Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6924122 . A C CCDS8562.1:NM_000616.4:c.571Aag>Cag_NP_000607.1:p.191K>Q Homo sapiens CD4 molecule (CD4), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7t0o 4 P01730 100.0 0.0 EM
2022-01-12 LYS G:166 H:166 107.0 0.535 E -92.0 145.0 107.0 0.535 0.0
LYS I:166 L:166 112.0 0.56 -93.8 145.1 112.0 0.56 0.0
LYS K:166 M:166 112.0 0.56 -93.6 145.1 112.0 0.56 0.0
7t0r 3 P01730 99.73 0.0 X-RAY
2022-01-12 LYS C:166 A:166 112.0 0.56 E -111.8 138.2 98.0 0.49 0.07 B:None:0.07
LYS F:166 D:166 40.0 NA E -114.0 137.0 NA NA NA
1wio 1 P01730 100.0 0.0 X-RAY
1997-07-07 LYS A:166 A:166 82.0 0.41 E -111.3 163.0 82.0 0.41 0.0
LYS B:166 B:166 85.0 0.425 E -112.5 164.5 NA NA NA
1wip 1 P01730 100.0 0.0 X-RAY
1997-07-07 LYS A:166 A:166 80.0 0.4 E -111.4 163.0 80.0 0.4 0.0
LYS B:166 B:166 85.0 0.425 E -112.5 164.5 NA NA NA
1wiq 1 P01730 100.0 0.0 X-RAY
1997-07-07 LYS A:166 A:166 84.0 0.42 E -111.3 163.0 84.0 0.42 0.0
LYS B:166 B:166 85.0 0.425 E -112.6 164.5 NA NA NA
5u1f 5 P01730 100.0 0.0 EM
2017-02-22 LYS I:166 M:1166 33.0 NA E -91.3 156.2 33.0 NA NA
6met 2 P01730 100.0 0.0 EM
2018-12-12 LYS B:166 A:166 96.0 0.48 B -130.9 143.2 96.0 0.48 0.0
3t0e 5 P01730 99.45 0.0 X-RAY
2012-03-07 LYS E:166 E:166 70.0 0.35 E -137.5 123.3 70.0 0.35 0.0
4q6i 3 P01730 100.0 1e-148 X-RAY
2014-07-23 LYS C:191 C:166 106.0 0.53 E -90.5 164.2 NA NA NA
LYS I:191 I:166 108.0 0.54 E -90.3 164.7 NA NA NA
LYS J:191 J:166 109.0 0.545 E -91.1 164.9 NA NA NA
LYS K:191 K:166 104.0 0.52 E -90.3 164.1 104.0 0.52 0.0
1g9m 2 P01730 99.46 6e-129 X-RAY
2000-12-27 LYS B:166 C:166 88.0 0.44 E -104.6 167.9 88.0 0.44 0.0 HOH
2.827
CA
O
1g9n 2 P01730 99.46 6e-129 X-RAY
2000-12-27 LYS B:166 C:166 78.0 0.39 B -117.7 169.8 78.0 0.39 0.0 HOH
2.949
NZ
O
1gc1 2 P01730 99.46 6e-129 X-RAY
1998-07-08 LYS B:166 C:166 74.0 0.37 E -110.4 157.8 74.0 0.37 0.0 HOH
3.075
NZ
O
1rzj 2 P01730 99.46 6e-129 X-RAY
2004-02-03 LYS B:166 C:166 91.0 0.455 E -103.5 175.4 91.0 0.455 0.0 HOH
3.986
CA
O
1rzk 2 P01730 99.46 6e-129 X-RAY
2004-02-03 LYS B:166 C:166 75.0 0.375 E -113.8 167.7 75.0 0.375 0.0 HOH
2.791
NZ
O
3j70 3 P01730 99.46 6e-129 EM
2015-08-26 LYS C:166 C:166 78.0 0.39 E -128.6 144.0 78.0 0.39 0.0
LYS H:166 O:166 78.0 0.39 E -128.6 144.0 78.0 0.39 0.0
LYS M:166 T:166 79.0 0.395 E -128.5 144.0 79.0 0.395 0.0
4h8w 4 P01730 99.46 6e-129 X-RAY
2014-04-09 LYS D:166 C:166 94.0 0.47 E -132.6 154.8 94.0 0.47 0.0 HOH
3.229
CE
O
4jm2 6 P01730 99.46 6e-129 X-RAY
2013-05-29 LYS F:166 F:166 98.0 0.49 E -120.2 155.4 98.0 0.49 0.0
4rqs 1 P01730 99.46 6e-129 X-RAY
2014-12-31 LYS A:166 B:166 83.0 0.415 E -81.9 153.8 83.0 0.415 0.0
5a8h 2 P01730 99.46 6e-129 EM
2015-08-05 LYS B:166 B:166 77.0 0.385 E -113.7 167.8 77.0 0.385 0.0
LYS H:166 H:166 76.0 0.38 E -113.7 167.7 76.0 0.38 0.0
LYS N:166 N:166 76.0 0.38 E -113.8 167.8 76.0 0.38 0.0
5vn3 4 P01730 99.46 6e-129 EM
2017-07-12 LYS D:166 C:166 104.0 0.52 E -133.4 125.3 104.0 0.52 0.0
LYS I:166 E:166 105.0 0.525 E -133.4 125.4 105.0 0.525 0.0
LYS N:166 F:166 105.0 0.525 E -133.4 125.5 105.0 0.525 0.0
6edu 3 P01730 99.46 6e-129 EM
2018-10-17 LYS G:166 NA:NA DO NA DO DO DO NA NA NA
LYS H:166 NA:NA DO NA DO DO DO NA NA NA
LYS I:166 NA:NA DO NA DO DO DO NA NA NA
2nxy 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 B:1166 94.0 0.47 E -95.9 156.9 94.0 0.47 0.0 HOH
3.517
CD
O
2nxz 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 B:1166 89.0 0.445 E -78.0 158.3 89.0 0.445 0.0 HOH
3.148
CA
O
2ny0 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 B:1166 85.0 0.425 E -71.1 151.0 85.0 0.425 0.0 HOH
3.570
CA
O
2ny1 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 B:1166 85.0 0.425 E -90.5 161.3 85.0 0.425 0.0 HOH
3.059
CA
O
2ny2 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 B:1166 103.0 0.515 E -107.2 156.8 103.0 0.515 0.0 HOH
4.192
CD
O
2ny3 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 B:1166 91.0 0.455 E -88.1 159.9 91.0 0.455 0.0 HOH
3.407
CA
O
2ny4 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 B:1166 101.0 0.505 E -98.0 153.5 101.0 0.505 0.0 HOH
3.800
CG
O
2ny5 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 C:1166 112.0 0.56 E -103.2 155.4 112.0 0.56 0.0 HOH
7.518
N
O
2ny6 2 P01730 100.0 7e-129 X-RAY
2007-02-06 LYS B:167 B:1166 101.0 0.505 E -134.4 140.9 101.0 0.505 0.0
3jwd 2 P01730 100.0 7e-129 X-RAY
2009-12-29 LYS B:167 C:1166 143.0 0.715 E -117.3 175.6 143.0 0.715 0.0 HOH
5.240
CD
O
LYS F:167 D:1166 120.0 0.6 E -125.3 177.1 NA NA NA
3jwo 2 P01730 100.0 7e-129 X-RAY
2009-12-29 LYS B:167 C:1166 145.0 0.725 E -117.2 175.7 145.0 0.725 0.0
4r2g 2 P01730 100.0 7e-129 X-RAY
2014-10-08 LYS B:167 F:166 92.0 0.46 E -114.1 152.7 92.0 0.46 0.0
LYS E:167 B:166 87.0 0.435 E -121.9 147.3 NA NA NA
LYS H:167 H:166 113.0 0.565 E -122.9 144.7 NA NA NA
LYS K:167 L:166 70.0 0.35 E -129.6 143.4 NA NA NA
5cay 2 P01730 100.0 7e-129 X-RAY
2015-12-09 LYS B:167 B:166 159.0 0.795 -102.6 166.2 159.0 0.795 0.0
3o2d 3 P01730 100.0 3e-128 X-RAY
2010-12-22 LYS C:166 A:166 98.0 0.49 E -120.1 144.6 84.0 0.42 0.07 B:None:0.07
HOH
5.398
CE
O
3cd4 1 P01730 100.0 3e-128 X-RAY
1993-10-31 LYS A:166 A:166 66.0 0.33 E -83.3 169.5 25.0 0.125 0.205 A:P01730:0.205
HOH
3.352
CD
O
3lqa 1 P01730 100.0 4e-128 X-RAY
2010-04-07 LYS A:166 C:166 103.0 0.515 E -126.3 147.1 103.0 0.515 0.0
5thr 3 P01730 100.0 4e-128 EM
2016-11-16 LYS G:166 NA:NA DO NA DO DO DO NA NA NA
LYS H:166 NA:NA DO NA DO DO DO NA NA NA
LYS I:166 NA:NA DO NA DO DO DO NA NA NA
6cm3 3 P01730 100.0 4e-128 EM
2018-10-17 LYS G:166 NA:NA DO NA DO DO DO NA NA NA
LYS H:166 NA:NA DO NA DO DO DO NA NA NA
LYS I:166 NA:NA DO NA DO DO DO NA NA NA
6u0l 2 P01730 100.0 4e-128 EM
2019-12-11 LYS D:166 NA:NA DO NA DO DO DO NA NA NA
LYS E:166 NA:NA DO NA DO DO DO NA NA NA
LYS F:166 NA:NA DO NA DO DO DO NA NA NA
6u0n 2 P01730 100.0 4e-128 EM
2019-12-11 LYS D:166 NA:NA DO NA DO DO DO NA NA NA
LYS E:166 NA:NA DO NA DO DO DO NA NA NA
LYS F:166 NA:NA DO NA DO DO DO NA NA NA
2b4c 2 P01730 100.0 2e-127 X-RAY
2005-11-15 LYS B:166 C:166 101.0 0.505 E -124.3 138.1 101.0 0.505 0.0
2qad 2 P01730 100.0 2e-127 X-RAY
2007-09-25 LYS B:166 B:166 97.0 0.485 -132.3 141.9 97.0 0.485 0.0 MLA
3.025
CE
O3B
LYS F:166 F:166 80.0 0.4 -133.4 142.0 NA NA NA
5a7x 2 P01730 100.0 2e-127 EM
2015-08-05 LYS B:166 B:166 78.0 0.39 E -113.8 167.8 78.0 0.39 0.0
LYS F:166 F:166 75.0 0.375 E -113.7 167.7 75.0 0.375 0.0
LYS J:166 J:166 76.0 0.38 E -113.8 167.8 76.0 0.38 0.0
4p9h 1 P01730 99.45 3e-127 X-RAY
2014-05-21 LYS A:166 C:166 32.0 NA E -130.2 125.5 32.0 NA NA
6opn 3 P01730 98.37 8e-126 EM
2020-10-21 LYS C:186 NA:NA DO NA DO DO DO NA NA NA
LYS F:186 NA:NA DO NA DO DO DO NA NA NA
LYS I:186 NA:NA DO NA DO DO DO NA NA NA
6opo 4 P01730 98.37 8e-126 EM
2020-10-21 LYS D:186 NA:NA DO NA DO DO DO NA NA NA
LYS I:186 NA:NA DO NA DO DO DO NA NA NA
LYS N:186 NA:NA DO NA DO DO DO NA NA NA
6opp 4 P01730 98.37 8e-126 EM
2020-10-21 LYS D:186 NA:NA DO NA DO DO DO NA NA NA
LYS M:186 NA:NA DO NA DO DO DO NA NA NA
LYS O:186 NA:NA DO NA DO DO DO NA NA NA
6opq 4 P01730 98.37 8e-126 EM
2020-10-21 LYS D:186 NA:NA DO NA DO DO DO NA NA NA
LYS I:186 NA:NA DO NA DO DO DO NA NA NA
LYS N:186 NA:NA DO NA DO DO DO NA NA NA
6x5b 4 P01730 98.37 8e-126 EM
2020-10-21 LYS D:186 NA:NA DO NA DO DO DO NA NA NA
LYS I:186 NA:NA DO NA DO DO DO NA NA NA
LYS N:186 NA:NA DO NA DO DO DO NA NA NA
6x5c 3 P01730 98.37 8e-126 EM
2020-10-21 LYS C:186 NA:NA DO NA DO DO DO NA NA NA
LYS F:186 NA:NA DO NA DO DO DO NA NA NA
LYS I:186 NA:NA DO NA DO DO DO NA NA NA
1cdi 1 P01730 100.0 6e-125 X-RAY
1994-04-30 LYS A:167 A:166 78.0 0.39 -54.2 134.1 27.0 0.135 0.255 A:P01730:0.255
1cdh 1 P01730 100.0 7e-125 X-RAY
1994-04-30 LYS A:166 A:166 84.0 0.42 -62.7 168.2 15.0 0.075 0.345 A:P01730:0.345
HOH
4.945
CD
O
1cdj 1 P01730 100.0 7e-125 X-RAY
1997-04-01 LYS A:166 A:166 100.0 0.5 E -178.3 150.5 100.0 0.5 0.0 HOH
3.881
C
O
1jl4 4 P01730 100.0 7e-125 X-RAY
2001-09-19 LYS D:166 D:166 73.0 0.365 E -83.3 169.6 73.0 0.365 0.0
4r4h 2 P01730 100.0 7e-125 X-RAY
2014-09-17 LYS B:166 B:166 93.0 0.465 E -77.1 168.4 93.0 0.465 0.0
6l1y 2 P01730 100.0 4e-124 X-RAY
2020-05-20 LYS B:166 C:166 118.0 0.59 71.6 118.5 118.0 0.59 0.0 HOH
6.558
NZ
O
1cdy 1 P01730 99.44 6e-124 X-RAY
1997-04-01 LYS A:166 A:166 92.0 0.46 E -91.7 163.1 92.0 0.46 0.0 HOH
3.552
CD
O
1cdu 1 P01730 99.44 8e-124 X-RAY
1997-04-01 LYS A:166 A:166 84.0 0.42 E -95.0 172.0 84.0 0.42 0.0 HOH
4.601
NZ
O
6meo 2 P01730 100.0 2e-123 EM
2018-12-12 LYS B:166 A:166 96.0 0.48 B -130.9 143.2 96.0 0.48 0.0
3jcb 4 P01730 100.0 7e-123 EM
2017-05-10 LYS D:166 D:166 101.0 0.505 E -124.3 138.1 101.0 0.505 0.0
3jcc 4 P01730 100.0 7e-123 EM
2017-05-10 LYS D:166 D:166 115.0 0.575 E -116.6 154.7 115.0 0.575 0.0
3s4s 4 P01730 98.88 9e-123 X-RAY
2011-09-21 LYS D:170 G:166 85.0 0.425 E -109.5 161.2 85.0 0.425 0.0
LYS H:170 H:166 90.0 0.45 E -121.5 152.6 NA NA NA
3s5l 4 P01730 97.74 3e-119 X-RAY
2011-09-21 LYS G:170 G:166 106.0 0.53 E -130.1 159.0 106.0 0.53 0.0 HOH
6.905
O
O
LYS H:170 H:166 85.0 0.425 E -101.4 152.2 NA NA NA
6tyb 2 F6XGD3 87.64 3e-101 X-RAY
2019-10-02 LYS B:166 C:166 79.0 0.395 E -104.2 156.8 79.0 0.395 0.0 HOH
6.768
NZ
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01730-f1 1 P01730 100.0 0.0 LYS A:191 A:191 111.0 0.555 E -95.3 154.2