Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6976831 . T A CCDS53740.1:NM_001159287.1:c.212gTg>gAg_NP_001152759.1:p.71V>E Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:37 A:33 38.0 0.245 -77.7 130.7 38.0 0.245 0.0 HOH
 2.706
 O
 O
VAL B:37 B:33 39.0 0.252 -80.2 122.9 39.0 0.252 0.0 HOH
 3.384
 O
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 VAL A:37 A:33 23.0 0.148 -88.8 125.4 23.0 0.148 0.0 HOH
 2.592
 O
 O
VAL B:37 B:33 37.0 0.239 -94.4 122.9 37.0 0.239 0.0 HOH
 3.338
 N
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 VAL A:39 A:33 16.0 0.103 -102.2 125.3 16.0 0.103 0.0 HOH
 3.546
 HG21
 O
VAL B:39 B:33 24.0 0.155 -62.4 141.8 24.0 0.155 0.0 HOH
 3.178
 HG13
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 VAL A:34 A:33 35.0 0.226 -80.3 122.4 35.0 0.226 0.0 HOH
 7.062
 CG1
 O
VAL B:34 B:33 32.0 0.206 -81.4 122.4 NA NA NA
VAL C:34 C:33 38.0 0.245 -78.1 122.2 NA NA NA
VAL D:34 D:33 41.0 0.265 -80.5 122.0 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 VAL A:39 A:33 30.0 0.194 -73.5 122.5 30.0 0.194 0.0 NA
HOH
 9.805
2.998
 HB
O
 NA
O
VAL B:39 B:33 26.0 0.168 -54.8 147.3 26.0 0.168 0.0 HOH
 2.334
 H
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 VAL A:35 A:33 33.0 0.213 -76.4 136.7 33.0 0.213 0.0 HOH
 3.200
 CG2
 O
VAL B:35 B:33 38.0 0.245 -97.7 103.7 38.0 0.245 0.0 HOH
 4.755
 CG2
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 VAL A:35 A:33 39.0 0.252 -79.5 125.4 39.0 0.252 0.0 HOH
 2.826
 O
 O
VAL B:35 B:33 51.0 0.329 -87.6 126.4 51.0 0.329 0.0 HOH
 3.017
 N
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:37 A:33 33.0 0.213 -85.9 126.8 33.0 0.213 0.0 HOH
 2.855
 N
 O
VAL B:37 B:33 24.0 0.155 -84.8 124.5 24.0 0.155 0.0 HOH
 4.490
 CG2
 O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 VAL A:37 A:33 35.0 0.226 -111.5 112.0 35.0 0.226 0.0 HOH
 3.029
 CG2
 O
VAL B:37 B:33 23.0 0.148 -82.8 127.2 23.0 0.148 0.0 HOH
 2.775
 N
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 VAL A:33 A:33 42.0 0.271 -81.8 142.7 42.0 0.271 0.0
VAL B:33 B:33 47.0 0.303 -103.3 119.1 47.0 0.303 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 VAL A:39 A:33 32.0 0.206 -77.6 124.3 32.0 0.206 0.0 NA
HOH
 7.361
1.894
 HB
H
 NA
O
VAL B:39 B:33 36.0 0.232 -77.8 138.6 36.0 0.232 0.0 HOH
 4.115
 HG21
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 VAL A:35 A:33 31.0 0.2 -94.1 119.9 31.0 0.2 0.0 HOH
 4.651
 C
 O
VAL B:35 B:33 47.0 0.303 -83.5 122.9 47.0 0.303 0.0 HOH
 3.047
 CG1
 O
VAL C:35 C:33 28.0 0.181 -83.0 116.4 NA NA NA
VAL D:35 D:33 32.0 0.206 -100.1 127.0 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:35 A:33 35.0 0.226 -76.3 122.7 35.0 0.226 0.0 HOH
 2.922
 O
 O
VAL B:35 B:33 35.0 0.226 -101.0 116.7 35.0 0.226 0.0 HOH
 3.083
 N
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 VAL A:33 A:33 46.0 0.297 -79.8 127.8 46.0 0.297 0.0 HOH
 2.948
 N
 O
VAL B:33 B:33 29.0 0.187 -80.0 121.9 29.0 0.187 0.0 HOH
 2.709
 O
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 VAL A:31 A:33 30.0 0.194 -86.1 132.4 30.0 0.194 0.0 HOH
 4.510
 CG2
 O
VAL B:31 B:33 50.0 0.323 -127.7 141.1 50.0 0.323 0.0 HOH
 2.795
 O
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL A:31 A:33 32.0 0.206 -73.3 127.5 32.0 0.206 0.0 HOH
 2.729
 N
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 VAL B:31 B:33 37.0 0.239 -85.7 133.1 37.0 0.239 0.0 HOH
 2.967
 N
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:33 A:33 29.0 0.187 -95.0 117.4 29.0 0.187 0.0 HOH
 3.111
 N
 O
VAL B:33 B:33 37.0 0.239 -80.5 119.6 37.0 0.239 0.0 HOH
 4.151
 CG1
 O
VAL C:33 C:33 38.0 0.245 -76.9 115.7 NA NA NA
VAL D:33 D:33 37.0 0.239 -87.9 128.7 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:33 A:33 38.0 0.245 -96.6 116.4 38.0 0.245 0.0 HOH
 6.780
 C
 O
VAL B:33 B:33 37.0 0.239 -94.2 116.4 37.0 0.239 0.0 HOH
 5.948
 C
 O
VAL C:33 C:33 38.0 0.245 -95.2 116.9 NA NA NA
VAL D:33 D:33 38.0 0.245 -95.1 116.5 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 VAL A:33 A:33 29.0 0.187 -94.0 124.8 29.0 0.187 0.0 HOH
 4.150
 CG2
 O
VAL B:33 B:33 28.0 0.181 -92.7 126.5 28.0 0.181 0.0 HOH
 4.128
 CG1
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 VAL A:33 A:33 38.0 0.245 -81.9 117.6 38.0 0.245 0.0 HOH
 2.694
 O
 O
VAL B:33 B:33 31.0 0.2 -83.1 118.8 31.0 0.2 0.0 HOH
 3.246
 CG1
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 VAL A:30 A:33 30.0 0.194 -81.8 121.4 30.0 0.194 0.0 HOH
 2.409
 O
 O
VAL B:30 E:33 40.0 0.258 -89.6 131.7 40.0 0.258 0.0 HOH
 3.273
 HG11
 O
VAL C:30 B:33 31.0 0.2 -82.4 122.9 NA NA NA
VAL D:30 C:33 42.0 0.271 -86.6 116.8 NA NA NA
VAL E:30 D:33 33.0 0.213 -80.3 116.3 NA NA NA
VAL F:30 F:33 49.0 0.316 -97.0 130.3 NA NA NA
VAL G:30 G:33 31.0 0.2 -75.7 120.0 NA NA NA
VAL H:30 H:33 42.0 0.271 -84.1 133.1 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 LEU A:33 A:33 46.0 0.271 -99.1 130.4 46.0 0.271 0.0 HOH
 2.366
 O
 O
LEU B:33 B:33 29.0 0.171 -101.4 132.4 29.0 0.171 0.0 HOH
 3.057
 O
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 LEU A:32 1:33 45.0 0.265 -98.1 142.2 45.0 0.265 0.0 HOH
 3.685
 CB
 O
LEU B:32 2:33 10.0 0.059 -103.1 139.0 10.0 0.059 0.0 HOH
 2.452
 O
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 LEU A:32 A:33 34.0 0.2 -128.4 146.8 34.0 0.2 0.0 HOH
 2.411
 O
 O
LEU B:32 B:33 40.0 0.235 -122.2 140.1 40.0 0.235 0.0 HOH
 4.035
 CB
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 LEU A:33 A:33 51.0 0.3 -115.0 138.4 51.0 0.3 0.0 HOH
 3.684
 CB
 O
LEU B:33 B:33 45.0 0.265 -107.4 128.1 45.0 0.265 0.0 HOH
 7.260
 C
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 LEU A:32 A:33 50.0 0.294 -110.6 130.3 50.0 0.294 0.0 HOH
 3.066
 N
 O
LEU B:32 B:33 28.0 0.165 -112.5 133.4 28.0 0.165 0.0 HOH
 2.793
 O
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 LEU A:32 1:33 44.0 0.259 -97.7 139.1 44.0 0.259 0.0 HOH
 3.949
 C
 O
LEU B:32 2:33 13.0 0.076 -104.3 134.5 13.0 0.076 0.0 HOH
 3.124
 N
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 LEU A:33 A:33 15.0 0.088 -99.3 141.0 15.0 0.088 0.0 HOH
 3.120
 N
 O
LEU B:33 B:33 12.0 0.071 -103.1 137.6 12.0 0.071 0.0 HOH
 3.166
 N
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 LEU A:32 A:33 46.0 0.271 -103.1 144.2 46.0 0.271 0.0 HOH
 4.452
 O
 O
LEU B:32 B:33 8.0 0.047 -116.0 133.1 8.0 0.047 0.0 HOH
 3.603
 CD2
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 LEU A:32 A:33 44.0 0.259 -106.0 136.7 44.0 0.259 0.0 HOH
 3.587
 CD1
 O
LEU B:32 B:33 8.0 0.047 -111.0 135.7 8.0 0.047 0.0 HOH
 3.379
 N
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 LEU A:33 A:33 21.0 0.124 -97.8 132.2 21.0 0.124 0.0 HOH
 2.863
 O
 O
LEU B:33 B:33 26.0 0.153 -105.8 135.5 26.0 0.153 0.0 HOH
 2.861
 N
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 LEU A:32 1:33 23.0 0.135 -103.2 132.8 23.0 0.135 0.0 HOH
 3.594
 CD1
 O
LEU B:32 2:33 23.0 0.135 -107.2 132.5 23.0 0.135 0.0 HOH
 4.164
 O
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 LEU A:32 A:33 54.0 0.318 -107.7 147.7 54.0 0.318 0.0 HOH
 5.853
 N
 O
LEU B:32 B:33 54.0 0.318 -101.3 141.9 54.0 0.318 0.0 HOH
 5.421
 N
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 LEU A:32 A:33 53.0 0.312 -116.6 140.9 53.0 0.312 0.0 HOH
 7.134
 C
 O
LEU B:32 B:33 57.0 0.335 -126.9 144.6 57.0 0.335 0.0 HOH
 8.931
 CD2
 O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 LEU A:32 A:33 19.0 0.112 -90.6 143.2 19.0 0.112 0.0 HOH
 3.249
 O
 O
LEU B:32 B:33 51.0 0.3 -97.3 146.6 51.0 0.3 0.0 HOH
 3.165
 O
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 LEU A:32 A:33 48.0 0.282 -101.0 141.5 48.0 0.282 0.0 HOH
 3.175
 CB
 O
LEU B:32 B:33 10.0 0.059 -105.1 137.0 10.0 0.059 0.0 HOH
 2.708
 O
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 LEU A:32 A:33 51.0 0.3 -99.8 143.4 51.0 0.3 0.0 HOH
 6.102
 CD1
 O
LEU B:32 B:33 50.0 0.294 -106.3 140.9 50.0 0.294 0.0 SO4
GOL
HOH
 3.123
8.489
5.592
 CB
N
N
 O3
C1
O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 LEU A:32 A:33 92.0 0.541 -9.1 122.0 92.0 0.541 0.0
LEU B:32 B:33 51.0 0.3 -115.4 147.0 51.0 0.3 0.0
2iam 3 P60174 93.33 1.0 X-RAY
 2007-04-03 VAL C:12 P:34 125.0 0.806 -62.3 160.3 7.0 0.045 0.761 B:P04229:0.342
A:P01903:0.594
 HOH
 7.306
 CG2
 O
2ian 3 P60174 100.0 1.0 X-RAY
 2007-04-03 VAL C:12 C:34 127.0 0.819 -74.6 154.4 7.0 0.045 0.774 B:P04229:0.368
A:P01903:0.594
 HOH
 7.737
 O
 O
VAL H:12 H:34 122.0 0.787 -59.2 148.6 NA NA NA
VAL M:12 M:34 126.0 0.813 -71.9 153.5 NA NA NA
VAL R:12 R:34 128.0 0.826 -73.3 154.4 NA NA NA
4e41 3 P60174 93.33 1.0 X-RAY
 2012-08-29 VAL C:12 C:34 124.0 0.8 -70.5 154.8 7.0 0.045 0.755 B:P04229:0.361
A:P01903:0.555
 HOH
 5.841
 CG1
 O
VAL H:12 H:34 127.0 0.819 -70.6 153.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 VAL A:34 A:34 31.0 0.2 -92.3 124.5