0 0.106 0.0 HOH
 8.100
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 LEU C:48 C:544 9.0 0.053 B -132.2 139.4 9.0 0.053 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:48 A:544 6.0 0.035 B -123.3 140.1 6.0 0.035 0.0 HOH
 3.104
 O
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:48 A:544 10.0 0.059 B -132.2 138.2 10.0 0.059 0.0 HOH
 4.441
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 LEU A:71 A:71 7.0 0.041 B -114.6 146.3 7.0 0.041 0.0 HOH
 2.571
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 LEU A:47 A:544 4.0 0.024 B -130.8 140.5 4.0 0.024 0.0 HOH
 3.435
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 LEU A:47 A:544 4.0 0.024 B -135.2 138.1 4.0 0.024 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 LEU A:47 A:544 10.0 0.059 S -157.0 126.9 10.0 0.059 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 LEU A:46 AAA:1307 9.0 0.053 B -121.9 147.1 9.0 0.053 0.0 HOH
 3.983
 O
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:45 A:544 3.0 0.018 B -131.3 144.3 3.0 0.018 0.0 HOH
 2.718
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:45 A:544 4.0 0.024 B -126.1 157.8 4.0 0.024 0.0 HOH
 4.769
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 LEU A:49 A:544 4.0 0.024 T -85.0 -7.6 4.0 0.024 0.0 HOH
 7.660
 N
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 LEU A:45 A:1307 2.0 0.012 T -87.2 5.1 2.0 0.012 0.0 ACT
HOH
 6.544
2.787
 C
O
 CH3
O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 LEU C:38 A:544 6.0 0.035 B -126.2 148.0 6.0 0.035 0.0 HOH
 3.498
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 LEU C:38 A:544 5.0 0.029 B -128.8 146.3 5.0 0.029 0.0 HOH
 2.642
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:45 A:1307 17.0 0.1 S -119.7 151.5 17.0 0.1 0.0 HOH
 2.736
 O
 O
LEU B:45 B:1307 7.0 0.041 S -115.8 150.6 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:45 A:1307 1.0 0.006 S -109.5 138.0 1.0 0.006 0.0 MES
HOH
 7.997
8.122
 O
C
 O1S
O
LEU C:45 C:1307 7.0 0.041 S -84.2 148.3 NA NA NA
LEU E:45 E:1307 11.0 0.065 S -119.3 141.3 NA NA NA
LEU G:45 G:1307 14.0 0.082 S -108.3 145.6 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 LEU C:47 C:544 0.0 0.0 B -115.4 138.8 0.0 0.0 0.0 HOH
 2.653
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 LEU A:1307 A:1307 20.0 0.118 B -104.6 141.1
af-p04275-f2 1 P04275 99.93 0.0 LEU A:1107 A:1107 0.0 0.0 B -107.2 141.0
af-p04275-f3 1 P04275 99.93 0.0 LEU A:907 A:907 1.0 0.006 B -110.5 140.8
af-p04275-f6 1 P04275 100.0 0.0 LEU A:307 A:307 0.0 0.0 B -103.0 140.6
af-p04275-f5 1 P04275 99.93 0.0 LEU A:507 A:507 1.0 0.006 B -104.9 141.1
af-p04275-f7 1 P04275 100.0 0.0 LEU A:107 A:107 1.0 0.006 B -105.8 135.7
af-p04275-f4 1 P04275 99.93 0.0 LEU A:707 A:707 0.0 0.0 B -105.6 140.6