Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128770 . A C CCDS8539.1:NM_000552.3:c.3814Tgc>Ggc_NP_000543.2:p.1272C>G Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 CYS A:47 A:1272 4.0 0.03 B -79.1 116.4 4.0 0.03 0.0 HOH
 3.759
 CA
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 CYS A:14 A:509 2.0 0.015 B -104.4 113.4 2.0 0.015 0.0 HOH
 8.824
 O
 O
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 CYS C:13 C:509 11.0 0.081 B -59.9 117.2 11.0 0.081 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 CYS A:13 A:509 1.0 0.007 B -89.7 112.7 1.0 0.007 0.0 HOH
 3.604
 CA
 O
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 CYS A:13 A:509 3.0 0.022 B -55.9 103.7 3.0 0.022 0.0 HOH
 5.279
 N
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 CYS A:36 A:36 2.0 0.015 B -80.8 107.3 0.0 0.0 0.015 B:None:0.015
 HOH
 3.961
 C
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 CYS A:12 A:509 1.0 0.007 B -98.1 118.5 1.0 0.007 0.0 HOH
 3.868
 CA
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 CYS A:12 A:509 5.0 0.037 B -46.4 111.9 5.0 0.037 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 CYS A:12 A:509 20.0 0.148 -111.7 175.6 20.0 0.148 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 CYS A:11 AAA:1272 2.0 0.015 B -79.7 107.7 0.0 0.0 0.015 B:None:0.015
 HOH
 3.292
 HA
 O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 CYS A:10 A:509 6.0 0.044 B -77.7 111.9 6.0 0.044 0.0 HOH
 3.661
 C
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 CYS A:10 A:509 4.0 0.03 B -56.2 101.6 4.0 0.03 0.0 HOH
 5.734
 N
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 CYS A:14 A:509 10.0 0.074 -179.3 146.7 10.0 0.074 0.0 HOH
 5.194
 CB
 O
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 CYS A:10 A:1272 12.0 0.089 -155.2 138.5 12.0 0.089 0.0 ACT
HOH
 3.710
2.841
 CA
O
 CH3
O
1oak 3 P04275 99.49 1e-128 X-RAY
 1998-10-21 CYS C:3 A:509 0.0 0.0 B -112.2 111.4 0.0 0.0 0.0 HOH
 3.639
 CA
 O
1fns 3 P04275 98.97 2e-128 X-RAY
 2000-10-18 CYS C:3 A:509 0.0 0.0 B -101.4 112.3 0.0 0.0 0.0 HOH
 3.729
 CA
 O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:10 A:1272 169.0 0.751 T -58.6 128.4 169.0 0.751 0.0 HOH
 3.256
 CA
 O
ARG B:10 B:1272 114.0 0.507 T -62.9 -51.6 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 ARG A:10 A:1272 145.0 0.644 S -88.3 -43.0 145.0 0.644 0.0 MES
HOH
 8.248
3.162
 NH2
NE
 C6
O
ARG C:10 C:1272 124.0 0.551 S -90.2 -64.0 NA NA NA
ARG E:10 E:1272 135.0 0.6 S -93.0 -52.0 NA NA NA
ARG G:10 G:1272 145.0 0.644 -127.0 -59.8 NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 CYS C:12 C:509 1.0 0.007 B -109.7 124.4 1.0 0.007 0.0 HOH
 7.014
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 CYS A:1272 A:1272 54.0 0.4 B -71.2 116.8
af-p04275-f2 1 P04275 99.93 0.0 CYS A:1072 A:1072 0.0 0.0 B -128.9 118.5
af-p04275-f3 1 P04275 99.93 0.0 CYS A:872 A:872 0.0 0.0 B -126.9 115.9
af-p04275-f6 1 P04275 100.0 0.0 CYS A:272 A:272 1.0 0.007 B -136.2 119.6
af-p04275-f5 1 P04275 99.93 0.0 CYS A:472 A:472 1.0 0.007 B -129.1 115.0
af-p04275-f7 1 P04275 100.0 0.0 CYS A:72 A:72 1.0 0.007 B -132.2 115.2
af-p04275-f4 1 P04275 99.93 0.0 CYS A:672 A:672 1.0 0.007 B -130.0 116.2