Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128782 . G A CCDS8539.1:NM_000552.3:c.3802Cac>Tac_NP_000543.2:p.1268H>Y Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 HIS A:43 A:1268 57.0 0.292 S -128.2 164.2 57.0 0.292 0.0 HOH
 2.639
 ND1
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 HIS A:10 A:505 175.0 0.897 360.0 -147.4 175.0 0.897 0.0
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 HIS C:9 C:505 73.0 0.374 S -105.8 170.9 73.0 0.374 0.0 HOH
 9.096
 NE2
 O
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 HIS A:9 NA:NA DO NA DO DO DO NA NA NA
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 HIS A:9 A:505 169.0 0.867 S -101.2 -53.2 169.0 0.867 0.0 HOH
 3.034
 CB
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 HIS A:32 A:32 58.0 0.297 S -140.7 161.7 49.0 0.251 0.046 B:None:0.046
 HOH
 2.816
 ND1
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 HIS A:8 A:505 57.0 0.292 -130.1 176.2 57.0 0.292 0.0 HOH
 3.262
 CB
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 HIS A:8 A:505 66.0 0.338 S -122.7 163.4 66.0 0.338 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 HIS A:8 A:505 194.0 0.995 360.0 -23.0 194.0 0.995 0.0
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 HIS A:7 AAA:1268 61.0 0.313 S -136.8 164.9 52.0 0.267 0.046 B:None:0.046
 SO4
HOH
 2.657
2.255
 HD1
H
 O4
O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 HIS A:6 A:505 58.0 0.297 S -133.9 165.0 58.0 0.297 0.0 HOH
 2.689
 N
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 HIS A:6 A:505 68.0 0.349 S -130.4 175.9 68.0 0.349 0.0 HOH
 3.066
 O
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 HIS A:10 NA:NA DO NA DO DO DO NA NA NA
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 HIS A:6 A:1268 14.0 0.072 -75.2 168.5 14.0 0.072 0.0 CAC
ACT
CA
HOH
 3.032
9.302
4.827
3.183
 ND1
O
CE1
CD2
 O2
OXT
CA
O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 HIS A:6 A:1268 115.0 0.59 -126.1 147.1 115.0 0.59 0.0 HOH
 3.041
 CD2
 O
HIS B:6 B:1268 39.0 0.2 -66.4 135.9 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 HIS A:6 A:1268 40.0 0.205 -64.3 150.7 40.0 0.205 0.0 HOH
 7.462
 O
 O
HIS C:6 C:1268 106.0 0.544 360.0 -163.4 NA NA NA
HIS E:6 E:1268 66.0 0.338 -69.7 130.4 NA NA NA
HIS G:6 NA:NA DO NA DO DO DO NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 HIS C:8 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 HIS A:1268 A:1268 78.0 0.4 -148.3 147.6
af-p04275-f2 1 P04275 99.93 0.0 HIS A:1068 A:1068 159.0 0.815 -99.4 148.0
af-p04275-f3 1 P04275 99.93 0.0 HIS A:868 A:868 140.0 0.718 S -140.6 153.7
af-p04275-f6 1 P04275 100.0 0.0 HIS A:268 A:268 154.0 0.79 S -149.8 160.1
af-p04275-f5 1 P04275 99.93 0.0 HIS A:468 A:468 171.0 0.877 -71.0 141.3
af-p04275-f7 1 P04275 100.0 0.0 HIS A:68 A:68 155.0 0.795 S -139.7 161.4
af-p04275-f4 1 P04275 99.93 0.0 HIS A:668 A:668 154.0 0.79 75.7 111.9