Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr12 6978037 . G A CCDS53740.1:NM_001159287.1:c.236tGt>tAt_NP_001152759.1:p.79C>Y Homo sapiens triosephosphate isomerase 1 (TPI1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6up1 1 P60174 100.0 0.0 X-RAY
 2020-07-01 CYS A:45 A:41 0.0 0.0 E -117.8 135.1 0.0 0.0 0.0 HOH
 3.643
 SG
 O
CYS B:45 B:41 0.0 0.0 E -115.2 136.1 0.0 0.0 0.0 HOH
 3.759
 SG
 O
6up5 1 P60174 100.0 0.0 X-RAY
 2020-07-01 CYS A:45 A:41 0.0 0.0 E -118.1 133.7 0.0 0.0 0.0 HOH
 3.563
 SG
 O
CYS B:45 B:41 0.0 0.0 E -114.3 133.3 0.0 0.0 0.0 HOH
 3.770
 SG
 O
4poc 1 P60174 100.0 0.0 X-RAY
 2015-01-14 CYS A:47 A:41 0.0 0.0 E -119.6 136.9 0.0 0.0 0.0 HOH
 3.695
 SG
 O
CYS B:47 B:41 0.0 0.0 E -116.6 135.7 0.0 0.0 0.0 HOH
 3.882
 SG
 O
6c2g 1 P60174 99.6 0.0 X-RAY
 2018-03-21 CYS A:42 A:41 0.0 0.0 E -121.5 132.5 0.0 0.0 0.0 HOH
 3.457
 SG
 O
CYS B:42 B:41 0.0 0.0 E -122.2 132.0 NA NA NA
CYS C:42 C:41 0.0 0.0 E -121.4 132.4 NA NA NA
CYS D:42 D:41 0.0 0.0 E -121.7 132.4 NA NA NA
4pod 1 P60174 99.6 0.0 X-RAY
 2015-01-14 CYS A:47 A:41 0.0 0.0 E -117.7 134.1 0.0 0.0 0.0 HOH
 6.523
 H
 O
CYS B:47 B:41 0.0 0.0 E -112.3 132.9 0.0 0.0 0.0 HOH
 6.721
 H
 O
1wyi 1 P60174 100.0 0.0 X-RAY
 2005-04-12 CYS A:43 A:41 0.0 0.0 E -120.2 127.5 0.0 0.0 0.0 HOH
 3.513
 SG
 O
CYS B:43 B:41 0.0 0.0 E -114.6 123.0 0.0 0.0 0.0 HOH
 2.560
 O
 O
2jk2 1 P60174 100.0 0.0 X-RAY
 2008-07-01 CYS A:43 A:41 0.0 0.0 E -119.0 137.9 0.0 0.0 0.0 HOH
 3.700
 SG
 O
CYS B:43 B:41 0.0 0.0 E -116.7 133.8 0.0 0.0 0.0 HOH
 3.689
 SG
 O
6up8 1 P60174 99.6 0.0 X-RAY
 2020-07-01 CYS A:45 A:41 1.0 0.007 E -113.1 135.9 1.0 0.007 0.0 HOH
 7.074
 N
 O
CYS B:45 B:41 0.0 0.0 E -123.2 134.3 0.0 0.0 0.0 HOH
 7.115
 O
 O
6upf 1 P60174 99.6 0.0 X-RAY
 2020-07-01 CYS A:45 A:41 0.0 0.0 E -115.0 134.5 0.0 0.0 0.0 HOH
 7.098
 O
 O
CYS B:45 B:41 0.0 0.0 E -111.2 133.0 0.0 0.0 0.0 HOH
 7.074
 N
 O
1hti 1 P60174 100.0 0.0 X-RAY
 1995-01-26 CYS A:41 A:41 0.0 0.0 E -112.6 143.4 0.0 0.0 0.0
CYS B:41 B:41 0.0 0.0 E -130.7 120.9 0.0 0.0 0.0
4zvj 1 P60174 99.6 0.0 X-RAY
 2016-03-09 CYS A:47 A:41 0.0 0.0 E -118.4 134.5 0.0 0.0 0.0 HOH
 3.706
 SG
 O
CYS B:47 B:41 0.0 0.0 E -116.2 135.6 0.0 0.0 0.0 HOH
 3.747
 SG
 O
2vom 1 P60174 99.6 0.0 X-RAY
 2008-06-17 CYS A:43 A:41 0.0 0.0 E -116.9 136.0 0.0 0.0 0.0 HOH
 3.619
 SG
 O
CYS B:43 B:41 0.0 0.0 E -122.2 133.1 0.0 0.0 0.0 HOH
 6.980
 N
 O
CYS C:43 C:41 0.0 0.0 E -113.9 133.7 NA NA NA
CYS D:43 D:41 0.0 0.0 E -118.9 132.1 NA NA NA
4unk 1 P60174 99.6 0.0 X-RAY
 2015-02-04 CYS A:43 A:41 0.0 0.0 E -116.9 129.9 0.0 0.0 0.0 HOH
 7.130
 N
 O
CYS B:43 B:41 1.0 0.007 E -117.4 129.6 1.0 0.007 0.0 HOH
 7.195
 O
 O
4unl 1 P60174 99.6 0.0 X-RAY
 2015-02-04 CYS A:41 A:41 0.0 0.0 E -118.7 134.7 0.0 0.0 0.0 HOH
 3.717
 SG
 O
CYS B:41 B:41 0.0 0.0 E -116.3 136.2 0.0 0.0 0.0 HOH
 3.610
 SG
 O
4br1 1 P60174 100.0 0.0 X-RAY
 2013-06-12 CYS A:39 A:41 0.0 0.0 E -115.4 134.7 0.0 0.0 0.0 HOH
 3.614
 SG
 O
CYS B:39 B:41 0.0 0.0 E -116.7 133.4 0.0 0.0 0.0 HOH
 3.786
 SG
 O
6d43 1 P60174 100.0 0.0 X-RAY
 2018-05-16 CYS A:39 A:41 0.0 0.0 E -114.5 134.2 0.0 0.0 0.0 HOH
 3.457
 SG
 O
6d43 2 P60174 100.0 0.0 X-RAY
 2018-05-16 CYS B:39 B:41 0.0 0.0 E -114.3 133.2 0.0 0.0 0.0 HOH
 3.764
 SG
 O
1r2r 1 P00939 98.39 0.0 X-RAY
 2003-12-23 CYS A:41 A:41 0.0 0.0 E -118.9 135.9 0.0 0.0 0.0 HOH
 3.662
 SG
 O
CYS B:41 B:41 0.0 0.0 E -118.2 138.1 0.0 0.0 0.0 HOH
 3.739
 SG
 O
CYS C:41 C:41 0.0 0.0 E -117.0 134.9 NA NA NA
CYS D:41 D:41 0.0 0.0 E -116.1 137.7 NA NA NA
1r2s 1 P00939 98.39 0.0 X-RAY
 2003-12-23 CYS A:41 A:41 0.0 0.0 E -114.8 140.6 0.0 0.0 0.0 HOH
 7.796
 O
 O
CYS B:41 B:41 0.0 0.0 E -114.5 140.3 0.0 0.0 0.0 HOH
 7.564
 O
 O
CYS C:41 C:41 0.0 0.0 E -119.0 140.0 NA NA NA
CYS D:41 D:41 0.0 0.0 E -111.9 140.1 NA NA NA
1r2t 1 P00939 98.39 0.0 X-RAY
 2003-12-23 CYS A:41 A:41 0.0 0.0 E -117.7 132.9 0.0 0.0 0.0 HOH
 3.581
 SG
 O
CYS B:41 B:41 0.0 0.0 E -120.4 131.7 0.0 0.0 0.0 HOH
 3.751
 SG
 O
4owg 1 P00939 98.39 0.0 X-RAY
 2014-03-05 CYS A:41 A:41 0.0 0.0 E -124.1 136.2 0.0 0.0 0.0 HOH
 3.594
 SG
 O
CYS B:41 B:41 0.0 0.0 E -119.5 137.7 0.0 0.0 0.0 HOH
 3.737
 SG
 O
6nlh 1 P60174 99.59 0.0 X-RAY
 2019-06-19 CYS A:38 A:41 0.0 0.0 E -120.2 136.1 0.0 0.0 0.0 HOH
 3.567
 SG
 O
CYS B:38 E:41 0.0 0.0 E -122.5 131.5 0.0 0.0 0.0 HOH
 3.878
 SG
 O
CYS C:38 B:41 0.0 0.0 E -122.9 132.7 NA NA NA
CYS D:38 C:41 0.0 0.0 E -119.1 133.4 NA NA NA
CYS E:38 D:41 0.0 0.0 E -119.6 137.2 NA NA NA
CYS F:38 F:41 0.0 0.0 E -117.7 131.4 NA NA NA
CYS G:38 G:41 0.0 0.0 E -122.3 135.2 NA NA NA
CYS H:38 H:41 0.0 0.0 E -119.6 133.3 NA NA NA
1sw3 1 P00940 89.16 1e-162 X-RAY
 2004-08-24 CYS A:41 A:41 1.0 0.007 E -110.6 126.9 1.0 0.007 0.0 HOH
 6.962
 N
 O
CYS B:41 B:41 1.0 0.007 E -111.8 124.7 1.0 0.007 0.0 HOH
 7.211
 N
 O
1tph 1 P00940 89.39 7e-162 X-RAY
 1994-04-30 CYS A:40 1:41 1.0 0.007 E -111.1 127.4 1.0 0.007 0.0 HOH
 3.700
 SG
 O
CYS B:40 2:41 0.0 0.0 E -111.3 120.9 0.0 0.0 0.0 HOH
 3.891
 SG
 O
8tim 1 P00940 89.39 7e-162 X-RAY
 1999-02-16 CYS A:40 A:41 2.0 0.015 E -114.0 135.6 2.0 0.015 0.0 HOH
 6.990
 O
 O
CYS B:40 B:41 2.0 0.015 E -119.6 128.9 2.0 0.015 0.0 HOH
 9.991
 SG
 O
1sw7 1 P00940 88.35 8e-162 X-RAY
 2004-08-24 CYS A:41 A:41 0.0 0.0 E -109.5 118.6 0.0 0.0 0.0 HOH
 4.029
 SG
 O
CYS B:41 B:41 0.0 0.0 E -112.8 127.9 0.0 0.0 0.0 HOH
 3.853
 SG
 O
1spq 1 P00940 89.39 1e-161 X-RAY
 2004-08-24 CYS A:40 A:41 1.0 0.007 E -108.5 126.9 1.0 0.007 0.0 HOH
 3.819
 SG
 O
CYS B:40 B:41 1.0 0.007 E -110.2 126.4 1.0 0.007 0.0 HOH
 4.048
 SG
 O
1tpb 1 P00940 88.98 2e-161 X-RAY
 1995-02-14 CYS A:40 1:41 1.0 0.007 E -106.3 126.8 1.0 0.007 0.0 HOH
 7.219
 N
 O
CYS B:40 2:41 1.0 0.007 E -110.4 124.9 1.0 0.007 0.0 HOH
 7.277
 O
 O
1sw0 1 P00940 88.76 6e-161 X-RAY
 2004-08-24 CYS A:41 A:41 1.0 0.007 E -114.2 127.5 1.0 0.007 0.0 HOH
 4.015
 SG
 O
CYS B:41 B:41 1.0 0.007 E -114.0 121.4 1.0 0.007 0.0 HOH
 4.067
 SG
 O
1tpw 1 P00940 88.98 8e-161 X-RAY
 1995-04-20 CYS A:40 A:41 0.0 0.0 E -122.7 141.6 0.0 0.0 0.0 HOH
 7.270
 N
 O
CYS B:40 B:41 1.0 0.007 E -102.1 127.5 1.0 0.007 0.0 HOH
 6.802
 N
 O
1tpu 1 P00940 88.98 1e-160 X-RAY
 1995-04-20 CYS A:40 A:41 1.0 0.007 E -107.7 129.4 1.0 0.007 0.0 HOH
 3.793
 SG
 O
CYS B:40 B:41 1.0 0.007 E -108.6 134.4 1.0 0.007 0.0 HOH
 7.378
 O
 O
4p61 1 P00940 88.76 2e-160 X-RAY
 2014-08-27 CYS A:41 A:41 0.0 0.0 E -107.6 127.2 0.0 0.0 0.0 HOH
 3.797
 SG
 O
CYS B:41 B:41 0.0 0.0 E -108.6 125.7 0.0 0.0 0.0 HOH
 3.666
 SG
 O
1tpc 1 P00940 88.57 2e-160 X-RAY
 1995-02-14 CYS A:40 1:41 0.0 0.0 E -112.4 133.9 0.0 0.0 0.0 HOH
 3.828
 SG
 O
CYS B:40 2:41 1.0 0.007 E -106.9 122.6 1.0 0.007 0.0 HOH
 6.997
 N
 O
1ssd 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 CYS A:40 A:41 1.0 0.007 E -115.8 121.6 1.0 0.007 0.0 HOH
 7.635
 O
 O
CYS B:40 B:41 1.0 0.007 E -113.3 130.2 1.0 0.007 0.0 HOH
 7.342
 O
 O
1ssg 1 P00940 88.57 3e-160 X-RAY
 2004-08-24 CYS A:40 A:41 0.0 0.0 E -111.4 121.4 0.0 0.0 0.0 HOH
 4.353
 SG
 O
CYS B:40 B:41 1.0 0.007 E -115.6 125.0 1.0 0.007 0.0 HOH
 4.052
 SG
 O
1sq7 1 P00940 88.98 4e-160 X-RAY
 2004-08-24 CYS A:40 A:41 0.0 0.0 E -105.0 120.5 0.0 0.0 0.0 HOH
 7.664
 O
 O
CYS B:40 B:41 0.0 0.0 E -108.1 122.7 0.0 0.0 0.0 HOH
 6.879
 SG
 O
1tpv 1 P00940 88.57 1e-159 X-RAY
 1995-04-20 CYS A:40 A:41 1.0 0.007 E -111.9 131.6 1.0 0.007 0.0 HOH
 7.489
 O
 O
CYS B:40 B:41 1.0 0.007 E -108.1 134.1 1.0 0.007 0.0 HOH
 7.174
 N
 O
1su5 1 P00940 88.57 1e-159 X-RAY
 2004-08-24 CYS A:40 A:41 0.0 0.0 E -118.6 121.5 0.0 0.0 0.0 HOH
 3.763
 SG
 O
CYS B:40 B:41 0.0 0.0 E -121.8 120.1 0.0 0.0 0.0 SO4
HOH
 9.484
3.947
 SG
SG
 O3
O
1tim 1 P00940 86.53 5e-158 X-RAY
 1976-10-15 CYS A:40 A:41 1.0 0.007 E -99.0 135.3 1.0 0.007 0.0
CYS B:40 B:41 7.0 0.052 E -130.8 139.7 7.0 0.052 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60174-f1 1 P60174 100.0 0.0 CYS A:42 A:42 0.0 0.0 E -111.6 130.3