Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128749 . C A CCDS8539.1:NM_000552.3:c.3835Gtc>Ttc_NP_000543.2:p.1279V>F Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 VAL A:54 A:1279 0.0 0.0 E -112.1 121.4 0.0 0.0 0.0 HOH
 5.785
 CG1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 VAL A:21 A:516 0.0 0.0 E -109.1 121.8 0.0 0.0 0.0 HOH
 5.877
 CG1
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 VAL C:20 C:516 0.0 0.0 E -117.4 118.6 0.0 0.0 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 VAL A:20 A:516 0.0 0.0 E -117.2 114.1 0.0 0.0 0.0 HOH
 7.811
 CG1
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 VAL A:20 A:516 0.0 0.0 E -114.1 125.7 0.0 0.0 0.0 HOH
 8.759
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 VAL A:43 A:43 0.0 0.0 E -109.5 124.1 0.0 0.0 0.0 HOH
 5.836
 CG1
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 VAL A:19 A:516 0.0 0.0 E -108.1 121.4 0.0 0.0 0.0 HOH
 6.264
 CG2
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 VAL A:19 A:516 0.0 0.0 E -104.9 119.2 0.0 0.0 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 VAL A:19 A:516 0.0 0.0 E -106.9 131.7 0.0 0.0 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 VAL A:18 AAA:1279 0.0 0.0 E -113.9 117.5 0.0 0.0 0.0 HOH
 7.995
 HG22
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:17 A:516 0.0 0.0 E -111.2 124.8 0.0 0.0 0.0 HOH
 5.416
 CG1
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 VAL A:17 A:516 0.0 0.0 E -112.6 109.7 0.0 0.0 0.0 HOH
 6.540
 CG2
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 VAL A:21 A:516 0.0 0.0 E -114.5 120.3 0.0 0.0 0.0 HOH
 7.936
 CG1
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 VAL A:17 A:1279 0.0 0.0 E -108.9 118.8 0.0 0.0 0.0 HOH
 5.833
 CG1
 O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 VAL C:10 A:516 0.0 0.0 E -107.9 111.4 0.0 0.0 0.0 HOH
 5.952
 CG2
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 VAL C:10 A:516 0.0 0.0 E -108.3 116.9 0.0 0.0 0.0 HOH
 5.620
 CG1
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 VAL A:17 A:1279 0.0 0.0 E -112.9 118.7 0.0 0.0 0.0 HOH
 6.027
 CG2
 O
VAL B:17 B:1279 0.0 0.0 E -112.5 119.7 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 VAL A:17 A:1279 0.0 0.0 E -125.5 122.2 0.0 0.0 0.0
VAL C:17 C:1279 0.0 0.0 E -123.6 119.1 NA NA NA
VAL E:17 E:1279 0.0 0.0 E -129.0 120.7 NA NA NA
VAL G:17 G:1279 0.0 0.0 E -120.9 120.4 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 VAL C:19 C:516 0.0 0.0 E -113.0 117.9 0.0 0.0 0.0 HOH
 6.163
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 VAL A:1279 A:1279 0.0 0.0 E -117.9 119.5
af-p04275-f2 1 P04275 99.93 0.0 VAL A:1079 A:1079 0.0 0.0 E -107.7 119.3
af-p04275-f3 1 P04275 99.93 0.0 VAL A:879 A:879 0.0 0.0 E -117.0 122.2
af-p04275-f6 1 P04275 100.0 0.0 VAL A:279 A:279 0.0 0.0 E -107.5 115.7
af-p04275-f5 1 P04275 99.93 0.0 VAL A:479 A:479 0.0 0.0 E -112.8 119.4
af-p04275-f7 1 P04275 100.0 0.0 VAL A:79 A:79 0.0 0.0 E -114.7 116.9
af-p04275-f4 1 P04275 99.93 0.0 VAL A:679 A:679 0.0 0.0 E -115.4 122.4