Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128730 . G A CCDS8539.1:NM_000552.3:c.3854tCc>tTc_NP_000543.2:p.1285S>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 SER A:60 A:1285 3.0 0.026 B -82.9 169.6 3.0 0.026 0.0 HOH
 2.781
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 SER A:27 A:522 2.0 0.017 B -79.7 169.1 2.0 0.017 0.0 HOH
 2.786
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 SER C:26 C:522 1.0 0.009 B -77.6 165.6 1.0 0.009 0.0 HOH
 3.351
 O
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 SER A:26 A:522 3.0 0.026 B -66.2 173.5 3.0 0.026 0.0 DG
HOH
 8.124
2.669
 CB
O
 O6
O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 SER A:26 A:522 5.0 0.043 B -68.6 166.1 5.0 0.043 0.0 DG
HOH
 8.332
2.560
 CB
O
 O6
O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 SER A:49 A:49 0.0 0.0 B -75.5 171.4 0.0 0.0 0.0 HOH
 2.817
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 SER A:25 A:522 3.0 0.026 B -75.2 175.1 3.0 0.026 0.0 HOH
 2.708
 O
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 SER A:25 A:522 1.0 0.009 B -100.3 159.5 1.0 0.009 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 SER A:25 A:522 1.0 0.009 B -102.1 171.7 1.0 0.009 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 SER A:24 AAA:1285 2.0 0.017 B -77.6 161.1 2.0 0.017 0.0 HOH
 2.559
 HB2
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 SER A:23 A:522 3.0 0.026 B -77.0 167.6 3.0 0.026 0.0 HOH
 2.845
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 SER A:23 A:522 1.0 0.009 B -76.1 161.1 1.0 0.009 0.0 HOH
 2.724
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 SER A:27 A:522 2.0 0.017 B -91.2 164.8 2.0 0.017 0.0 HOH
 3.186
 O
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 SER A:23 A:1285 1.0 0.009 B -87.0 177.3 1.0 0.009 0.0 HOH
 2.840
 O
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 SER C:16 A:522 1.0 0.009 B -108.1 159.1 1.0 0.009 0.0 HOH
 2.980
 O
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 SER C:16 A:522 1.0 0.009 B -76.1 170.2 1.0 0.009 0.0 HOH
 2.922
 O
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 SER A:23 A:1285 1.0 0.009 B -89.3 173.6 1.0 0.009 0.0 CA
HOH
 9.829
2.746
 O
O
 CA
O
SER B:23 B:1285 2.0 0.017 B -89.9 174.7 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 SER A:23 A:1285 3.0 0.026 B -88.4 178.6 3.0 0.026 0.0 HOH
 8.756
 OG
 O
SER C:23 C:1285 2.0 0.017 B -94.5 178.6 NA NA NA
SER E:23 E:1285 3.0 0.026 B -90.2 175.8 NA NA NA
SER G:23 G:1285 0.0 0.0 B -103.1 -179.9 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 SER C:25 C:522 1.0 0.009 B -89.4 -167.2 1.0 0.009 0.0 HOH
 9.990
 OG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 SER A:1285 A:1285 0.0 0.0 B -76.0 158.3
af-p04275-f2 1 P04275 99.93 0.0 SER A:1085 A:1085 0.0 0.0 B -73.2 162.0
af-p04275-f3 1 P04275 99.93 0.0 SER A:885 A:885 0.0 0.0 B -75.5 163.2
af-p04275-f6 1 P04275 100.0 0.0 SER A:285 A:285 0.0 0.0 B -81.4 161.0
af-p04275-f5 1 P04275 99.93 0.0 SER A:485 A:485 0.0 0.0 B -80.3 158.1
af-p04275-f7 1 P04275 100.0 0.0 SER A:85 A:85 0.0 0.0 B -83.4 160.8
af-p04275-f4 1 P04275 99.93 0.0 SER A:685 A:685 0.0 0.0 B -76.9 160.3