Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6923331 . G A CCDS8562.1:NM_000616.4:c.238Gct>Act_NP_000607.1:p.80A>T Homo sapiens CD4 molecule (CD4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7t0o 4 P01730 100.0 0.0 EM
 2022-01-12 ALA G:55 H:55 16.0 0.139 E -64.9 144.4 16.0 0.139 0.0
ALA I:55 L:55 9.0 0.078 E -71.3 154.2 9.0 0.078 0.0
ALA K:55 M:55 9.0 0.078 E -71.2 154.1 9.0 0.078 0.0
7t0r 3 P01730 99.73 0.0 X-RAY
 2022-01-12 ALA C:55 A:55 16.0 0.139 E -72.0 146.1 16.0 0.139 0.0
ALA F:55 D:55 10.0 0.087 E -77.9 154.4 NA NA NA
1wio 1 P01730 100.0 0.0 X-RAY
 1997-07-07 ALA A:55 A:55 0.0 0.0 E -103.9 156.5 0.0 0.0 0.0
ALA B:55 B:55 0.0 0.0 E -108.1 155.5 NA NA NA
1wip 1 P01730 100.0 0.0 X-RAY
 1997-07-07 ALA A:55 A:55 0.0 0.0 E -103.9 156.5 0.0 0.0 0.0
ALA B:55 B:55 0.0 0.0 E -108.1 155.5 NA NA NA
1wiq 1 P01730 100.0 0.0 X-RAY
 1997-07-07 ALA A:55 A:55 0.0 0.0 E -103.9 156.5 0.0 0.0 0.0
ALA B:55 B:55 0.0 0.0 E -108.2 155.5 NA NA NA
5u1f 5 P01730 100.0 0.0 EM
 2017-02-22 ALA I:55 M:1055 32.0 0.278 E -98.5 141.8 32.0 0.278 0.0
6met 2 P01730 100.0 0.0 EM
 2018-12-12 ALA B:55 A:55 1.0 0.009 E -81.1 140.2 1.0 0.009 0.0
3t0e 5 P01730 99.45 0.0 X-RAY
 2012-03-07 ALA E:55 E:55 2.0 0.017 E -109.5 148.2 2.0 0.017 0.0
4q6i 3 P01730 100.0 1e-148 X-RAY
 2014-07-23 ALA C:80 C:55 1.0 0.009 E -106.4 141.1 NA NA NA
ALA I:80 I:55 2.0 0.017 E -105.9 142.2 NA NA NA
ALA J:80 J:55 1.0 0.009 E -105.6 141.5 NA NA NA
ALA K:80 K:55 2.0 0.017 E -106.4 141.5 2.0 0.017 0.0
1g9m 2 P01730 99.46 6e-129 X-RAY
 2000-12-27 ALA B:55 C:55 0.0 0.0 E -106.2 145.4 0.0 0.0 0.0 HOH
 4.969
 CB
 O
1g9n 2 P01730 99.46 6e-129 X-RAY
 2000-12-27 ALA B:55 C:55 0.0 0.0 E -99.6 151.3 0.0 0.0 0.0 HOH
 4.719
 O
 O
1gc1 2 P01730 99.46 6e-129 X-RAY
 1998-07-08 ALA B:55 C:55 0.0 0.0 E -84.8 137.0 0.0 0.0 0.0 HOH
 3.721
 O
 O
1rzj 2 P01730 99.46 6e-129 X-RAY
 2004-02-03 ALA B:55 C:55 1.0 0.009 E -110.5 146.1 1.0 0.009 0.0 HOH
 4.872
 CB
 O
1rzk 2 P01730 99.46 6e-129 X-RAY
 2004-02-03 ALA B:55 C:55 1.0 0.009 E -87.3 163.2 1.0 0.009 0.0 HOH
 4.969
 O
 O
3j70 3 P01730 99.46 6e-129 EM
 2015-08-26 ALA C:55 C:55 0.0 0.0 E -92.1 132.5 0.0 0.0 0.0
ALA H:55 O:55 0.0 0.0 E -92.1 132.5 0.0 0.0 0.0
ALA M:55 T:55 0.0 0.0 E -92.0 132.4 0.0 0.0 0.0
4h8w 4 P01730 99.46 6e-129 X-RAY
 2014-04-09 ALA D:55 C:55 3.0 0.026 E -103.6 136.7 3.0 0.026 0.0 HOH
 3.788
 C
 O
4jm2 6 P01730 99.46 6e-129 X-RAY
 2013-05-29 ALA F:55 F:55 1.0 0.009 E -108.1 136.0 1.0 0.009 0.0
4rqs 1 P01730 99.46 6e-129 X-RAY
 2014-12-31 ALA A:55 B:55 2.0 0.017 E -113.8 143.2 2.0 0.017 0.0
5a8h 2 P01730 99.46 6e-129 EM
 2015-08-05 ALA B:55 B:55 0.0 0.0 E -87.3 163.3 0.0 0.0 0.0
ALA H:55 H:55 0.0 0.0 E -87.3 163.2 0.0 0.0 0.0
ALA N:55 N:55 0.0 0.0 E -87.3 163.2 0.0 0.0 0.0
5vn3 4 P01730 99.46 6e-129 EM
 2017-07-12 ALA D:55 C:55 1.0 0.009 E -75.9 143.3 1.0 0.009 0.0
ALA I:55 E:55 1.0 0.009 E -76.0 143.3 1.0 0.009 0.0
ALA N:55 F:55 2.0 0.017 E -76.1 143.3 2.0 0.017 0.0
6edu 3 P01730 99.46 6e-129 EM
 2018-10-17 ALA G:55 G:55 0.0 0.0 E -83.5 142.7 0.0 0.0 0.0
ALA H:55 H:55 0.0 0.0 E -83.4 142.7 0.0 0.0 0.0
ALA I:55 I:55 1.0 0.009 E -83.5 142.7 1.0 0.009 0.0
2nxy 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 B:1055 1.0 0.009 E -109.4 138.2 1.0 0.009 0.0 HOH
 3.626
 O
 O
2nxz 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 B:1055 2.0 0.017 E -109.5 141.8 2.0 0.017 0.0 IPA
HOH
 8.802
5.012
 O
CB
 O2
O
2ny0 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 B:1055 2.0 0.017 E -106.2 144.4 2.0 0.017 0.0 HOH
 4.915
 CB
 O
2ny1 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 B:1055 1.0 0.009 E -102.7 145.7 1.0 0.009 0.0 HOH
 5.044
 CB
 O
2ny2 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 B:1055 2.0 0.017 E -107.1 141.4 2.0 0.017 0.0 HOH
 3.834
 C
 O
2ny3 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 B:1055 1.0 0.009 E -105.2 143.3 1.0 0.009 0.0 HOH
 5.038
 CB
 O
2ny4 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 B:1055 2.0 0.017 E -103.6 142.6 2.0 0.017 0.0 HOH
 3.848
 C
 O
2ny5 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 C:1055 2.0 0.017 E -106.0 140.0 2.0 0.017 0.0 HOH
 4.945
 CB
 O
2ny6 2 P01730 100.0 7e-129 X-RAY
 2007-02-06 ALA B:56 B:1055 0.0 0.0 E -86.3 158.3 0.0 0.0 0.0 HOH
 8.821
 O
 O
3jwd 2 P01730 100.0 7e-129 X-RAY
 2009-12-29 ALA B:56 C:1055 1.0 0.009 B -99.3 139.7 1.0 0.009 0.0 HOH
 4.452
 O
 O
ALA F:56 D:1055 3.0 0.026 E -122.3 138.5 NA NA NA
3jwo 2 P01730 100.0 7e-129 X-RAY
 2009-12-29 ALA B:56 C:1055 2.0 0.017 B -99.2 139.8 2.0 0.017 0.0
4r2g 2 P01730 100.0 7e-129 X-RAY
 2014-10-08 ALA B:56 F:55 1.0 0.009 E -73.2 152.1 1.0 0.009 0.0
ALA E:56 B:55 1.0 0.009 E -106.1 126.7 NA NA NA
ALA H:56 H:55 1.0 0.009 E -97.4 145.4 NA NA NA
ALA K:56 L:55 1.0 0.009 E -75.8 139.8 NA NA NA
5cay 2 P01730 100.0 7e-129 X-RAY
 2015-12-09 ALA B:56 B:55 0.0 0.0 E -77.4 131.9 0.0 0.0 0.0
3o2d 3 P01730 100.0 3e-128 X-RAY
 2010-12-22 ALA C:55 A:55 0.0 0.0 E -99.7 139.8 0.0 0.0 0.0 HOH
 9.348
 O
 O
3cd4 1 P01730 100.0 3e-128 X-RAY
 1993-10-31 ALA A:55 A:55 4.0 0.035 E -102.8 170.7 4.0 0.035 0.0 HOH
 2.885
 O
 O
3lqa 1 P01730 100.0 4e-128 X-RAY
 2010-04-07 ALA A:55 C:55 3.0 0.026 E -121.1 114.4 3.0 0.026 0.0
5thr 3 P01730 100.0 4e-128 EM
 2016-11-16 ALA G:55 G:55 3.0 0.026 E -73.6 145.9 3.0 0.026 0.0
ALA H:55 H:55 3.0 0.026 E -73.5 145.9 3.0 0.026 0.0
ALA I:55 I:55 3.0 0.026 E -73.5 146.3 3.0 0.026 0.0
6cm3 3 P01730 100.0 4e-128 EM
 2018-10-17 ALA G:55 G:55 2.0 0.017 E -97.4 150.5 2.0 0.017 0.0
ALA H:55 H:55 2.0 0.017 E -97.4 150.4 2.0 0.017 0.0
ALA I:55 I:55 2.0 0.017 E -97.4 150.4 2.0 0.017 0.0
6u0l 2 P01730 100.0 4e-128 EM
 2019-12-11 ALA D:55 D:55 1.0 0.009 E -74.8 159.8 1.0 0.009 0.0
ALA E:55 E:55 0.0 0.0 E -74.7 159.7 0.0 0.0 0.0
ALA F:55 F:55 1.0 0.009 E -74.7 159.8 1.0 0.009 0.0
6u0n 2 P01730 100.0 4e-128 EM
 2019-12-11 ALA D:55 D:55 4.0 0.035 E -127.9 150.5 4.0 0.035 0.0
ALA E:55 E:55 4.0 0.035 E -111.6 143.1 4.0 0.035 0.0
ALA F:55 F:55 1.0 0.009 E -81.3 150.7 1.0 0.009 0.0
2b4c 2 P01730 100.0 2e-127 X-RAY
 2005-11-15 ALA B:55 C:55 0.0 0.0 E -117.8 141.5 0.0 0.0 0.0
2qad 2 P01730 100.0 2e-127 X-RAY
 2007-09-25 ALA B:55 B:55 2.0 0.017 -77.7 166.1 2.0 0.017 0.0
ALA F:55 F:55 3.0 0.026 -77.7 166.8 NA NA NA
5a7x 2 P01730 100.0 2e-127 EM
 2015-08-05 ALA B:55 B:55 0.0 0.0 E -87.3 163.2 0.0 0.0 0.0
ALA F:55 F:55 0.0 0.0 E -87.3 163.2 0.0 0.0 0.0
ALA J:55 J:55 0.0 0.0 E -87.3 163.3 0.0 0.0 0.0
4p9h 1 P01730 99.45 3e-127 X-RAY
 2014-05-21 ALA A:55 C:55 0.0 0.0 E -129.0 129.6 0.0 0.0 0.0
6opn 3 P01730 98.37 8e-126 EM
 2020-10-21 ALA C:75 C:55 8.0 0.07 E -81.9 152.0 8.0 0.07 0.0
ALA F:75 F:55 8.0 0.07 E -81.8 152.0 8.0 0.07 0.0
ALA I:75 I:55 7.0 0.061 E -81.9 152.0 7.0 0.061 0.0
6opo 4 P01730 98.37 8e-126 EM
 2020-10-21 ALA D:75 C:55 1.0 0.009 E -80.2 141.2 1.0 0.009 0.0
ALA I:75 G:55 2.0 0.017 E -80.2 141.2 2.0 0.017 0.0
ALA N:75 N:55 2.0 0.017 E -80.2 141.2 2.0 0.017 0.0
6opp 4 P01730 98.37 8e-126 EM
 2020-10-21 ALA D:75 C:55 1.0 0.009 E -75.2 142.3 1.0 0.009 0.0
ALA M:75 M:55 2.0 0.017 E -73.1 139.7 2.0 0.017 0.0
ALA O:75 F:55 2.0 0.017 E -73.9 140.5 2.0 0.017 0.0
6opq 4 P01730 98.37 8e-126 EM
 2020-10-21 ALA D:75 C:55 3.0 0.026 E -81.4 143.8 3.0 0.026 0.0
ALA I:75 I:55 3.0 0.026 E -81.5 143.8 3.0 0.026 0.0
ALA N:75 J:55 3.0 0.026 E -81.4 143.8 3.0 0.026 0.0
6x5b 4 P01730 98.37 8e-126 EM
 2020-10-21 ALA D:75 C:55 7.0 0.061 E -151.5 148.1 7.0 0.061 0.0
ALA I:75 G:55 7.0 0.061 E -151.5 148.1 7.0 0.061 0.0
ALA N:75 N:55 7.0 0.061 E -151.6 148.1 7.0 0.061 0.0
6x5c 3 P01730 98.37 8e-126 EM
 2020-10-21 ALA C:75 C:55 7.0 0.061 E -144.0 150.7 7.0 0.061 0.0
ALA F:75 I:55 10.0 0.087 E -145.8 143.4 10.0 0.087 0.0
ALA I:75 J:55 8.0 0.07 E -132.0 145.4 8.0 0.07 0.0
1cdi 1 P01730 100.0 6e-125 X-RAY
 1994-04-30 ALA A:56 A:55 0.0 0.0 E -88.7 152.6 0.0 0.0 0.0
1cdh 1 P01730 100.0 7e-125 X-RAY
 1994-04-30 ALA A:55 A:55 2.0 0.017 E -107.6 143.6 2.0 0.017 0.0 HOH
 5.723
 O
 O
1cdj 1 P01730 100.0 7e-125 X-RAY
 1997-04-01 ALA A:55 A:55 2.0 0.017 E -99.5 159.7 2.0 0.017 0.0 HOH
 4.207
 O
 O
1jl4 4 P01730 100.0 7e-125 X-RAY
 2001-09-19 ALA D:55 D:55 2.0 0.017 E -102.8 170.8 2.0 0.017 0.0
4r4h 2 P01730 100.0 7e-125 X-RAY
 2014-09-17 ALA B:55 B:55 3.0 0.026 E -119.9 140.1 3.0 0.026 0.0
6l1y 2 P01730 100.0 4e-124 X-RAY
 2020-05-20 ALA B:55 C:55 0.0 0.0 E -75.3 143.4 0.0 0.0 0.0 HOH
 3.575
 O
 O
1cdy 1 P01730 99.44 6e-124 X-RAY
 1997-04-01 ALA A:55 A:55 3.0 0.026 E -98.9 144.0 3.0 0.026 0.0 HOH
 2.819
 CB
 O
1cdu 1 P01730 99.44 8e-124 X-RAY
 1997-04-01 ALA A:55 A:55 0.0 0.0 E -86.3 136.3 0.0 0.0 0.0 HOH
 7.861
 O
 O
6meo 2 P01730 100.0 2e-123 EM
 2018-12-12 ALA B:55 A:55 1.0 0.009 E -81.1 140.2 1.0 0.009 0.0
3jcb 4 P01730 100.0 7e-123 EM
 2017-05-10 ALA D:55 D:55 0.0 0.0 E -117.8 141.4 0.0 0.0 0.0
3jcc 4 P01730 100.0 7e-123 EM
 2017-05-10 ALA D:55 D:55 1.0 0.009 E -81.9 150.6 1.0 0.009 0.0
3s4s 4 P01730 98.88 9e-123 X-RAY
 2011-09-21 ALA D:59 G:55 2.0 0.017 E -107.4 147.2 2.0 0.017 0.0
ALA H:59 H:55 3.0 0.026 E -102.7 152.6 NA NA NA
3s5l 4 P01730 97.74 3e-119 X-RAY
 2011-09-21 ALA G:59 G:55 2.0 0.017 E -101.9 153.1 2.0 0.017 0.0 HOH
 2.994
 N
 O
ALA H:59 H:55 2.0 0.017 E -110.9 145.2 NA NA NA
6tyb 2 F6XGD3 87.64 3e-101 X-RAY
 2019-10-02 ALA B:55 C:55 1.0 0.009 E -108.2 145.9 1.0 0.009 0.0 HOH
 3.726
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01730-f1 1 P01730 100.0 0.0 ALA A:80 A:80 1.0 0.009 E -90.2 140.9