Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6128787 . G A CCDS8539.1:NM_000552.3:c.3797cCg>cTg_NP_000543.2:p.1266P>L Homo sapiens von Willebrand factor (VWF), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5bv8 1 P04275 99.11 3e-149 X-RAY
 2015-12-23 PRO A:41 A:1266 70.0 0.483 -62.0 143.4 70.0 0.483 0.0 HOH
 2.752
 O
 O
7f49 1 P04275 99.05 2e-140 X-RAY
 2021-07-07 PRO A:8 NA:NA DO NA DO DO DO NA NA NA
1uex 3 P04275 99.52 3e-140 X-RAY
 2003-09-30 PRO C:7 C:503 68.0 0.469 -67.2 112.1 68.0 0.469 0.0
3hxo 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 PRO A:7 NA:NA DO NA DO DO DO NA NA NA
3hxq 1 P04275 99.52 3e-140 X-RAY
 2009-11-17 PRO A:7 A:503 104.0 0.717 -77.4 135.2 104.0 0.717 0.0 HOH
 3.679
 O
 O
7eow 1 P04275 100.0 7e-140 X-RAY
 2021-07-07 PRO A:30 A:30 72.0 0.497 -69.3 143.8 14.0 0.097 0.4 B:None:0.4
 HOH
 2.736
 O
 O
1auq 1 P04275 99.52 1e-139 X-RAY
 1998-10-14 PRO A:6 A:503 68.0 0.469 -78.9 143.3 68.0 0.469 0.0 HOH
 3.792
 C
 O
1u0n 1 P04275 99.52 1e-139 X-RAY
 2005-04-19 PRO A:6 A:503 69.0 0.476 -71.6 136.3 69.0 0.476 0.0
1m10 1 P04275 99.04 7e-139 X-RAY
 2002-08-28 PRO A:6 NA:NA DO NA DO DO DO NA NA NA
7a6o 1 L8E853 99.51 5e-137 X-RAY
 2021-03-03 PRO A:5 AAA:1266 73.0 0.503 -61.9 139.8 14.0 0.097 0.406 B:None:0.407
 SO4
HOH
 7.380
2.301
 HB2
HD2
 O1
O
1ijb 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 PRO A:4 A:503 69.0 0.476 -66.3 148.5 69.0 0.476 0.0 HOH
 2.740
 O
 O
1ijk 1 P04275 99.01 4e-134 X-RAY
 2002-07-10 PRO A:4 A:503 75.0 0.517 -35.7 114.3 75.0 0.517 0.0 HOH
 3.575
 CB
 O
1sq0 1 P04275 99.01 5e-134 X-RAY
 2004-04-13 PRO A:8 NA:NA DO NA DO DO DO NA NA NA
4c2a 1 P04275 98.48 3e-130 X-RAY
 2014-01-08 PRO A:4 A:1266 126.0 0.869 360.0 163.3 126.0 0.869 0.0 CAC
CA
HOH
 4.311
4.664
2.716
 CB
CG
O
 O1
CA
O
4c29 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 PRO A:4 A:1266 177.0 1.0 360.0 127.9 177.0 1.0 0.0 HOH
 2.584
 O
 O
PRO B:4 B:1266 158.0 1.0 360.0 128.1 NA NA NA
4c2b 1 P04275 98.48 4e-128 X-RAY
 2014-01-08 PRO A:4 NA:NA DO NA DO DO DO NA NA NA
PRO C:4 NA:NA DO NA DO DO DO NA NA NA
PRO E:4 NA:NA DO NA DO DO DO NA NA NA
PRO G:4 NA:NA DO NA DO DO DO NA NA NA
1u0o 3 Q8CIZ8 87.02 2e-119 X-RAY
 2005-04-19 PRO C:6 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04275-f1 1 P04275 99.93 0.0 PRO A:1266 A:1266 110.0 0.759 -65.9 121.4
af-p04275-f2 1 P04275 99.93 0.0 PRO A:1066 A:1066 107.0 0.738 -75.6 151.6
af-p04275-f3 1 P04275 99.93 0.0 PRO A:866 A:866 92.0 0.634 -60.0 107.4
af-p04275-f6 1 P04275 100.0 0.0 PRO A:266 A:266 85.0 0.586 -59.1 123.0
af-p04275-f5 1 P04275 99.93 0.0 PRO A:466 A:466 121.0 0.834 -69.3 139.4
af-p04275-f7 1 P04275 100.0 0.0 PRO A:66 A:66 78.0 0.538 -64.5 108.6
af-p04275-f4 1 P04275 99.93 0.0 PRO A:666 A:666 127.0 0.876 -83.9 125.5