Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128716 . C A CCDS8539.1:NM_000552.3:c.3868Gag>Tag_NP_000543.2:p.1290E>* Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 GLU A:65 A:1290 124.0 0.653 H -56.4 -41.2 124.0 0.653 0.0 EDO
HOH
 6.673
2.560
 C
OE2
 C1
O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 GLU A:32 A:527 117.0 0.616 H -51.9 -43.8 117.0 0.616 0.0 HOH
 6.229
 N
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 GLU C:31 C:527 122.0 0.642 H -61.4 -47.1 122.0 0.642 0.0 HOH
 2.787
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLU A:31 A:527 118.0 0.621 H -57.4 -46.6 118.0 0.621 0.0 HOH
 5.201
 OE2
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 GLU A:31 A:527 117.0 0.616 H -65.1 -52.3 117.0 0.616 0.0 HOH
 2.666
 O
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 GLU A:54 A:54 122.0 0.642 H -58.7 -38.5 122.0 0.642 0.0 HOH
 2.758
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 GLU A:30 A:527 114.0 0.6 H -52.2 -43.6 114.0 0.6 0.0 HOH
 3.006
 N
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 GLU A:30 A:527 131.0 0.689 H -55.6 -35.7 131.0 0.689 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 GLU A:30 A:527 123.0 0.647 H -60.5 -46.5 123.0 0.647 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 GLU A:29 AAA:1290 115.0 0.605 H -46.0 -44.6 115.0 0.605 0.0 HOH
 2.374
 OE2
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLU A:28 A:527 124.0 0.653 H -58.8 -39.4 124.0 0.653 0.0 HOH
 2.800
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 GLU A:28 A:527 135.0 0.711 T -69.2 -32.9 135.0 0.711 0.0 HOH
 2.509
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 GLU A:32 A:527 121.0 0.637 H -55.8 -44.2 121.0 0.637 0.0 HOH
 3.090
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 GLU A:28 A:1290 122.0 0.642 H -64.3 -39.6 122.0 0.642 0.0 HOH
 2.776
 OE1
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 GLU C:21 A:527 138.0 0.726 H -59.7 -41.1 138.0 0.726 0.0 HOH
 2.616
 OE1
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 GLU C:21 A:527 135.0 0.711 H -55.0 -43.2 135.0 0.711 0.0 HOH
 2.622
 OE2
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLU A:28 A:1290 119.0 0.626 H -62.0 -42.6 119.0 0.626 0.0 PEG
CA
HOH
 2.105
9.440
2.892
 OE2
N
OE1
 O1
CA
O
GLU B:28 B:1290 121.0 0.637 H -61.9 -42.2 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 GLU A:28 A:1290 125.0 0.658 H -63.1 -27.8 125.0 0.658 0.0
GLU C:28 C:1290 134.0 0.705 H -65.7 -28.8 NA NA NA
GLU E:28 E:1290 136.0 0.716 T -66.8 -22.6 NA NA NA
GLU G:28 G:1290 124.0 0.653 H -62.6 -30.1 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 GLU C:30 C:527 126.0 0.663 H -37.9 -42.4 126.0 0.663 0.0 HOH
 7.456
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 GLU A:1290 A:1290 128.0 0.674 H -52.3 -37.8
af-p04275-f2 1 P04275 99.93 0.0 GLU A:1090 A:1090 107.0 0.563 H -57.9 -36.7
af-p04275-f3 1 P04275 99.93 0.0 GLU A:890 A:890 128.0 0.674 H -54.0 -40.2
af-p04275-f6 1 P04275 100.0 0.0 GLU A:290 A:290 130.0 0.684 H -55.1 -40.3
af-p04275-f5 1 P04275 99.93 0.0 GLU A:490 A:490 130.0 0.684 H -56.3 -38.6
af-p04275-f7 1 P04275 100.0 0.0 GLU A:90 A:90 129.0 0.679 H -56.7 -39.6
af-p04275-f4 1 P04275 99.93 0.0 GLU A:690 A:690 131.0 0.689 H -55.5 -38.7