Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6923329 . G A CCDS8562.1:NM_000616.4:c.236cGc>cAc_NP_000607.1:p.79R>H Homo sapiens CD4 molecule (CD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7t0o 4 P01730 100.0 0.0 EM
 2022-01-12 ARG G:54 H:54 41.0 0.182 T -76.7 -43.3 40.0 0.178 0.004 H:None:0.004
ARG I:54 L:54 79.0 0.351 T -75.6 -50.9 72.0 0.32 0.031 J:None:0.031
ARG K:54 M:54 79.0 0.351 T -75.8 -50.8 71.0 0.316 0.035 L:None:0.036
7t0r 3 P01730 99.73 0.0 X-RAY
 2022-01-12 ARG C:54 A:54 40.0 0.178 T -88.3 -33.7 37.0 0.164 0.014 G:None:0.013
ARG F:54 D:54 85.0 0.378 T -87.9 -40.0 NA NA NA
1wio 1 P01730 100.0 0.0 X-RAY
 1997-07-07 ARG A:54 A:54 19.0 0.084 G -134.0 0.2 19.0 0.084 0.0
ARG B:54 B:54 19.0 0.084 G -136.1 1.6 NA NA NA
1wip 1 P01730 100.0 0.0 X-RAY
 1997-07-07 ARG A:54 A:54 19.0 0.084 G -133.9 0.1 19.0 0.084 0.0
ARG B:54 B:54 19.0 0.084 G -136.2 1.7 NA NA NA
1wiq 1 P01730 100.0 0.0 X-RAY
 1997-07-07 ARG A:54 A:54 21.0 0.093 G -134.0 0.3 21.0 0.093 0.0
ARG B:54 B:54 19.0 0.084 G -136.1 1.7 NA NA NA
5u1f 5 P01730 100.0 0.0 EM
 2017-02-22 ARG I:54 M:1054 39.0 NA G -119.5 -0.1 39.0 NA NA
6met 2 P01730 100.0 0.0 EM
 2018-12-12 ARG B:54 A:54 62.0 0.276 T -123.5 -34.3 62.0 0.276 0.0
3t0e 5 P01730 99.45 0.0 X-RAY
 2012-03-07 ARG E:54 E:54 48.0 0.213 G -61.9 -16.6 48.0 0.213 0.0
4q6i 3 P01730 100.0 1e-148 X-RAY
 2014-07-23 ARG C:79 C:54 36.0 0.16 T -90.8 4.1 NA NA NA
ARG I:79 I:54 34.0 0.151 T -90.4 4.9 NA NA NA
ARG J:79 J:54 32.0 0.142 T -90.9 3.4 NA NA NA
ARG K:79 K:54 35.0 0.156 T -90.3 4.9 35.0 0.156 0.0
1g9m 2 P01730 99.46 6e-129 X-RAY
 2000-12-27 ARG B:54 C:54 21.0 0.093 G -120.5 -0.1 21.0 0.093 0.0 HOH
 2.618
 NE
 O
1g9n 2 P01730 99.46 6e-129 X-RAY
 2000-12-27 ARG B:54 C:54 20.0 0.089 G -124.1 3.2 20.0 0.089 0.0 HOH
 5.845
 NH2
 O
1gc1 2 P01730 99.46 6e-129 X-RAY
 1998-07-08 ARG B:54 C:54 13.0 0.058 T -103.1 -19.6 13.0 0.058 0.0 HOH
 2.624
 NH2
 O
1rzj 2 P01730 99.46 6e-129 X-RAY
 2004-02-03 ARG B:54 C:54 22.0 0.098 G -105.3 3.9 22.0 0.098 0.0 HOH
 2.806
 NE
 O
1rzk 2 P01730 99.46 6e-129 X-RAY
 2004-02-03 ARG B:54 C:54 20.0 0.089 G -128.5 -5.4 20.0 0.089 0.0 HOH
 5.962
 NH2
 O
3j70 3 P01730 99.46 6e-129 EM
 2015-08-26 ARG C:54 C:54 23.0 0.102 T -106.5 -7.3 23.0 0.102 0.0
ARG H:54 O:54 23.0 0.102 T -106.5 -7.3 23.0 0.102 0.0
ARG M:54 T:54 23.0 0.102 T -106.5 -7.4 23.0 0.102 0.0
4h8w 4 P01730 99.46 6e-129 X-RAY
 2014-04-09 ARG D:54 C:54 17.0 0.076 G -112.0 5.2 17.0 0.076 0.0 HOH
 3.039
 O
 O
4jm2 6 P01730 99.46 6e-129 X-RAY
 2013-05-29 ARG F:54 F:54 38.0 0.169 G -117.7 6.6 38.0 0.169 0.0
4rqs 1 P01730 99.46 6e-129 X-RAY
 2014-12-31 ARG A:54 B:54 20.0 0.089 T -95.4 1.4 20.0 0.089 0.0
5a8h 2 P01730 99.46 6e-129 EM
 2015-08-05 ARG B:54 B:54 19.0 0.084 G -128.5 -5.5 19.0 0.084 0.0
ARG H:54 H:54 19.0 0.084 G -128.6 -5.4 19.0 0.084 0.0
ARG N:54 N:54 20.0 0.089 G -128.5 -5.4 20.0 0.089 0.0
5vn3 4 P01730 99.46 6e-129 EM
 2017-07-12 ARG D:54 C:54 62.0 0.276 T -91.5 -26.6 62.0 0.276 0.0 MAN
 8.102
 NH2
 O4
ARG I:54 E:54 59.0 0.262 T -91.6 -26.6 59.0 0.262 0.0 MAN
 7.986
 NH2
 O4
ARG N:54 F:54 61.0 0.271 T -91.5 -26.6 61.0 0.271 0.0 MAN
 8.213
 NH2
 O4
6edu 3 P01730 99.46 6e-129 EM
 2018-10-17 ARG G:54 G:54 51.0 0.227 S -81.0 -8.9 38.0 0.169 0.058 K:None:0.058
ARG H:54 H:54 53.0 0.236 S -81.0 -8.8 37.0 0.164 0.072 O:None:0.071
ARG I:54 I:54 52.0 0.231 S -80.9 -8.9 37.0 0.164 0.067 M:None:0.067
2nxy 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 B:1054 17.0 0.076 G -116.7 6.4 17.0 0.076 0.0 HOH
 2.885
 NH2
 O
2nxz 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 B:1054 18.0 0.08 G -125.1 7.0 18.0 0.08 0.0 HOH
 3.497
 CD
 O
2ny0 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 B:1054 12.0 0.053 G -102.6 2.4 12.0 0.053 0.0 HOH
 2.837
 NH2
 O
2ny1 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 B:1054 18.0 0.08 G -124.2 2.2 18.0 0.08 0.0 HOH
 2.629
 NH2
 O
2ny2 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 B:1054 15.0 0.067 G -118.7 9.2 15.0 0.067 0.0 HOH
 3.049
 NE
 O
2ny3 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 B:1054 15.0 0.067 G -117.3 1.4 15.0 0.067 0.0 HOH
 5.195
 N
 O
2ny4 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 B:1054 15.0 0.067 G -121.1 3.6 15.0 0.067 0.0 HOH
 2.791
 O
 O
2ny5 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 C:1054 24.0 0.107 G -104.7 9.4 24.0 0.107 0.0 HOH
 2.908
 NH2
 O
2ny6 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ARG B:55 B:1054 22.0 0.098 G -111.3 -8.2 22.0 0.098 0.0
3jwd 2 P01730 100.0 7e-129 X-RAY
 2009-12-29 ARG B:55 C:1054 20.0 0.089 T -108.5 -13.2 20.0 0.089 0.0 HOH
 4.141
 NH2
 O
ARG F:55 D:1054 18.0 0.08 T -114.9 20.1 NA NA NA
3jwo 2 P01730 100.0 7e-129 X-RAY
 2009-12-29 ARG B:55 C:1054 20.0 0.089 T -108.7 -13.2 20.0 0.089 0.0
4r2g 2 P01730 100.0 7e-129 X-RAY
 2014-10-08 ARG B:55 F:54 23.0 0.102 T -121.9 -17.0 23.0 0.102 0.0
ARG E:55 B:54 34.0 0.151 T -95.0 2.0 NA NA NA
ARG H:55 H:54 45.0 0.2 T -87.5 -7.9 NA NA NA
ARG K:55 L:54 48.0 0.213 T -119.0 -27.0 NA NA NA
5cay 2 P01730 100.0 7e-129 X-RAY
 2015-12-09 ARG B:55 B:54 34.0 0.151 S -73.3 -31.8 34.0 0.151 0.0
3o2d 3 P01730 100.0 3e-128 X-RAY
 2010-12-22 ARG C:54 A:54 32.0 0.142 G -101.3 -6.6 32.0 0.142 0.0 HOH
 3.877
 NH2
 O
3cd4 1 P01730 100.0 3e-128 X-RAY
 1993-10-31 ARG A:54 A:54 48.0 0.213 T -115.7 -1.0 48.0 0.213 0.0 HOH
 3.083
 NH2
 O
3lqa 1 P01730 100.0 4e-128 X-RAY
 2010-04-07 ARG A:54 C:54 42.0 0.187 T 60.0 20.0 30.0 0.133 0.054 D:None:0.053
5thr 3 P01730 100.0 4e-128 EM
 2016-11-16 ARG G:54 G:54 37.0 0.164 T -94.5 -52.8 37.0 0.164 0.0
ARG H:54 H:54 36.0 0.16 T -94.5 -52.9 36.0 0.16 0.0
ARG I:54 I:54 37.0 0.164 T -95.8 -53.0 37.0 0.164 0.0
6cm3 3 P01730 100.0 4e-128 EM
 2018-10-17 ARG G:54 G:54 39.0 0.173 T -104.5 -4.5 39.0 0.173 0.0
ARG H:54 H:54 39.0 0.173 T -104.5 -4.5 39.0 0.173 0.0
ARG I:54 I:54 37.0 0.164 T -104.5 -4.5 37.0 0.164 0.0
6u0l 2 P01730 100.0 4e-128 EM
 2019-12-11 ARG D:54 D:54 45.0 0.2 T -103.4 -26.4 45.0 0.2 0.0
ARG E:54 E:54 44.0 0.196 T -103.4 -26.4 44.0 0.196 0.0
ARG F:54 F:54 43.0 0.191 T -103.4 -26.4 43.0 0.191 0.0
6u0n 2 P01730 100.0 4e-128 EM
 2019-12-11 ARG D:54 D:54 36.0 0.16 S -119.5 20.5 36.0 0.16 0.0
ARG E:54 E:54 27.0 0.12 T -120.3 -1.6 27.0 0.12 0.0
ARG F:54 F:54 13.0 0.058 T -119.2 -48.9 13.0 0.058 0.0
2b4c 2 P01730 100.0 2e-127 X-RAY
 2005-11-15 ARG B:54 C:54 28.0 0.124 T -118.3 21.2 28.0 0.124 0.0
2qad 2 P01730 100.0 2e-127 X-RAY
 2007-09-25 ARG B:54 B:54 32.0 0.142 T -78.2 -18.2 32.0 0.142 0.0
ARG F:54 F:54 33.0 0.147 T -78.2 -18.2 NA NA NA
5a7x 2 P01730 100.0 2e-127 EM
 2015-08-05 ARG B:54 B:54 19.0 0.084 G -128.5 -5.3 19.0 0.084 0.0
ARG F:54 F:54 20.0 0.089 G -128.6 -5.3 20.0 0.089 0.0
ARG J:54 J:54 19.0 0.084 G -128.5 -5.4 19.0 0.084 0.0
4p9h 1 P01730 99.45 3e-127 X-RAY
 2014-05-21 ARG A:54 C:54 36.0 0.16 S 62.1 12.8 36.0 0.16 0.0 NAG
NAG
 4.928
9.099
 CD
CD
 O5
C1
6opn 3 P01730 98.37 8e-126 EM
 2020-10-21 ARG C:74 C:54 43.0 0.191 T -126.1 -30.7 43.0 0.191 0.0
ARG F:74 F:54 43.0 0.191 T -126.1 -30.8 43.0 0.191 0.0
ARG I:74 I:54 45.0 0.2 T -126.0 -30.7 45.0 0.2 0.0
6opo 4 P01730 98.37 8e-126 EM
 2020-10-21 ARG D:74 C:54 27.0 0.12 T -125.7 -28.4 27.0 0.12 0.0
ARG I:74 G:54 28.0 0.124 T -125.7 -28.4 28.0 0.124 0.0
ARG N:74 N:54 27.0 0.12 T -125.7 -28.4 27.0 0.12 0.0
6opp 4 P01730 98.37 8e-126 EM
 2020-10-21 ARG D:74 C:54 30.0 0.133 T -126.3 -24.6 30.0 0.133 0.0 MAN
 7.936
 NH2
 O6
ARG M:74 M:54 32.0 0.142 T -123.5 -28.0 32.0 0.142 0.0 MAN
 8.122
 NH2
 O6
ARG O:74 F:54 60.0 0.267 T -87.2 -31.3 60.0 0.267 0.0 MAN
 7.513
 NH1
 O4
6opq 4 P01730 98.37 8e-126 EM
 2020-10-21 ARG D:74 C:54 60.0 0.267 T -119.1 -30.1 60.0 0.267 0.0
ARG I:74 I:54 60.0 0.267 T -119.1 -30.1 60.0 0.267 0.0
ARG N:74 J:54 60.0 0.267 T -119.1 -30.1 60.0 0.267 0.0
6x5b 4 P01730 98.37 8e-126 EM
 2020-10-21 ARG D:74 C:54 55.0 0.244 S 55.1 34.5 55.0 0.244 0.0
ARG I:74 G:54 56.0 0.249 S 55.1 34.6 56.0 0.249 0.0
ARG N:74 N:54 56.0 0.249 S 55.1 34.5 56.0 0.249 0.0
6x5c 3 P01730 98.37 8e-126 EM
 2020-10-21 ARG C:74 C:54 47.0 0.209 S 52.2 40.9 47.0 0.209 0.0
ARG F:74 I:54 50.0 0.222 S 52.0 41.5 50.0 0.222 0.0
ARG I:74 J:54 58.0 0.258 S 57.5 38.1 58.0 0.258 0.0
1cdi 1 P01730 100.0 6e-125 X-RAY
 1994-04-30 ARG A:55 A:54 43.0 0.191 T -119.2 -15.7 43.0 0.191 0.0
1cdh 1 P01730 100.0 7e-125 X-RAY
 1994-04-30 ARG A:54 A:54 30.0 0.133 T -118.0 -0.4 30.0 0.133 0.0 HOH
 3.901
 NE
 O
1cdj 1 P01730 100.0 7e-125 X-RAY
 1997-04-01 ARG A:54 A:54 26.0 0.116 G -151.5 3.1 26.0 0.116 0.0 HOH
 4.163
 NH2
 O
1jl4 4 P01730 100.0 7e-125 X-RAY
 2001-09-19 ARG D:54 D:54 21.0 NA T -115.8 -0.9 21.0 NA NA
4r4h 2 P01730 100.0 7e-125 X-RAY
 2014-09-17 ARG B:54 B:54 15.0 0.067 G -129.3 18.1 15.0 0.067 0.0
6l1y 2 P01730 100.0 4e-124 X-RAY
 2020-05-20 ARG B:54 C:54 18.0 0.08 G -126.5 -14.0 18.0 0.08 0.0 HOH
 3.602
 CA
 O
1cdy 1 P01730 99.44 6e-124 X-RAY
 1997-04-01 ARG A:54 A:54 26.0 0.116 G -133.0 -1.8 26.0 0.116 0.0 HOH
 2.652
 NE
 O
1cdu 1 P01730 99.44 8e-124 X-RAY
 1997-04-01 ARG A:54 A:54 25.0 0.111 T -127.1 -14.7 25.0 0.111 0.0 HOH
 3.387
 CD
 O
6meo 2 P01730 100.0 2e-123 EM
 2018-12-12 ARG B:54 A:54 62.0 0.276 T -123.5 -34.3 62.0 0.276 0.0
3jcb 4 P01730 100.0 7e-123 EM
 2017-05-10 ARG D:54 D:54 28.0 0.124 T -118.3 21.2 28.0 0.124 0.0
3jcc 4 P01730 100.0 7e-123 EM
 2017-05-10 ARG D:54 D:54 33.0 0.147 T -122.9 -11.2 33.0 0.147 0.0
3s4s 4 P01730 98.88 9e-123 X-RAY
 2011-09-21 ARG D:58 G:54 31.0 0.138 S -94.6 3.2 31.0 0.138 0.0 HOH
 7.955
 O
 O
ARG H:58 H:54 25.0 0.111 -111.9 0.2 NA NA NA
3s5l 4 P01730 97.74 3e-119 X-RAY
 2011-09-21 ARG G:58 G:54 25.0 0.111 -86.6 6.4 25.0 0.111 0.0 HOH
 3.312
 N
 O
ARG H:58 H:54 24.0 0.107 -88.7 11.1 NA NA NA
6tyb 2 F6XGD3 87.64 3e-101 X-RAY
 2019-10-02 ARG B:54 C:54 40.0 0.178 G -102.4 9.2 40.0 0.178 0.0 MAN
HOH
 9.598
2.845
 NH2
O
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01730-f1 1 P01730 100.0 0.0 ARG A:79 A:79 19.0 0.084 T -115.2 -12.5