Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6924146 . A C CCDS8562.1:NM_000616.4:c.595Atc>Ctc_NP_000607.1:p.199I>L Homo sapiens CD4 molecule (CD4), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7t0o 4 P01730 100.0 0.0 EM
2022-01-12 ILE G:174 H:174 6.0 0.034 -128.8 129.1 5.0 0.029 0.005 H:None:0.006
ILE I:174 L:174 12.0 0.069 -129.0 127.6 9.0 0.051 0.018 J:None:0.017
ILE K:174 M:174 12.0 0.069 -128.9 127.6 9.0 0.051 0.018 L:None:0.017
7t0r 3 P01730 99.73 0.0 X-RAY
2022-01-12 ILE C:174 A:174 5.0 0.029 -121.4 129.3 4.0 0.023 0.006 G:None:0.006
ILE F:174 D:174 7.0 0.04 -123.5 125.8 NA NA NA
1wio 1 P01730 100.0 0.0 X-RAY
1997-07-07 ILE A:174 A:174 4.0 0.023 E -139.3 106.4 4.0 0.023 0.0
ILE B:174 B:174 4.0 0.023 E -135.8 106.8 NA NA NA
1wip 1 P01730 100.0 0.0 X-RAY
1997-07-07 ILE A:174 A:174 5.0 0.029 E -139.3 106.4 5.0 0.029 0.0
ILE B:174 B:174 5.0 0.029 E -135.8 106.8 NA NA NA
1wiq 1 P01730 100.0 0.0 X-RAY
1997-07-07 ILE A:174 A:174 5.0 0.029 E -139.3 106.4 5.0 0.029 0.0
ILE B:174 B:174 4.0 0.023 E -135.7 106.9 NA NA NA
5u1f 5 P01730 100.0 0.0 EM
2017-02-22 ILE I:174 M:1174 52.0 NA E -114.3 127.3 52.0 NA NA
6met 2 P01730 100.0 0.0 EM
2018-12-12 ILE B:174 A:174 23.0 0.131 -123.5 119.8 23.0 0.131 0.0
3t0e 5 P01730 99.45 0.0 X-RAY
2012-03-07 ILE E:174 E:174 26.0 0.149 -130.7 -61.9 26.0 0.149 0.0
4q6i 3 P01730 100.0 1e-148 X-RAY
2014-07-23 ILE C:199 C:174 12.0 0.069 E -129.1 136.9 NA NA NA
ILE I:199 I:174 11.0 0.063 E -128.2 137.6 NA NA NA
ILE J:199 J:174 12.0 0.069 E -128.5 137.4 NA NA NA
ILE K:199 K:174 13.0 0.074 E -128.2 137.4 13.0 0.074 0.0
1g9m 2 P01730 99.46 6e-129 X-RAY
2000-12-27 ILE B:174 C:174 4.0 0.023 E -128.5 154.7 4.0 0.023 0.0 HOH
3.955
CD1
O
1g9n 2 P01730 99.46 6e-129 X-RAY
2000-12-27 ILE B:174 C:174 5.0 0.029 -128.6 143.0 5.0 0.029 0.0
1gc1 2 P01730 99.46 6e-129 X-RAY
1998-07-08 ILE B:174 C:174 1.0 0.006 E -115.3 143.1 1.0 0.006 0.0 HOH
4.973
CD1
O
1rzj 2 P01730 99.46 6e-129 X-RAY
2004-02-03 ILE B:174 C:174 3.0 0.017 E -136.2 152.9 3.0 0.017 0.0 HOH
4.351
CD1
O
1rzk 2 P01730 99.46 6e-129 X-RAY
2004-02-03 ILE B:174 C:174 5.0 0.029 -127.4 140.6 5.0 0.029 0.0
3j70 3 P01730 99.46 6e-129 EM
2015-08-26 ILE C:174 C:174 0.0 0.0 E -115.0 129.3 0.0 0.0 0.0
ILE H:174 O:174 0.0 0.0 E -115.0 129.3 0.0 0.0 0.0
ILE M:174 T:174 0.0 0.0 E -115.0 129.3 0.0 0.0 0.0
4h8w 4 P01730 99.46 6e-129 X-RAY
2014-04-09 ILE D:174 C:174 2.0 0.011 E -115.9 143.5 2.0 0.011 0.0 HOH
7.100
CD1
O
4jm2 6 P01730 99.46 6e-129 X-RAY
2013-05-29 ILE F:174 F:174 40.0 0.229 -173.4 134.2 40.0 0.229 0.0
4rqs 1 P01730 99.46 6e-129 X-RAY
2014-12-31 ILE A:174 B:174 4.0 0.023 E -118.4 127.0 4.0 0.023 0.0
5a8h 2 P01730 99.46 6e-129 EM
2015-08-05 ILE B:174 B:174 5.0 0.029 -127.4 140.6 5.0 0.029 0.0
ILE H:174 H:174 6.0 0.034 -127.4 140.7 6.0 0.034 0.0
ILE N:174 N:174 5.0 0.029 -127.4 140.6 5.0 0.029 0.0
5vn3 4 P01730 99.46 6e-129 EM
2017-07-12 ILE D:174 C:174 26.0 0.149 -129.3 108.8 26.0 0.149 0.0
ILE I:174 E:174 27.0 0.154 -129.2 108.8 27.0 0.154 0.0
ILE N:174 F:174 26.0 0.149 -129.3 108.8 26.0 0.149 0.0
6edu 3 P01730 99.46 6e-129 EM
2018-10-17 ILE G:174 NA:NA DO NA DO DO DO NA NA NA
ILE H:174 NA:NA DO NA DO DO DO NA NA NA
ILE I:174 NA:NA DO NA DO DO DO NA NA NA
2nxy 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 B:1174 9.0 0.051 E -118.2 134.7 9.0 0.051 0.0 HOH
3.208
O
O
2nxz 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 B:1174 7.0 0.04 E -121.7 128.3 7.0 0.04 0.0 HOH
3.447
CD1
O
2ny0 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 B:1174 8.0 0.046 E -117.5 135.4 8.0 0.046 0.0 HOH
5.183
CA
O
2ny1 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 B:1174 2.0 0.011 E -122.0 128.8 2.0 0.011 0.0 HOH
4.087
CD1
O
2ny2 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 B:1174 9.0 0.051 E -120.7 130.6 9.0 0.051 0.0 HOH
3.033
O
O
2ny3 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 B:1174 9.0 0.051 E -119.1 135.5 9.0 0.051 0.0 HOH
3.099
O
O
2ny4 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 B:1174 10.0 0.057 E -116.4 135.2 10.0 0.057 0.0 HOH
3.759
CA
O
2ny5 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 C:1174 11.0 0.063 E -100.9 132.3 11.0 0.063 0.0 HOH
3.934
CA
O
2ny6 2 P01730 100.0 7e-129 X-RAY
2007-02-06 ILE B:175 B:1174 9.0 0.051 E -101.3 143.4 9.0 0.051 0.0 HOH
3.945
CD1
O
3jwd 2 P01730 100.0 7e-129 X-RAY
2009-12-29 ILE B:175 C:1174 12.0 0.069 E -98.3 123.8 12.0 0.069 0.0 HOH
8.797
O
O
ILE F:175 D:1174 14.0 0.08 -90.7 132.3 NA NA NA
3jwo 2 P01730 100.0 7e-129 X-RAY
2009-12-29 ILE B:175 C:1174 13.0 0.074 E -98.4 123.8 13.0 0.074 0.0
4r2g 2 P01730 100.0 7e-129 X-RAY
2014-10-08 ILE B:175 F:174 16.0 0.091 E -122.4 158.0 16.0 0.091 0.0
ILE E:175 B:174 17.0 0.097 E -137.1 141.1 NA NA NA
ILE H:175 H:174 11.0 0.063 -120.7 143.9 NA NA NA
ILE K:175 L:174 18.0 0.103 E -127.2 143.4 NA NA NA
5cay 2 P01730 100.0 7e-129 X-RAY
2015-12-09 ILE B:175 B:174 214.0 1.0 -120.4 360.0 214.0 1.0 0.0
3o2d 3 P01730 100.0 3e-128 X-RAY
2010-12-22 ILE C:174 A:174 3.0 0.017 E -128.7 128.6 3.0 0.017 0.0 HOH
6.590
CD1
O
3cd4 1 P01730 100.0 3e-128 X-RAY
1993-10-31 ILE A:174 A:174 14.0 0.08 E -104.1 136.2 14.0 0.08 0.0
3lqa 1 P01730 100.0 4e-128 X-RAY
2010-04-07 ILE A:174 C:174 36.0 0.206 -120.1 127.9 36.0 0.206 0.0
5thr 3 P01730 100.0 4e-128 EM
2016-11-16 ILE G:174 NA:NA DO NA DO DO DO NA NA NA
ILE H:174 NA:NA DO NA DO DO DO NA NA NA
ILE I:174 NA:NA DO NA DO DO DO NA NA NA
6cm3 3 P01730 100.0 4e-128 EM
2018-10-17 ILE G:174 NA:NA DO NA DO DO DO NA NA NA
ILE H:174 NA:NA DO NA DO DO DO NA NA NA
ILE I:174 NA:NA DO NA DO DO DO NA NA NA
6u0l 2 P01730 100.0 4e-128 EM
2019-12-11 ILE D:174 NA:NA DO NA DO DO DO NA NA NA
ILE E:174 NA:NA DO NA DO DO DO NA NA NA
ILE F:174 NA:NA DO NA DO DO DO NA NA NA
6u0n 2 P01730 100.0 4e-128 EM
2019-12-11 ILE D:174 NA:NA DO NA DO DO DO NA NA NA
ILE E:174 NA:NA DO NA DO DO DO NA NA NA
ILE F:174 NA:NA DO NA DO DO DO NA NA NA
2b4c 2 P01730 100.0 2e-127 X-RAY
2005-11-15 ILE B:174 C:174 20.0 0.114 E -123.0 125.3 20.0 0.114 0.0
2qad 2 P01730 100.0 2e-127 X-RAY
2007-09-25 ILE B:174 B:174 9.0 0.051 E -131.1 122.9 9.0 0.051 0.0
ILE F:174 F:174 9.0 0.051 E -131.5 124.2 NA NA NA
5a7x 2 P01730 100.0 2e-127 EM
2015-08-05 ILE B:174 B:174 5.0 0.029 -127.4 140.7 5.0 0.029 0.0
ILE F:174 F:174 6.0 0.034 -127.5 140.7 6.0 0.034 0.0
ILE J:174 J:174 5.0 0.029 -127.4 140.7 5.0 0.029 0.0
4p9h 1 P01730 99.45 3e-127 X-RAY
2014-05-21 ILE A:174 C:174 41.0 0.234 -134.5 -175.9 41.0 0.234 0.0
6opn 3 P01730 98.37 8e-126 EM
2020-10-21 ILE C:194 NA:NA DO NA DO DO DO NA NA NA
ILE F:194 NA:NA DO NA DO DO DO NA NA NA
ILE I:194 NA:NA DO NA DO DO DO NA NA NA
6opo 4 P01730 98.37 8e-126 EM
2020-10-21 ILE D:194 NA:NA DO NA DO DO DO NA NA NA
ILE I:194 NA:NA DO NA DO DO DO NA NA NA
ILE N:194 NA:NA DO NA DO DO DO NA NA NA
6opp 4 P01730 98.37 8e-126 EM
2020-10-21 ILE D:194 NA:NA DO NA DO DO DO NA NA NA
ILE M:194 NA:NA DO NA DO DO DO NA NA NA
ILE O:194 NA:NA DO NA DO DO DO NA NA NA
6opq 4 P01730 98.37 8e-126 EM
2020-10-21 ILE D:194 NA:NA DO NA DO DO DO NA NA NA
ILE I:194 NA:NA DO NA DO DO DO NA NA NA
ILE N:194 NA:NA DO NA DO DO DO NA NA NA
6x5b 4 P01730 98.37 8e-126 EM
2020-10-21 ILE D:194 NA:NA DO NA DO DO DO NA NA NA
ILE I:194 NA:NA DO NA DO DO DO NA NA NA
ILE N:194 NA:NA DO NA DO DO DO NA NA NA
6x5c 3 P01730 98.37 8e-126 EM
2020-10-21 ILE C:194 NA:NA DO NA DO DO DO NA NA NA
ILE F:194 NA:NA DO NA DO DO DO NA NA NA
ILE I:194 NA:NA DO NA DO DO DO NA NA NA
1cdi 1 P01730 100.0 6e-125 X-RAY
1994-04-30 ILE A:175 A:174 5.0 0.029 E -118.6 139.5 5.0 0.029 0.0
1cdh 1 P01730 100.0 7e-125 X-RAY
1994-04-30 ILE A:174 A:174 3.0 0.017 -108.2 131.6 3.0 0.017 0.0 HOH
3.595
O
O
1cdj 1 P01730 100.0 7e-125 X-RAY
1997-04-01 ILE A:174 A:174 2.0 0.011 -126.0 157.0 2.0 0.011 0.0 HOH
3.642
CD1
O
1jl4 4 P01730 100.0 7e-125 X-RAY
2001-09-19 ILE D:174 D:174 12.0 0.069 E -104.1 136.1 12.0 0.069 0.0
4r4h 2 P01730 100.0 7e-125 X-RAY
2014-09-17 ILE B:174 B:174 11.0 0.063 E -118.1 123.0 11.0 0.063 0.0
6l1y 2 P01730 100.0 4e-124 X-RAY
2020-05-20 ILE B:174 C:174 7.0 0.04 E -122.7 141.5 7.0 0.04 0.0 HOH
8.734
CG2
O
1cdy 1 P01730 99.44 6e-124 X-RAY
1997-04-01 ILE A:174 A:174 2.0 0.011 E -86.7 117.9 2.0 0.011 0.0 HOH
2.759
CA
O
1cdu 1 P01730 99.44 8e-124 X-RAY
1997-04-01 ILE A:174 A:174 1.0 0.006 E -106.7 116.9 1.0 0.006 0.0 HOH
5.246
O
O
6meo 2 P01730 100.0 2e-123 EM
2018-12-12 ILE B:174 A:174 22.0 0.126 -123.5 124.2 22.0 0.126 0.0
3jcb 4 P01730 100.0 7e-123 EM
2017-05-10 ILE D:174 D:174 21.0 0.12 E -123.1 125.3 21.0 0.12 0.0
3jcc 4 P01730 100.0 7e-123 EM
2017-05-10 ILE D:174 D:174 16.0 0.091 E -124.6 141.5 16.0 0.091 0.0
3s4s 4 P01730 98.88 9e-123 X-RAY
2011-09-21 ILE D:178 G:174 19.0 0.109 E -107.9 145.3 19.0 0.109 0.0
ILE H:178 H:174 24.0 0.137 E -90.8 127.2 NA NA NA
3s5l 4 P01730 97.74 3e-119 X-RAY
2011-09-21 ILE G:178 G:174 18.0 0.103 E -105.1 151.0 18.0 0.103 0.0
ILE H:178 H:174 19.0 0.109 E -123.9 138.2 NA NA NA
6tyb 2 F6XGD3 87.64 3e-101 X-RAY
2019-10-02 ILE B:174 C:174 30.0 0.171 E -127.5 146.5 30.0 0.171 0.0 HOH
3.971
CD1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01730-f1 1 P01730 100.0 0.0 ILE A:199 A:199 1.0 0.006 E -119.7 129.3