Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128721 . A C CCDS8539.1:NM_000552.3:c.3863cTg>cGg_NP_000543.2:p.1288L>R Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 LEU A:63 A:1288 5.0 0.029 S -95.3 130.2 5.0 0.029 0.0 EDO
HOH
 8.004
3.774
 CD2
CB
 C2
O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 LEU A:30 A:525 2.0 0.012 S -101.1 127.4 2.0 0.012 0.0 HOH
 3.729
 CD2
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 LEU C:29 C:525 4.0 0.024 S -120.5 132.4 4.0 0.024 0.0 HOH
 4.205
 CD1
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:29 A:525 7.0 0.041 S -93.8 128.0 7.0 0.041 0.0 HOH
 3.642
 CB
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 LEU A:29 A:525 9.0 0.053 S -114.0 151.6 9.0 0.053 0.0 HOH
 3.281
 CB
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 LEU A:52 A:52 6.0 0.035 S -104.4 126.2 6.0 0.035 0.0 HOH
 3.706
 CB
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 LEU A:28 A:525 4.0 0.024 S -110.6 134.1 4.0 0.024 0.0 HOH
 3.802
 CB
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 LEU A:28 A:525 7.0 0.041 S -126.1 132.1 7.0 0.041 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 LEU A:28 A:525 7.0 0.041 S -142.2 119.3 7.0 0.041 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 LEU A:27 AAA:1288 7.0 0.041 S -103.0 131.0 7.0 0.041 0.0 HOH
 3.894
 HA
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:26 A:525 6.0 0.035 S -108.2 134.7 6.0 0.035 0.0 HOH
 3.728
 CB
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 LEU A:26 A:525 6.0 0.035 S -114.5 128.9 6.0 0.035 0.0 HOH
 3.694
 CD2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 LEU A:30 A:525 5.0 0.029 S -123.2 133.7 5.0 0.029 0.0 HOH
 3.999
 CB
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 LEU A:26 A:1288 6.0 0.035 S -105.9 130.5 6.0 0.035 0.0 HOH
 3.823
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 LEU C:19 A:525 4.0 0.024 S -114.2 122.4 4.0 0.024 0.0 HOH
 3.470
 CB
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 LEU C:19 A:525 4.0 0.024 S -112.8 132.6 4.0 0.024 0.0 HOH
 3.787
 CB
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:26 A:1288 6.0 0.035 S -103.6 129.0 6.0 0.035 0.0 CA
HOH
 6.481
3.639
 CA
CD2
 CA
O
LEU B:26 B:1288 6.0 0.035 S -104.7 130.0 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 LEU A:26 A:1288 10.0 0.059 S -106.0 125.7 10.0 0.059 0.0
LEU C:26 C:1288 4.0 0.024 S -105.2 126.7 NA NA NA
LEU E:26 E:1288 8.0 0.047 S -105.8 126.2 NA NA NA
LEU G:26 G:1288 6.0 0.035 S -108.4 125.6 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 LEU C:28 C:525 5.0 0.029 S -134.3 127.6 5.0 0.029 0.0 HOH
 4.206
 CD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 LEU A:1288 A:1288 25.0 0.147 S -90.6 144.4
af-p04275-f2 1 P04275 99.93 0.0 LEU A:1088 A:1088 5.0 0.029 S -92.7 135.7
af-p04275-f3 1 P04275 99.93 0.0 LEU A:888 A:888 4.0 0.024 S -97.3 131.6
af-p04275-f6 1 P04275 100.0 0.0 LEU A:288 A:288 3.0 0.018 S -102.1 135.5
af-p04275-f5 1 P04275 99.93 0.0 LEU A:488 A:488 5.0 0.029 S -102.4 135.5
af-p04275-f7 1 P04275 100.0 0.0 LEU A:88 A:88 6.0 0.035 S -97.0 146.6
af-p04275-f4 1 P04275 99.93 0.0 LEU A:688 A:688 5.0 0.029 S -101.7 133.6