Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6976809 . G A CCDS53740.1:NM_001159287.1:c.190Ggc>Agc_NP_001152759.1:p.64G>S Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 GLY A:30 A:26 36.0 0.48 H -60.2 -47.1 36.0 0.48 0.0 HOH
 2.714
 O
 O
GLY B:30 B:26 36.0 0.48 H -62.4 -40.7 36.0 0.48 0.0 HOH
 2.656
 O
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 GLY A:30 A:26 39.0 0.52 H -55.4 -44.7 39.0 0.52 0.0 HOH
 2.672
 O
 O
GLY B:30 B:26 38.0 0.507 H -55.0 -39.4 38.0 0.507 0.0 HOH
 2.570
 O
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 GLY A:32 A:26 38.0 0.507 H -54.0 -41.6 38.0 0.507 0.0 HOH
 2.830
 O
 O
GLY B:32 B:26 38.0 0.507 H -56.6 -42.1 38.0 0.507 0.0 HOH
 2.729
 O
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 GLY A:27 A:26 37.0 0.493 H -59.0 -38.9 37.0 0.493 0.0 HOH
 4.135
 N
 O
GLY B:27 B:26 38.0 0.507 H -59.7 -38.2 NA NA NA
GLY C:27 C:26 39.0 0.52 H -59.6 -38.9 NA NA NA
GLY D:27 D:26 38.0 0.507 H -59.6 -38.6 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 GLY A:32 A:26 37.0 0.493 H -57.5 -41.0 37.0 0.493 0.0 HOH
 2.906
 HA3
 O
GLY B:32 B:26 37.0 0.493 H -54.2 -38.1 37.0 0.493 0.0 HOH
 2.855
 O
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 GLY A:28 A:26 34.0 0.453 H -64.0 -43.0 34.0 0.453 0.0 HOH
 2.701
 O
 O
GLY B:28 B:26 44.0 0.587 H -56.6 -33.7 44.0 0.587 0.0 HOH
 6.562
 O
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 GLY A:28 A:26 39.0 0.52 H -54.8 -48.8 39.0 0.52 0.0 HOH
 2.742
 O
 O
GLY B:28 B:26 39.0 0.52 H -56.0 -47.6 39.0 0.52 0.0 HOH
 2.650
 O
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 GLY A:30 A:26 40.0 0.533 H -58.9 -45.0 40.0 0.533 0.0 HOH
 2.651
 O
 O
GLY B:30 B:26 36.0 0.48 H -51.8 -50.4 36.0 0.48 0.0 HOH
 2.828
 O
 O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 GLY A:30 A:26 38.0 0.507 H -60.2 -43.9 38.0 0.507 0.0 HOH
 2.677
 O
 O
GLY B:30 B:26 35.0 0.467 H -62.3 -40.1 35.0 0.467 0.0 HOH
 3.453
 O
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 GLY A:26 A:26 40.0 0.533 H -53.5 -55.1 40.0 0.533 0.0
GLY B:26 B:26 40.0 0.533 H -67.6 -47.3 40.0 0.533 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 GLY A:32 A:26 39.0 0.52 H -59.4 -39.8 39.0 0.52 0.0 HOH
 2.644
 O
 O
GLY B:32 B:26 38.0 0.507 H -58.9 -41.5 38.0 0.507 0.0 HOH
 2.852
 O
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 GLY A:28 A:26 39.0 0.52 H -61.9 -41.9 39.0 0.52 0.0 HOH
 2.750
 O
 O
GLY B:28 B:26 37.0 0.493 H -59.7 -44.0 37.0 0.493 0.0 HOH
 2.691
 O
 O
GLY C:28 C:26 36.0 0.48 H -58.1 -40.8 NA NA NA
GLY D:28 D:26 40.0 0.533 H -51.1 -38.6 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 GLY A:28 A:26 35.0 0.467 H -60.1 -41.5 35.0 0.467 0.0 HOH
 3.326
 C
 O
GLY B:28 B:26 39.0 0.52 H -59.7 -43.9 39.0 0.52 0.0 HOH
 2.756
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 GLY A:26 A:26 38.0 0.507 H -57.4 -43.2 38.0 0.507 0.0 HOH
 2.735
 O
 O
GLY B:26 B:26 39.0 0.52 H -59.1 -47.8 39.0 0.52 0.0 HOH
 2.741
 O
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 GLY A:24 A:26 36.0 0.48 H -57.9 -40.0 36.0 0.48 0.0 HOH
 3.293
 O
 O
GLY B:24 B:26 37.0 0.493 H -56.0 -44.4 37.0 0.493 0.0 HOH
 2.612
 O
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 GLY A:24 A:26 38.0 0.507 H -55.5 -48.5 38.0 0.507 0.0 HOH
 3.618
 N
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 GLY B:24 B:26 38.0 0.507 H -56.2 -47.2 38.0 0.507 0.0 HOH
 2.787
 O
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 THR A:26 A:26 94.0 0.671 H -55.4 -44.4 94.0 0.671 0.0 HOH
 2.586
 OG1
 O
THR B:26 B:26 95.0 0.679 H -57.5 -41.6 95.0 0.679 0.0 HOH
 2.624
 O
 O
THR C:26 C:26 96.0 0.686 H -54.7 -43.1 NA NA NA
THR D:26 D:26 95.0 0.679 H -58.3 -43.6 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 THR A:26 A:26 97.0 0.693 H -62.0 -37.8 97.0 0.693 0.0
THR B:26 B:26 97.0 0.693 H -63.4 -38.2 97.0 0.693 0.0
THR C:26 C:26 99.0 0.707 H -62.2 -38.7 NA NA NA
THR D:26 D:26 98.0 0.7 H -63.9 -33.4 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 THR A:26 A:26 93.0 0.664 H -58.5 -40.6 93.0 0.664 0.0 HOH
 2.815
 O
 O
THR B:26 B:26 87.0 0.621 H -59.4 -40.2 87.0 0.621 0.0 HOH
 2.904
 O
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 THR A:26 A:26 83.0 0.593 H -58.9 -44.9 83.0 0.593 0.0 HOH
 2.485
 O
 O
THR B:26 B:26 95.0 0.679 H -60.3 -43.9 95.0 0.679 0.0 HOH
 2.715
 O
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 GLY A:23 A:26 39.0 0.52 H -61.6 -42.1 39.0 0.52 0.0 HOH
 2.618
 O
 O
GLY B:23 E:26 37.0 0.493 H -61.1 -45.7 37.0 0.493 0.0 HOH
 3.099
 HA2
 O
GLY C:23 B:26 37.0 0.493 H -60.9 -49.5 NA NA NA
GLY D:23 C:26 38.0 0.507 H -55.9 -44.0 NA NA NA
GLY E:23 D:26 39.0 0.52 H -60.9 -39.6 NA NA NA
GLY F:23 F:26 38.0 0.507 H -57.4 -45.3 NA NA NA
GLY G:23 G:26 38.0 0.507 H -59.0 -41.9 NA NA NA
GLY H:23 H:26 36.0 0.48 H -59.0 -41.6 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 HIS A:26 A:26 151.0 0.774 H -58.7 -42.5 151.0 0.774 0.0 HOH
 3.500
 CD2
 O
HIS B:26 B:26 145.0 0.744 H -59.5 -44.1 145.0 0.744 0.0 HOH
 3.228
 ND1
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 HIS A:25 1:26 145.0 0.744 H -57.5 -45.5 145.0 0.744 0.0 HOH
 4.044
 N
 O
HIS B:25 2:26 148.0 0.759 H -60.2 -37.3 148.0 0.759 0.0 HOH
 2.834
 O
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 HIS A:25 A:26 145.0 0.744 H -59.0 -51.2 145.0 0.744 0.0 HOH
 2.758
 NE2
 O
HIS B:25 B:26 131.0 0.672 H -54.0 -58.9 131.0 0.672 0.0 HOH
 7.653
 N
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 HIS A:26 A:26 140.0 0.718 H -57.2 -41.6 140.0 0.718 0.0 HOH
 3.149
 ND1
 O
HIS B:26 B:26 143.0 0.733 H -55.8 -41.8 143.0 0.733 0.0 HOH
 6.021
 C
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 HIS A:25 A:26 145.0 0.744 H -60.9 -46.2 145.0 0.744 0.0 HOH
 3.241
 NE2
 O
HIS B:25 B:26 141.0 0.723 H -53.0 -45.8 141.0 0.723 0.0 HOH
 2.708
 O
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 HIS A:25 1:26 150.0 0.769 H -58.6 -47.4 150.0 0.769 0.0 HOH
 4.075
 N
 O
HIS B:25 2:26 151.0 0.774 H -60.2 -38.5 151.0 0.774 0.0 HOH
 2.729
 ND1
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 HIS A:26 A:26 149.0 0.764 H -52.5 -49.0 149.0 0.764 0.0 HOH
 3.040
 CD2
 O
HIS B:26 B:26 147.0 0.754 H -58.1 -37.4 147.0 0.754 0.0 HOH
 2.542
 O
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 HIS A:25 A:26 152.0 0.779 H -62.4 -37.5 152.0 0.779 0.0 HOH
 4.604
 O
 O
HIS B:25 B:26 144.0 0.738 H -64.9 -33.5 144.0 0.738 0.0 HOH
 2.829
 ND1
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 HIS A:25 A:26 153.0 0.785 H -62.6 -44.7 153.0 0.785 0.0 HOH
 4.499
 CB
 O
HIS B:25 B:26 146.0 0.749 H -64.3 -36.0 146.0 0.749 0.0 HOH
 2.909
 ND1
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 HIS A:26 A:26 145.0 0.744 H -58.6 -42.2 145.0 0.744 0.0 HOH
 2.871
 O
 O
HIS B:26 B:26 138.0 0.708 H -53.7 -47.2 138.0 0.708 0.0 HOH
 2.709
 ND1
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 HIS A:25 1:26 146.0 0.749 H -57.5 -46.1 146.0 0.749 0.0 HOH
 3.242
 NE2
 O
HIS B:25 2:26 147.0 0.754 H -60.1 -39.2 147.0 0.754 0.0 HOH
 3.501
 ND1
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 HIS A:25 A:26 143.0 0.733 H -71.3 -31.7 143.0 0.733 0.0 HOH
 3.747
 CB
 O
HIS B:25 B:26 146.0 0.749 H -59.1 -37.6 146.0 0.749 0.0 HOH
 2.962
 CE1
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 HIS A:25 A:26 142.0 0.728 H -62.3 -29.5 142.0 0.728 0.0 HOH
 3.181
 NE2
 O
HIS B:25 B:26 140.0 0.718 H -69.1 -41.6 140.0 0.718 0.0 HOH
 2.936
 ND1
 O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 HIS A:25 A:26 145.0 0.744 H -62.9 -37.6 145.0 0.744 0.0 HOH
 2.710
 ND1
 O
HIS B:25 B:26 142.0 0.728 H -59.5 -34.7 142.0 0.728 0.0 HOH
 3.767
 N
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 HIS A:25 A:26 148.0 0.759 H -62.9 -41.0 148.0 0.759 0.0 HOH
 2.866
 O
 O
HIS B:25 B:26 146.0 0.749 H -60.2 -37.8 146.0 0.749 0.0 HOH
 2.860
 ND1
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 HIS A:25 A:26 142.0 0.728 H -55.4 -42.6 142.0 0.728 0.0 HOH
 2.895
 ND1
 O
HIS B:25 B:26 149.0 0.764 H -52.9 -44.9 149.0 0.764 0.0 HOH
 8.455
 N
 O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 HIS A:25 A:26 110.0 0.564 H -42.6 -58.1 110.0 0.564 0.0
HIS B:25 B:26 107.0 0.549 H -41.2 -62.4 107.0 0.549 0.0
2iam 3 P60174 93.33 1.0 X-RAY
 2007-04-03 GLY C:5 P:27 69.0 0.92 -97.8 156.6 0.0 0.0 0.92 D:P01848:0.427
B:P04229:0.587
A:P01903:0.147
 HOH
 6.709
 O
 O
2ian 3 P60174 100.0 1.0 X-RAY
 2007-04-03 GLY C:5 C:27 68.0 0.907 -92.0 177.8 0.0 0.0 0.907 D:P01848:0.427
B:P04229:0.52
A:P01903:0.187
 HOH
 7.755
 N
 O
GLY H:5 H:27 72.0 0.96 -87.6 153.7 NA NA NA
GLY M:5 M:27 71.0 0.947 -94.5 149.7 NA NA NA
GLY R:5 R:27 70.0 0.933 -89.9 153.5 NA NA NA
4e41 3 P60174 93.33 1.0 X-RAY
 2012-08-29 GLY C:5 C:27 69.0 0.92 -88.7 157.4 1.0 0.013 0.907 B:P04229:0.6
D:None:0.253
A:P01903:0.16
 HOH
 4.787
 CA
 O
GLY H:5 H:27 72.0 0.96 -84.2 152.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 GLY A:27 A:27 41.0 0.547 H -57.6 -43.0